Triply periodic minimal surface (TPMS) porous structures: from multi-scale design, precise additive manufacturing to multidisciplinary applications

International Journal of Extreme Manufacturing, Год журнала: 2022, Номер 4(2), С. 022001 - 022001

Опубликована: Март 9, 2022

Abstract Inspired by natural porous architectures, numerous attempts have been made to generate structures. Owing the smooth surfaces, highly interconnected and mathematical controllable geometry features, triply periodic minimal surface (TPMS) is emerging as an outstanding solution constructing structures in recent years. However, many advantages of TPMS are not fully utilized current research. Critical problems process from design, manufacturing applications need further systematic integrated discussions. In this work, a comprehensive overview provided. order digital models TPMS, design algorithms performance control strategies introduced according diverse requirements. Based on that, precise additive methods summarized for fabricating physical products. Furthermore, actual multidisciplinary presented clarify potential Eventually, existing research outlooks discussed.

Язык: Английский

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Additively manufactured metallic biomaterials

Bioactive Materials, Год журнала: 2021, Номер 15, С. 214 - 249

Опубликована: Дек. 30, 2021

Metal additive manufacturing (AM) has led to an evolution in the design and fabrication of hard tissue substitutes, enabling personalized implants address each patient's specific needs. In addition, internal pore architectures integrated within additively manufactured scaffolds, have provided opportunity further develop engineer functional for better integration, long-term durability. this review, latest advances different aspects metallic biomaterials are highlighted. After introducing metal AM processes, biocompatible metals adapted integration with machines presented. Then, we elaborate on tools approaches undertaken porous scaffold engineered architecture including, topology optimization techniques, as well unit cell patterns based lattice networks, triply periodic minimal surface. Here, new possibilities brought by functionally gradient structures meet conflicting requirements thoroughly discussed. Subsequently, constraints physical characteristics constructs reviewed terms input parameters such features processing parameters. We assess proposed applications regeneration types efforts made towards their clinical translation. Finally, conclude review emerging directions perspectives development medical industry.

Язык: Английский

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Application of TPMS structure in bone regeneration

Engineered Regeneration, Год журнала: 2021, Номер 2, С. 154 - 162

Опубликована: Янв. 1, 2021

Bone defect repair, due to its complex process in nature, has become a costly issue modern day medicine. This causes growing demand for bone substitute that is effective and easy construct. Recently, triply periodic minimal surface (TPMS) scaffolds, which embody trabecular bone-mimicking hyperboloidal topography, have promising candidate this exact role their unique structure promote many cellular processes. In response the popularity of TPMS scaffolds amongst researchers, review discusses effect different parameters (including pore size, porosity, shape, as well influences on mechanical property, permeability, curvature), along with controlling designing such parameters, regeneration serve guide future researchers utilizing purposes.

Язык: Английский

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Isotropic porous structure design methods based on triply periodic minimal surfaces

Materials & Design, Год журнала: 2021, Номер 210, С. 110050 - 110050

Опубликована: Авг. 18, 2021

Recently, triply periodic minimal surface (TPMS) is emerging as an ideal tool to generate porous structures. Yet, most of the current work only focuses on controlling elastic modulus by relative density. For special engineering applications, such bone implants or energy absorbers, generated TPMS may still be broken due anisotropy. In this work, two strategies are proposed design isotropic The numerical homogenization theory and finite element analysis methods utilized study relationship between parameters anisotropy properties. Based that, a Curvature-Wall thickness (CW) adjustment method for sheet structures whose performances close isotropy virtue constructed map, both properties can controlled. far from properties, units combined composite TPMS, which further designed method. Experimental results verify effectiveness accuracy approaches. Appropriate acquired at same time.

