Organic Letters,
Год журнала:
2022,
Номер
24(31), С. 5646 - 5650
Опубликована: Авг. 2, 2022
The
sturdy
chelation
of
1,2-diamines
and
transition-metals
would
retard
or
even
interrupt
the
routine
catalytic
cycles.
In
amidation
asymmetric
reductive
amination
(ARA)
cascade
reactions
diamines
ketoesters,
we
deployed
sets
additives
to
ensure
a
smooth
transformation
catalyzed
by
complexes
rhodium
versatile
highly
modular
phosphoramidite-phosphine
ligands.
tunability
ligands
was
fully
exploited
accommodate
various
α-ketoesters
for
efficient
synthesis
chiral
3,4-dihydroquinoxalinones.
European Journal of Organic Chemistry,
Год журнала:
2023,
Номер
26(37)
Опубликована: Июль 5, 2023
Abstract
This
review
summarizes
the
recent
progress
of
organocatalytic
and
biocatalytic
asymmetric
reductive
amination
(ARA),
a
challenging
but
important
topic
for
drug
discovery
pharmaceutical
industry.
At
present,
ARA
can
be
divided
into
three
categories:
metal
catalysis,
organic
biocatalysis.
In
past
decade,
transition
metal‐catalysed
has
been
well
established.
Organocatalytic
emerged
as
powerful
alternative
to
ARA,
hydrogen
sources
used
in
are
usually
Hantzsch
esters,
benzothiazolines,
boranes,
hydrosilanes,
which
require
Lewis
base
or
phosphoric
acid
catalysts
activate
them
give
secondary
chiral
amines.
It
is
worth
mentioning
that
made
remarkable
last
amino
dehydrogenases,
amine
opine
dehydrogenases
imine
reductases
have
successfully
ARA.
Catalysis Science & Technology,
Год журнала:
2023,
Номер
14(1), С. 98 - 109
Опубликована: Ноя. 22, 2023
Here
we
designed
and
synthesized
a
NN–Co
II
bidentate
complex
efficiently
used
it
for
general
expedient
amination
of
alcohols
under
benign,
solventless
conditions.
Green Chemistry,
Год журнала:
2022,
Номер
24(11), С. 4420 - 4424
Опубликована: Янв. 1, 2022
Rhodium-catalyzed
hydroaminomethylation
of
various
vinyl
arenes
with
anilines
has
been
accomplished
using
water
as
an
environmentally
benign
reaction
media.
Organic Letters,
Год журнала:
2022,
Номер
24(31), С. 5646 - 5650
Опубликована: Авг. 2, 2022
The
sturdy
chelation
of
1,2-diamines
and
transition-metals
would
retard
or
even
interrupt
the
routine
catalytic
cycles.
In
amidation
asymmetric
reductive
amination
(ARA)
cascade
reactions
diamines
ketoesters,
we
deployed
sets
additives
to
ensure
a
smooth
transformation
catalyzed
by
complexes
rhodium
versatile
highly
modular
phosphoramidite-phosphine
ligands.
tunability
ligands
was
fully
exploited
accommodate
various
α-ketoesters
for
efficient
synthesis
chiral
3,4-dihydroquinoxalinones.
