World Journal of Gastrointestinal Oncology,
Journal Year:
2025,
Volume and Issue:
17(4)
Published: March 24, 2025
Recently,
numerous
studies
have
reported
the
application
of
nanomedicines
in
colorectal
cancer
treatment.
However,
no
systematic
bibliometric
analysis
has
been
conducted
to
examine
potential
and
mechanisms
action
nanomedicine
this
context.
Such
an
may
provide
a
comprehensive
overview
current
research
landscape,
identify
emerging
trends,
highlight
key
areas
for
future
investigation.
To
describe
global
landscape
on
The
Web
Science
Core
Collection
database
was
searched
literature
published
from
January
1,
2010,
August
7,
2024,
focusing
Bibliometric
visualization
mapping
countries,
institutions,
authors,
keywords,
references
relevant
were
using
CiteSpace
(6.2R6),
VOSviewer
(1.6.20),
bibliometrix
(based
R
4.3.2).
A
total
3598
articles
included,
with
rapid
increase
publication
volume
starting
2010.
China
most
papers
topic,
followed
by
United
States
India.
emerged
as
central
country
field,
Egyptian
Knowledge
Bank
Chinese
Academy
Sciences
institutions
highest
number
publications.
exhibited
centrality.
prolific
author
Zhang
Y,
whereas
Siegel
RL
cited
author,
Li
Y
had
H-index.
International
Journal
Nanomedicine
publications
Biomaterials
received
citations.
Keyword
co-occurrence
identified
11837
keywords
grouped
into
13
clusters
15
high-frequency
highlighted
keywords.
top
three
keyword
"0
cancer",
"1
drug
delivery",
"2
being
"nanoparticles",
"colorectal
"drug
delivery".
Research
surged
since
"nanoparticles"
Future
should
investigate
nanomaterial
stability
target-specific
release.
Biotechnology Journal,
Journal Year:
2024,
Volume and Issue:
19(2)
Published: Feb. 1, 2024
Abstract
Exosomes
have
been
the
hidden
treasure
of
cell
in
terms
cellular
interactions,
transportation
and
therapy.
The
native
exosomes
(NEx)
secreted
by
parent
cells
hold
promising
aspects
cancer
diagnosis
NEx
has
low
immunogenicity,
high
biocompatibility,
toxicity
stability
which
enables
them
to
be
an
ideal
prognostic
biomarker
diagnosis.
However,
due
heterogeneity,
lacks
specificity
accuracy
used
as
therapeutic
drug
delivery
vehicle
Transforming
these
with
their
innate
structure
multiple
receptors
engineered
(EEx)
can
provide
better
opportunities
field
theranostics.
surface
exhibits
numeric
modified
pave
direction
its
Through
membrane,
EEx
increased
loading
potentiality
higher
target
act
a
nanocarrier
for
delivery.
This
review
provides
insights
into
tool
along
need
transformation
We
also
highlighted
different
methods
associated
transformations,
nano‐bio
interaction
recipient
major
challenges
clinical
application
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: June 5, 2024
Chronic
hepatitis
B
poses
a
significant
global
burden,
modulating
immune
cells,
leading
to
chronic
inflammation
and
long-term
damage.
Due
its
hepatotropism,
the
virus
(HBV)
cannot
infect
other
cells.
The
mechanisms
underlying
intercellular
communication
among
different
liver
cells
in
HBV-infected
individuals
microenvironment
imbalance
remain
elusive.
Exosomes,
as
important
cargo
transportation
tools
between
hepatocytes
have
been
shown
assist
HBV
regulate
microenvironment.
However,
role
of
exosomes
has
only
gradually
received
attention
recent
years.
Minimal
literature
systematically
elaborated
on
reshaping
liver.
This
review
unfolds
sequentially
based
biological
processes
exosomes:
exosomes'
biogenesis,
release,
transport,
uptake
by
recipient
their
impact
We
delineate
how
influences
biogenesis
exosomes,
utilizing
exosomal
covert
transmission,
reshapes
hepatic
And
characteristics
functions
potential
applications
are
summarized
predicted.
World Journal of Gastrointestinal Oncology,
Journal Year:
2025,
Volume and Issue:
17(4)
Published: March 24, 2025
Recently,
numerous
studies
have
reported
the
application
of
nanomedicines
in
colorectal
cancer
treatment.
However,
no
systematic
bibliometric
analysis
has
been
conducted
to
examine
potential
and
mechanisms
action
nanomedicine
this
context.
Such
an
may
provide
a
comprehensive
overview
current
research
landscape,
identify
emerging
trends,
highlight
key
areas
for
future
investigation.
To
describe
global
landscape
on
The
Web
Science
Core
Collection
database
was
searched
literature
published
from
January
1,
2010,
August
7,
2024,
focusing
Bibliometric
visualization
mapping
countries,
institutions,
authors,
keywords,
references
relevant
were
using
CiteSpace
(6.2R6),
VOSviewer
(1.6.20),
bibliometrix
(based
R
4.3.2).
A
total
3598
articles
included,
with
rapid
increase
publication
volume
starting
2010.
China
most
papers
topic,
followed
by
United
States
India.
emerged
as
central
country
field,
Egyptian
Knowledge
Bank
Chinese
Academy
Sciences
institutions
highest
number
publications.
exhibited
centrality.
prolific
author
Zhang
Y,
whereas
Siegel
RL
cited
author,
Li
Y
had
H-index.
International
Journal
Nanomedicine
publications
Biomaterials
received
citations.
Keyword
co-occurrence
identified
11837
keywords
grouped
into
13
clusters
15
high-frequency
highlighted
keywords.
top
three
keyword
"0
cancer",
"1
drug
delivery",
"2
being
"nanoparticles",
"colorectal
"drug
delivery".
Research
surged
since
"nanoparticles"
Future
should
investigate
nanomaterial
stability
target-specific
release.