Язык: Английский

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Recent progress in gradient-structured metals and alloys

Progress in Materials Science, Год журнала: 2023, Номер 140, С. 101194 - 101194

Опубликована: Сен. 29, 2023

Язык: Английский

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Design exploration of 3D-printed triply periodic minimal surface scaffolds for bone implants

International Journal of Mechanical Sciences, Год журнала: 2021, Номер 211, С. 106762 - 106762

Опубликована: Авг. 28, 2021

Язык: Английский

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Mechanical responses of sheet-based gyroid-type triply periodic minimal surface lattice structures fabricated using selective laser melting

Materials & Design, Год журнала: 2022, Номер 214, С. 110407 - 110407

Опубликована: Янв. 19, 2022

Owing to their lightweight design, high energy absorption capacity, and excellent thermal sound insulation properties, lattice structures have many potential applications in the fields of security, aerospace, biomedicine, heat dissipation. In this study, a gyroid-type triply periodic minimal surface is used design structures. Gyroid uniform gyroid graded are mathematically designed fabricated using selective laser melting with SS 316 L stainless steel powder. The mechanical properties these studied under compression load, deformation differences between compared. finite element method simulate process, experimental simulation results qualitatively Results show that during plastic deformation, stress change structure larger than structure. By controlling volume fraction, can be specifically tailored, which provides guidelines for application

Язык: Английский

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Design of a biomimetic graded TPMS scaffold with quantitatively adjustable pore size

Materials & Design, Год журнала: 2022, Номер 218, С. 110665 - 110665

Опубликована: Апрель 20, 2022

The advantages of "printing the right material in position" and unique structure for function" additive manufacturing make design biomimetic graded scaffold bone tissue engineering possible. Here, under different porosities, we propose a TPMS with adjustable pore size, providing guidance designing porous implants without characteristics stress concentration, shielding barrier mass transport. Specifically, structural can be achieved concentration. By adjusting porosity, elastic modulus Ti6Al4V samples adjusted range 1158–4567 MPa, which match individual selection mechanical properties biological bone. Since is designed by layer-by-layer splicing, through height parameters single-layer structure, selective size variation realized to further transport Then, vitro culture experiments have been conducted maximum cell survival rate an offset constant 0.4 85.44%, meet implants. As such, proposed this paper shows excellent potential orthopedic

Язык: Английский

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High‐Strength Hydroxyapatite Scaffolds with Minimal Surface Macrostructures for Load‐Bearing Bone Regeneration

Advanced Functional Materials, Год журнала: 2022, Номер 32(33)

Опубликована: Июнь 9, 2022

Abstract Triply periodic minimum surfaces (TPMS), which outperform other structures in terms of bulk moduli and relative density, have been widely used to dramatically improve the mechanical strength natural echinoderm skeletons engineered scaffolds. Herein, TPMS‐structure‐based 3D‐printed hydroxyapatite (HAp) scaffolds highly their limited evaluate underlying mechanism match biological bone repair process as a regeneration scaffold are constructed. The results show that HAp greater compressive range is sufficient meet requirements for human cortical trabecular bone, traditional with Cross‐hatch strength, cell osteogenic differentiation. reduction stress concentration open‐cell permeable structure Split‐P can benefit generation ingrowth new after vivo implantation rabbit femur bone. Furthermore, RNA‐seq immunochemistry staining samples unravel time sequence. optimized TPMS macrostructures an in‐depth understanding mechanisms will contribute development materials perform on par load‐bearing

Язык: Английский

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Recent advances in GelMA hydrogel transplantation for musculoskeletal disorders and related disease treatment

Theranostics, Год журнала: 2023, Номер 13(6), С. 2015 - 2039

Опубликована: Янв. 1, 2023

Increasing data reveals that gelatin has been methacrylated is involved in a variety of physiologic processes are important for therapeutic interventions. Gelatin methacryloyl (GelMA) hydrogel highly attractive hydrogels-based bioink because its good biocompatibility, low cost, and photo-cross-linking structure useful cell survivability monitoring. Methacrylated established itself as typical composition with extensive biomedical applications. Recent advances GelMA have focused on integrating them bioactive functional nanomaterials, the goal improving GelMA's physical, chemical, biological properties. ability to modify characteristics due synthesis technique also makes it choice soft hard tissues. become an independent or supplementary technology musculoskeletal problems. Here, we systematically review mechanism-of-action, uses, challenges future direction disorders. We give overview nanocomposite different applications disorders, such osteoarthritis, intervertebral disc degeneration, bone regeneration, tendon disorders so on.

Язык: Английский

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