Biofabrication,
Год журнала:
2024,
Номер
16(4), С. 042005 - 042005
Опубликована: Авг. 9, 2024
The
global
demand
for
an
enhanced
quality
of
life
and
extended
lifespan
has
driven
significant
advancements
in
tissue
engineering
regenerative
medicine.
These
fields
utilize
a
range
interdisciplinary
theories
techniques
to
repair
structurally
impaired
or
damaged
tissues
organs,
as
well
restore
their
normal
functions.
Nevertheless,
the
clinical
efficacy
medications,
materials,
potent
cells
used
at
laboratory
level
is
always
constrained
by
technological
limitations.
A
novel
platform
known
adaptable
microneedles
been
developed
address
abovementioned
issues.
offer
solution
localized
distribution
various
cargos
while
minimizing
invasiveness.
Microneedles
provide
favorable
patient
compliance
settings
due
effective
administration
ability
painless
convenient
process.
In
this
review
article,
we
summarized
most
recent
development
microneedles,
started
classifying
microneedle
systems,
advantages,
fundamental
properties.
Subsequently,
it
provides
comprehensive
overview
different
types
material
fabricate
properties
ideal
applications
medicine,
primarily
focusing
on
preserving
restoring
organs.
limitations
perspectives
have
discussed
concluding
future
therapeutic
medicines.
Bioactive Materials,
Год журнала:
2023,
Номер
33, С. 355 - 376
Опубликована: Ноя. 26, 2023
Natural
polymers
are
complex
organic
molecules
that
occur
in
the
natural
environment
and
have
not
been
subjected
to
artificial
synthesis.
They
frequently
encountered
various
creatures,
including
mammals,
plants,
microbes.
The
aforementioned
commonly
derived
from
renewable
sources,
possess
a
notable
level
of
compatibility
with
living
organisms,
limited
adverse
effect
on
environment.
As
result,
they
hold
considerable
significance
development
sustainable
environmentally
friendly
goods.
In
recent
times,
there
has
advancement
investigation
potential
uses
field
biomedicine,
specifically
relation
biomaterials
exhibit
antibacterial
antioxidant
characteristics.
This
review
provides
comprehensive
overview
prevalent
utilized
biomedical
domain
throughout
preceding
two
decades.
this
paper,
we
present
examination
components
typical
methods
for
preparation
based
polymers.
Furthermore,
summarize
application
polymer
materials
each
stage
skin
wound
repair.
Finally,
key
findings
insights
into
limitations
current
elucidate
prospects
their
future
field.
Advanced Materials,
Год журнала:
2023,
Номер
unknown
Опубликована: Авг. 11, 2023
Bioprinting
has
attracted
much
attention
due
to
its
suitability
for
fabricating
biomedical
devices.
In
particular,
bioprinting
become
one
of
the
growing
centers
in
field
wound
healing,
with
various
types
bioprinted
devices
being
developed,
including
3D
scaffolds,
microneedle
patches,
and
flexible
electronics.
Bioprinted
can
be
designed
specific
biostructures
biofunctions
that
closely
match
shape
sites
accelerate
regeneration
skin
through
approaches.
Herein,
a
comprehensive
review
smart
dressings
is
presented,
emphasizing
crucial
effect
determining
biofunctions.
The
begins
an
overview
techniques
devices,
followed
in-depth
discussion
polymer-based
inks,
modification
strategies,
additive
ingredients,
properties,
applications.
strategies
are
divided
into
seven
categories,
chemical
synthesis
novel
physical
blending,
coaxial
bioprinting,
multimaterial
absorption,
immobilization,
hybridization
living
cells,
examples
presented.
Thereafter,
frontiers
4D
artificial
intelligence-assisted
situ
discussed
from
perspective
interdisciplinary
sciences.
Finally,
current
challenges
future
prospects
this
highlighted.
Materials Horizons,
Год журнала:
2023,
Номер
10(9), С. 3237 - 3256
Опубликована: Янв. 1, 2023
This
work
highlights
the
animal
tissue-derived
biomaterials
in
wound
treatment
field
based
on
an
evaluation
of
their
critical
properties,
advanced
design
strategies
and
latest
applications.
Biomaterials Science,
Год журнала:
2023,
Номер
11(13), С. 4430 - 4451
Опубликована: Янв. 1, 2023
Wound
management
is
a
serious
concern
worldwide,
inflicting
huge
social
and
economic
burden
on
patients
healthcare
systems,
research
into
efficient
wound-management
measures
crucial.
npj Flexible Electronics,
Год журнала:
2024,
Номер
8(1)
Опубликована: Май 11, 2024
Abstract
Wound
infection
is
a
worldwide
health
issue
that
not
only
brings
large
detrimental
effects
to
people’s
physical
and
mental
health,
but
also
causes
substantial
economic
burdens
society.
