Journal of Nanobiotechnology,
Год журнала:
2024,
Номер
22(1)
Опубликована: Окт. 6, 2024
Inspired
by
the
concept
of
"natural
camouflage,"
biomimetic
drug
delivery
systems
have
emerged
to
address
limitations
traditional
synthetic
nanocarriers,
such
as
poor
targeting,
susceptibility
identification
and
clearance,
inadequate
biocompatibility,
low
permeability,
systemic
toxicity.
Biomimetic
nanocarriers
retain
proteins,
nucleic
acids,
other
components
parent
cells.
They
not
only
facilitate
but
also
serve
communication
media
inhibit
tumor
This
paper
delves
into
mechanisms
between
various
cell-derived
cells,
microenvironment,
well
their
applications
in
delivery.
In
addition,
additional
capabilities
conferred
on
modified
targeting
environmental
responsiveness,
are
outlined.
Finally,
we
propose
future
development
directions
for
hoping
inspire
researchers
design
efforts
ultimately
achieve
clinical
translation.
Journal of Nanobiotechnology,
Год журнала:
2024,
Номер
22(1)
Опубликована: Июнь 5, 2024
Chronic
hepatitis
B
poses
a
significant
global
burden,
modulating
immune
cells,
leading
to
chronic
inflammation
and
long-term
damage.
Due
its
hepatotropism,
the
virus
(HBV)
cannot
infect
other
cells.
The
mechanisms
underlying
intercellular
communication
among
different
liver
cells
in
HBV-infected
individuals
microenvironment
imbalance
remain
elusive.
Exosomes,
as
important
cargo
transportation
tools
between
hepatocytes
have
been
shown
assist
HBV
regulate
microenvironment.
However,
role
of
exosomes
has
only
gradually
received
attention
recent
years.
Minimal
literature
systematically
elaborated
on
reshaping
liver.
This
review
unfolds
sequentially
based
biological
processes
exosomes:
exosomes'
biogenesis,
release,
transport,
uptake
by
recipient
their
impact
We
delineate
how
influences
biogenesis
exosomes,
utilizing
exosomal
covert
transmission,
reshapes
hepatic
And
characteristics
functions
potential
applications
are
summarized
predicted.
Advanced Functional Materials,
Год журнала:
2024,
Номер
34(45)
Опубликована: Июль 11, 2024
Abstract
The
field
of
drug
delivery
has
significantly
advanced
tumor
therapy,
yet
challenges
such
as
the
predictability
treatment
outcomes
and
real‐time
monitoring
progression,
recurrence
or
metastasis.
Luminescent
metal–organic
frameworks
(L‐MOFs)
are
a
promising
solution
to
overcome
these
issues.
This
review
offers
comprehensive
exploration
design
synthesis
L‐MOFs,
presenting
their
crucial
optical
properties.
highlights
pivotal
role
L‐MOFs
in
enabling
precision
medicine
for
driven
by
performance.
Through
strategically
harnessing
light‐manipulated
(MOFs),
therapeutic
precise
spatiotemporal
control
can
be
achieved.
Moreover,
this
meticulously
examines
influence
photomanipulating
MOFs
on
situ
synthesis,
introducing
catalytic
gas
therapy.
Additionally,
gene
therapy
vectors
that
utilize
light
trigger
expression
responses
is
also
comprehensively
explored
article,
aiming
highlight
through
concludes
proposing
an
artificial
intelligence
(AI)‐mediated
blueprint
with
pave
way
innovative
approaches
manipulation.
Journal of Nanobiotechnology,
Год журнала:
2024,
Номер
22(1)
Опубликована: Окт. 6, 2024
Inspired
by
the
concept
of
"natural
camouflage,"
biomimetic
drug
delivery
systems
have
emerged
to
address
limitations
traditional
synthetic
nanocarriers,
such
as
poor
targeting,
susceptibility
identification
and
clearance,
inadequate
biocompatibility,
low
permeability,
systemic
toxicity.
Biomimetic
nanocarriers
retain
proteins,
nucleic
acids,
other
components
parent
cells.
They
not
only
facilitate
but
also
serve
communication
media
inhibit
tumor
This
paper
delves
into
mechanisms
between
various
cell-derived
cells,
microenvironment,
well
their
applications
in
delivery.
In
addition,
additional
capabilities
conferred
on
modified
targeting
environmental
responsiveness,
are
outlined.
Finally,
we
propose
future
development
directions
for
hoping
inspire
researchers
design
efforts
ultimately
achieve
clinical
translation.
