Optics Express, Год журнала: 2024, Номер 32(17), С. 29265 - 29265
Опубликована: Июль 24, 2024
The longitudinal relaxation time (termed as T
Язык: Английский
Nano-Structures & Nano-Objects, Год журнала: 2024, Номер 37, С. 101103 - 101103
Опубликована: Фев. 1, 2024
Язык: Английский
Процитировано
28
Accounts of Chemical Research, Год журнала: 2022, Номер 55(24), С. 3572 - 3580
Опубликована: Дек. 7, 2022
Relaxometry is a technique which makes use of specific crystal lattice defect in diamond, the so-called NV center. This consists nitrogen atom, replaces carbon atom diamond lattice, and an adjacent vacancy. centers allow converting magnetic noise into optical signals, dramatically increases sensitivity readout, allowing for nanoscale resolution. Analogously to T1 measurements conventional resonance imaging (MRI), relaxometry allows detection different concentrations paramagnetic species. However, since very local measurements, detected signals are from voxels around centers. As result, it possible achieve subcellular resolutions organelle measurements.A experiment starts with polarizing spins using strong laser pulse. Afterward switched off allowed stochastically decay equilibrium mix states. The polarized configuration exhibits stronger fluorescence than state, one optically monitor this transition determine its rate. process happens faster at higher levels noise. Alternatively, conduct relaxation dark bright by applying microwave pulse brings -1 state instead 0 state. One can record spectrum varying strengths applied field. called cross-relaxometry. Apart detecting responsive coatings be render sensitive other parameters as pH, temperature, or electric Depending on application there three ways experiments: moving stationary nanodiamonds, scanning magnetometry, bulk sample top.In Account, we present examples various modes well their advantages limitations. Due simplicity low cost approach, has been implemented many instruments wide range applications. Herein review progress that achieved physics, chemistry, biology. Many articles field have proof-of-principle character, full potential technology still waits unfolded. With would like stimulate discourse future relaxometry.
Язык: Английский
Процитировано
56
Cancer Letters, Год журнала: 2024, Номер 587, С. 216710 - 216710
Опубликована: Фев. 16, 2024
Язык: Английский
Процитировано
9
Desalination, Год журнала: 2024, Номер 574, С. 117277 - 117277
Опубликована: Янв. 3, 2024
The review concludes with a broad spectrum of practical applications concerted PVDF-CNM membrane materials dedicated for liquid and gas separation, significant focus on the desalination process. research is carried out in diverse science fields, merging chemistry engineering toward frequently multimodal functionalities. Hence, there high demand comprehensive these cutting-edge-materials from across fundamental sciences technologies. main goals work are linking structure PVDF (phases) CNMs (carbon atom hybridization) physico-chemical properties PVDF-CNMs materials. Moreover, attention was paid simplicity generation having huge potential tuning various features obtained (e.g., hydrophilicity, mechanical properties, catalytic activity, bioactivity). Additionally, new directions exploration have been indicated.
Язык: Английский
Процитировано
8
PNAS Nexus, Год журнала: 2024, Номер 3(5)
Опубликована: Апрель 30, 2024
Abstract Nanodiamonds (NDs) comprise a family of carbon-based nanomaterials (i.e. diameter <100 nm) with the same sp3 lattice structure that gives natural diamonds their exceptional hardness and electrical insulating properties. Among all carbon nanomaterials—e.g. nanotubes, nanodots, fullerenes—NDs are particular interest for biomedical applications because they offer high biocompatibility, stability in vivo, dynamic surface chemistry can be manipulated to perform seemingly limitless variety ultra-specific tasks. NDs already deepening our understanding basic biological processes, while numerous laboratories continue studying these an aim making seismic improvements prevention, diagnosis, treatment human diseases. This review surveys approximately 2,000 most recent articles published last 5 years includes references more than 150 relevant publications on NDs. The findings categorized by contemporary lines investigation based potential applications, namely: genetics gene editing, drug delivery systems, neural interfacing, sensors, synthetic biology, organ tissue regeneration. also brief background methods currently developed synthesis preparation. Finally, recommendations future investigations offered.