By
using
traditional
surgical
debridement
antibiotic
therapy,
patients
generally
suffer
more
pain
are
at
risk
of
recurring
infections.
Thus,
the
development
non-antibiotic
treatment
methods
desperately
needed.
Currently,
emerging
flexible
wound
dressings
with
physiological
signal
detection,
inactivated
infectious
pathogen,
wound-healing
promoting
properties
has
exhibited
immense
potential
for
infected
wound.
Among
various
dressings,
MXene‐based
electronic
materials
as
special
electroactive,
mechanical,
photophysical,
biological
performances
possess
broad
application
prospect
in
healthcare.
In
this
review,
challenges
management
introduced.
Next,
types
MXene-based
features
outlined.
Then
recent
advance
detection
summarized.
Lastly,
predicaments,
prospects,
future
directions
discussed.
Abstract
Skin
wounds
have
become
an
important
issue
that
affects
human
health
and
burdens
global
medical
care.
Hydrogel
materials
similar
to
the
natural
extracellular
matrix
(ECM)
are
one
of
best
candidates
for
ideal
wound
dressings
most
feasible
choices
printing
inks.
Distinct
from
hydrogels
made
by
traditional
technologies,
which
lack
bionic
mechanical
properties,
3D
can
promptly
accurately
create
with
complex
bioactive
structures
potential
promote
tissue
regeneration
healing.
Herein,
a
comprehensive
review
multi‐functional
printing‐based
hydrogel
healing
is
presented.
The
first
summarizes
techniques
dressings,
including
photo‐curing,
extrusion,
inkjet,
laser‐assisted
printing.
Then,
properties
design
approaches
series
bioinks
composed
natural,
synthetic,
composite
polymers
described.
Thereafter,
application
in
variety
environments
discussed
depth,
hemostasis,
anti‐inflammation,
antibacterial,
skin
appendage
regeneration,
intelligent
monitoring,
machine
learning‐assisted
therapy.
Finally,
challenges
prospects
Deleted Journal,
Год журнала:
2024,
Номер
3(2), С. 200137 - 200137
Опубликована: Апрель 21, 2024
The
ability
of
organisms
to
adjust
environmental
changes
offers
valuable
insights
into
the
development
and
creation
innovative
smart
systems.
As
requirements
increase,
materials
change
their
shapes
has
become
a
broader
aim
beyond
original
capabilities.
In
contrast
conventional
manufacturing
methods,
additive
(AM)
skillfully
combines
precise
three-dimensional
structures
intricate
response
mechanisms
biological
with
materials.
This
combination
enables
production
bionic
programmable
features.
Trends
such
as
dynamic
modulation,
responsiveness
multiple
stimuli,
integration
functions
are
emerging
significant
in
structures.
review
first
presents
that
nature
designed
built
various
organisms,
highlighting
relationship
between
structural
characteristics
patterns
deformation.
then
discusses
how
developed
using
AM
techniques
respond
different
stimuli.
Additionally,
potential
uses
biomedicine,
intelligent
robotics,
origami
construction,
aerospace
discussed.
Finally,
challenges
future
prospects
for
examined
goal
offering
solutions
creating
next
generation
systems
through
interdisciplinary
research.
Journal of Biomaterials Science Polymer Edition,
Год журнала:
2024,
Номер
35(15), С. 2402 - 2445
Опубликована: Июль 17, 2024
Protein-based
wound
dressings
have
garnered
increasing
interest
in
recent
years
owing
to
their
distinct
physical,
chemical,
and
biological
characteristics.
The
intricate
molecular
composition
of
proteins
gives
rise
unique
characteristics,
such
as
exceptional
biocompatibility,
biodegradability,
responsiveness,
which
contribute
the
promotion
healing.
Wound
healing
is
an
ongoing
process
influenced
by
multiple
causes,
it
consists
four
phases.
Various
treatments
been
developed
repair
different
types
skin
wounds,
thanks
advancements
medical
technology
recognition
diverse
nature
wounds.
This
review
has
literature
reviewed
within
last
3-5
years-the
progress
development
protein
fundamental
properties
ideal
dressing.
Herein,
strides
protein-based
state-of-the-art
dressing
emphasize
significant
challenges
summarize
future
perspectives
for
applications.
