Langmuir, Год журнала: 2025, Номер unknown

Опубликована: Апрель 4, 2025

Ocular lubrication is a critical component of the biological system. Factors such as tear film instability and corneal epithelial damage can lead to increased friction on ocular surface during blinking, which negatively impacts quality life results in economic burden. Eye drops are commonly used therapeutic purposes. Due frequent movement (blinking, secretion, nasolacrimal drainage), their bioavailability low, requiring applications. In this study, methacylated gellan gum (GGMA) hydrogels were synthesized using methacrylic anhydride low-acyl raw materials. The elastic modulus GGMA hydrogel nearly threefold after introduction alkali metal ions. Macroscopic superlubricity was achieved experiments simulating environment. At contact pressure close 10 kPa, COF reduced 0.004. Detailed sophisticated simulations revealed underlying mechanism, showing that attributed hydration properties ions adsorbed onto surface. exhibits excellent lubricating properties, offering promising potential for enhancing supporting eye health.

Язык: Английский