Journal of Materials Chemistry B, Год журнала: 2021, Номер 9(7), С. 1762 - 1780
Опубликована: Янв. 1, 2021
This review outlines progress in hydrogels with well-defined heterogeneity structures and responsiveness by using sequential synthesis, photolithography, 3D/4D printing, macroscopic assembling for programmable shape morphing or actuations.
Язык: Английский
Chemical Reviews, Год журнала: 2022, Номер 122(5), С. 5317 - 5364
Опубликована: Фев. 1, 2022
In conventional classification, soft robots feature mechanical compliance as the main distinguishing factor from traditional made of rigid materials. Recent advances in functional materials have facilitated emergence a new class capable tether-free actuation response to external stimuli such heat, light, solvent, or electric magnetic field. Among various types stimuli-responsive materials, shown remarkable progress their design and fabrication, leading development with unique advantages potential for many important applications. However, field is still its infancy requires further advancements terms principles, fabrication methods, control mechanisms, sensing modalities. Successful future would require comprehensive understanding fundamental principle actuation, well physical properties behavior this review, we discuss recent modeling simulation, robots. We then give set guidelines optimal performance Lastly, summarize biomedical applications provide our perspectives on next-generation
Язык: Английский
Процитировано
504
Materials Science and Engineering R Reports, Год журнала: 2021, Номер 145, С. 100596 - 100596
Опубликована: Апрель 2, 2021
Additive manufacturing (AM), also known as three-dimensional (3D) printing, has boomed over the last 30 years, and its use accelerated during 5 years. AM is a materials-oriented technology, printing resolution versus scalability/speed trade-off exists among various types of materials, including polymers, metals, ceramics, glasses, composite materials. Four-dimensional (4D) together with versatile transformation systems, drives researchers to achieve utilize high dimensional AM. Multiple perspectives structural materials have been raised illustrated in this review, multi-material (MMa-AM), multi-modulus (MMo-AM), multi-scale (MSc-AM), multi-system (MSy-AM), multi-dimensional (MD-AM), multi-function (MF-AM). The rapid tremendous development methods offers great potential for applications, such aerospace field, biomedical electronic devices, nuclear industry, flexible wearable soft sensors, actuators, robotics, jewelry art decorations, land transportation, underwater porous structures.
Язык: Английский
Процитировано
503
Molecular Pharmaceutics, Год журнала: 2019, Номер unknown
Опубликована: Дек. 26, 2019
As an emerging drug carrier, hydrogels have been widely used for tumor delivery. A hydrogel carrier can cause less severe side effects than systemic chemotherapy and achieve sustained delivery of a at sites. In addition, excellent biocompatibility biodegradability lower toxicity nanoparticle carriers. Smart respond to stimuli in the environment (e.g., heat, pH, light, ultrasound), enabling situ gelation controlled release, which greatly enhance convenience efficiency Here, we summarize different sizes cancer treatment their related routes, discuss design strategies stimuli-responsive hydrogels, review research concerning smart reported past few years.
Язык: Английский
Процитировано
363
Multifunctional Materials, Год журнала: 2020, Номер 3(4), С. 042003 - 042003
Опубликована: Ноя. 17, 2020
Abstract Magnetically responsive soft materials are composites where magnetic fillers embedded into polymeric matrices. These active have attracted extensive research and industrial interest due to their ability realize fast programmable shape changes through remote untethered control under the application of fields. They would many high-impact potential applications in robotics/devices, metamaterials, biomedical devices. With a broad range functional fillers, matrices, advanced fabrication techniques, material properties can be programmed for integrated functions, including morphing, dynamic deformation-based locomotion, object manipulation assembly, heat generation, as well reconfigurable electronics. In this review, an overview state-of-the-art developments future perspectives multifunctional magnetically is presented.
