The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(4), С. 2322 - 2333
Опубликована: Янв. 26, 2023
An
efficient
and
practical
SO2
insertion
protocol
of
NH-sulfoximines
with
aryldiazonium
tetrafluoroborates
DABSO
toward
N-sulfonyl
sulfoximines
has
been
developed
under
mildly
basic
conditions.
This
transformation
features
easy
operation,
readily
available
substrates,
mild
A
tentative
mechanism
is
proposed,
which
indicates
that
the
would
be
radical
donors
standard
reaction
The
aryl
produced
in
situ
from
diazonium
salts
trapped
by
to
generate
an
arylsulfonyl
then
undergo
further
final
sulfoximines.
Dalton Transactions,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Natural
R
-carvone
was
converted
into
ruthenium
complexes
with
planar-chiral
arene
ligands.
Similar
to
the
classical
[(cymene)RuCl
2
]
complex,
they
catalyse
C–H
activation
reactions,
albeit
low
stereoselectivity.
A
concise
synthesis
of
benzodiazepines
via
Rh(III)
catalyzed
C-H
activation/
[4
+
3]
annulation
easily
available
1-arylpyrazolidinones
with
allylic
acetal
has
been
developed.
The
was
employed
as
a
novel
3C
synthon
in
this
transformation.
Benzodiazepines
were
built
under
mild
reaction
conditions
high
efficiency
and
chemoselectivity.
atom-economy
accessible
substrates
reveal
potential
application.
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 11, 2025
Herein,
we
reported
a
DBU-catalyzed
cascade
and
sequential
[1
+
2
3]
annulation
of
malononitrile
with
α,β-unsaturated
ketones
to
access
polyfunctionalized
cyclohexanes
high
yield
excellent
diastereoselectivity
(>93%
yield,
>19:1
dr).
Intriguingly,
this
appears
be
the
new
strategy
for
using
either
as
2C
or
3C
synthon
react
dinucleophile
1C
construct
six-membered
carbocycles
in
one-pot
manner.
In
addition,
these
synthesized
compounds
suppressed
growth
phytopathogenic
fungi
vitro.
Among
them,
compound
3l
exhibited
broad
antifungal
activity,
which
possesses
potential
an
agricultural
agent.
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(5), С. 3345 - 3358
Опубликована: Фев. 19, 2024
In
this
study,
a
modular
approach
toward
cyclic
sulfoximines
and
sulfondiimines
via
palladium-catalyzed
intramolecular
C-H/C-C
activation
reactions
was
reported.
Various
1,2-benzothiazines
including
bicyclic,
tricyclic,
highly
fused
ones,
ones
of
the
seven-membered
ring,
along
with
1,2-benzothiazine
1-imines
were
accessed
in
good
yields.
KIE
experiment
demonstrated
that
C-H
bond
cleavage
at
position
Organic Letters,
Год журнала:
2024,
Номер
26(9), С. 1914 - 1919
Опубликована: Фев. 29, 2024
A
catalytic
kinetic
resolution
of
sulfoximines
has
been
developed
through
chiral
phosphoric
acid-catalyzed
intramolecular
dehydrative
cyclizations.
variety
racemic
bearing
an
ortho-amidophenyl
moiety
underwent
asymmetric
cyclizations
using
this
method,
yielding
both
the
recovered
and
benzothiadiazine-1-oxide
products
with
good
to
high
enantioselectivities
(with
s-factor
up
61).
The
diverse
derivatizations
into
a
wide
range
S-stereogenic
center-containing
S,N-heterocycles
have
demonstrated
value
method.
Angewandte Chemie International Edition,
Год журнала:
2024,
Номер
63(20)
Опубликована: Март 19, 2024
Abstract
Herein,
multiple
types
of
chiral
Os(II)
complexes
have
been
designed
to
address
the
appealing
yet
challenging
asymmetric
C(sp
3
)−H
functionalization,
among
which
Os(II)/Salox
species
is
found
be
most
efficient
for
precise
stereocontrol
in
realizing
amidation.
As
exemplified
by
enantioenriched
pyrrolidinone
synthesis,
such
tailored
catalyst
efficiently
enables
an
intramolecular
site‐/enantioselective
amidation
γ‐position
dioxazolone
substrates,
benzyl,
propargyl
and
allyl
groups
bearing
various
substituted
forms
are
well
compatible,
affording
corresponding
γ‐lactam
products
with
good
er
values
(up
99
:
1)
diverse
functionality
(>35
examples).
The
unique
performance
advantage
developed
system
terms
catalytic
energy
profile
induction
has
further
clarified
integrated
experimental
computational
studies.
Organic Letters,
Год журнала:
2024,
Номер
26(27), С. 5670 - 5675
Опубликована: Июнь 26, 2024
Axially
chiral
carboxylic
acids
are
important
motifs
in
catalysts
and
ligands.
We
herein
reported
the
synthesis
of
axially
via
Pd(II)-catalyzed
atroposelective
C-H
olefination
using
acid
as
native
directing
group.
A
broad
range
axial
biaryl-2-carboxylic
were
synthesized
good
yields
with
high
enantioselectivities
(up
to
84%
yield
99%
ee).
Gram-scale
reaction
further
transformation
reactions
also
provide
a
platform
for
synthetic
applications
this
method.
Applied Organometallic Chemistry,
Год журнала:
2025,
Номер
39(6)
Опубликована: Май 2, 2025
ABSTRACT
2‐Aryl‐
4H
‐benzo[
d
][
1
,
3
]oxazin‐
4
‐one
derivatives
can
be
directly
alkenylated
with
alkyl
acrylates
using
a
facile
Ru
(II)‐catalyzed
process;
Cu
(OAc)
2
•H
O
as
an
oxidizer
through
formation
of
pentagon
cyclic
complex
imine‐Ru
(II)
for
C–H
activation
is
described.
The
unique
catalytic
reaction
well
matched
miscellaneous
olefins
such
vinyl
ketones,
acrylonitrile,
and
acrylates.
aryl
rings
bearing
electronically
diverse
substituents
tolerated
the
conditions
to
provide
ortho‐alkenylation
products
in
high
regioselectivities
admissible
yields.