Язык: Английский
Процитировано
8
Frontiers in Nutrition, Год журнала: 2024, Номер 11
Опубликована: Фев. 6, 2024
Amomum villosum Lour. ( A. ), known as Sharen in China, is widely used for culinary and medicinal purposes due to containing a diverse set of bioactive compounds. In this study, the optimum ethanol extraction process was optimized composition biological activities (antioxidant antitumor) five different fractions (dichloromethane, petroleum ether, ethyl acetate, n -butanol H 2 O) extracted from extract were investigated. The results showed that optimal conditions temperature 80°C, time 120 min, concentration 40% solid–liquid ratio 1:25 g/mL. Moreover, 35 compounds successfully identified by UPLC-ESI-QTOF-MS/MS factions first time, including 12 phenolic acids derivatives, organic acids, flavonoids oxylipins 7 proanthocyanidins. Among them, acetate fraction (Fr-EtOAc) exhibited highest content total (374.01 mg GAE/g DW) flavonoid (93.11 RE/g DW), where vanillic acid, catechin, epicatechin protocatechuic acid predominant accounting 81.65% quantified addition, Fr-EtOAc demonstrated excellent antioxidant activity (IC 50 DPPH ABTS assays 0.23, 0.08 mg/mL, respectively, FRAP assay 322.91 VCE/100 g antitumor (1,000 μg/mL, 79.04% inhibition rate). could provide guidance industrial production application villosum.
Язык: Английский
Процитировано
7
Nanophotonics, Год журнала: 2023, Номер 12(3), С. 485 - 494
Опубликована: Фев. 1, 2023
Diamond color centers have been widely studied in the field of quantum optics. The negatively charged silicon vacancy (SiV
Язык: Английский
Процитировано
11
Nanotechnology, Год журнала: 2023, Номер 34(19), С. 195702 - 195702
Опубликована: Фев. 6, 2023
A systematic spectroscopic characterization of highly homogeneous water suspensions 'buckydiamonds' comprising sp3cubic nanodiamond (ND) core covered with disordered sp2shell densely decorated oxygen-containing groups demonstrates the excitation-wavelength-dependent photoluminescence (PL) given by at least four types specific structures on ND surface (hydroxyl, C=O containing ketones, carboxylic anhydrides, and carboxyl groups). PL properties NDs possess concentration-dependent behavior revealing tendency to agglomerate. has been found be strongly sensitive pH environment in wide range values, i.e. 2-11. We disclosed mechanisms sensitivity 'buckydiamond' proved that it can serve as all-optical sensor tiny variations suitable for further exploitation sensing locally area where have delivered any purpose, e.g. bioimaging or therapeutic needs.
Язык: Английский
Процитировано
11
Ultrasonics Sonochemistry, Год журнала: 2023, Номер 99, С. 106563 - 106563
Опубликована: Авг. 20, 2023
In biomedical research, ultrasonic cavitation, especially inertial cavitation (IC) has attracted extensive attentions due to its ability induce mechanical, chemical and thermal effects. Like ultrasound contrast agent (UCA) microbubbles or droplets, acoustic can be effectively triggered beyond a certain pressure threshold through the interaction between nucleation particles, leading an enhanced thrombolytic effect. As newly developed nanocarbon material, nitrogen-doped annealed nanodiamond (N-AND) shown promising catalytic performance. To further explore effects on N-AND was synthesized at temperature of 1000 °C. After systematic material characterization, potential IC activity assessed for first time by using passive detection (PCD). Based experiments performed varied suspension concentration cycle number, demonstrated strong capability generate significant characteristics, indicating formation stable bubbles from surface materials. Furthermore, applied in vitro thrombolysis verify contribution thrombolysis. The influence hydrophobicity potentials ND innovatively discussed combination with theory mote-induced nucleation. It is found that stability better than commercial UCA microbubbles. This study would provide understanding novel carbonous nanomaterials as nuclei expected guidance their future industrial applications.
Язык: Английский
Процитировано
10
Nanomaterials, Год журнала: 2024, Номер 14(15), С. 1318 - 1318
Опубликована: Авг. 5, 2024
Optically active color centers in diamond and nanodiamonds can be utilized as quantum sensors for measuring various physical parameters, particularly magnetic electric fields, well temperature. Due to their small size possible surface functionalization, fluorescent are extremely attractive systems biological medical applications since they used intracellular experiments. This review focuses on thermometry with high sensitivity a nanoscale spatial resolution the investigation of living systems. The current state art, further development, potential limitations thermometers will discussed here.
Язык: Английский
Процитировано
4