Язык: Английский
Процитировано
233
Advanced Science, Год журнала: 2023, Номер 10(28)
Опубликована: Авг. 6, 2023
Hydrogels with tailor-made swelling-shrinkable properties have aroused considerable interest in numerous biomedical domains. For example, as swelling is a key issue for blood and wound extrudates absorption, the transference of nutrients metabolites, well drug diffusion release, hydrogels high capacity been widely applicated full-thickness skin healing tissue regeneration, delivery. Nevertheless, fields adhesives internal soft-tissue healing, bioelectronics, non-swelling play very important functions owing to their stable macroscopic dimension physical performance physiological environment. Moreover, negative behavior (i.e., shrinkage) can be exploited drive noninvasive closure, achieve resolution enhancement hydrogel scaffolds. In addition, it help push out entrapped drugs, thus promote release. However, there still has not general review constructions applications from viewpoint properties. Therefore, this summarizes tactics employed so far tailoring applications. And relatively comprehensive understanding current progress future challenge different features provided potential clinical translations.
Язык: Английский
Процитировано
184
Advanced Functional Materials, Год журнала: 2020, Номер 30(50)
Опубликована: Сен. 15, 2020
Abstract Small‐scale magnetic soft‐bodied robots based on biocompatible and biodegradable materials are essential for their potential high‐impact minimally invasive medical applications inside the human body. Therefore, a strategy fully untethered soft millirobots with encoded 3D anisotropy static or dynamic shape programming is presented. Such robot body comprised of porcine extracellular matrix‐derived collagen‐based hydrogel network embedded superparamagnetic iron oxide nanoparticles (SPIONs). magnetization achieved by directionally self‐assembled SPION chains using an external permanent magnet. As proof‐of‐concept demonstration, milli‐gripper that can undergo flexible reversible deformations glycerol biologically relevant liquid media The gripper perform cargo grabbing, transportation rolling, release controlling field inputs. These milli‐grippers be completely degraded matrix metalloproteinase‐2 enzyme in physiologically concentrations. Furthermore, biocompatibility tests umbilical cord vein endothelial cells degradation products grippers demonstrate no acute toxicity. approach offers facile fabrication designing nanocomposite programmable toward future applications.
Язык: Английский
Процитировано
170
Applied Materials Today, Год журнала: 2021, Номер 26, С. 101306 - 101306
Опубликована: Дек. 20, 2021
Язык: Английский
Процитировано
164
Advanced Functional Materials, Год журнала: 2021, Номер 31(34)
Опубликована: Июнь 17, 2021
Abstract The research of functional magnetic materials has become a hot topic in the past few years due to their fast, long‐range, and precise response diverse environments. Functional devices using different structure designs have been developed demonstrated good advantages enable various applications. However, required for functions also increase fabrication difficulties while developing such devices. 3D printing technology presents powerful promising manufacturing approach rapidly fabricate complex geometries multiple scales. Here, strategies underlying mechanisms several primary applications are systematically reviewed, including, anisotropy property enhancement, robots, components electronics, magneto‐thermal Finally, current challenges future perspectives engineering printed discussed.
Язык: Английский
Процитировано
158
Journal of Controlled Release, Год журнала: 2021, Номер 335, С. 541 - 556
Опубликована: Июнь 11, 2021
Язык: Английский
Процитировано
150
Applied Surface Science Advances, Год журнала: 2023, Номер 18, С. 100462 - 100462
Опубликована: Окт. 1, 2023
The use of additive manufacturing, or 3D printing, has progressed beyond prototyping to produce intricate and valuable finished goods. potential manufacturing increased across numerous industries due the expansion materials, such as high-performance metals polymers, advancements in machine capabilities, multi-material printing. By enabling complex designs, reduced waste, quick production, it revolutionize consumer goods, healthcare, automotive aerospace industries. development specialized scaffolds been made possible by precise control that provides over internal structure porous materials. This technology revolutionized tissue engineering regenerative medicine. Furthermore, create individualized implants prosthetics improve patient comfort outcomes orthopedic dental applications. Also, flexibility design customization for Design flexibility, waste reduction, improved biocompatibility, prototyping, cost-effectiveness are benefits implants. For personalized medicine, better outcomes, holds promise develops with further printing speed, resolution, scalability.
Язык: Английский
Процитировано
149