Advanced Functional Materials,
Год журнала:
2023,
Номер
33(39)
Опубликована: Март 9, 2023
Abstract
Stimuli‐responsive
hydrogels
have
attracted
much
attention
owing
to
the
versatility
of
their
programmed
response
in
offering
intelligent
solutions
for
biomimicry
applications,
such
as
soft
robotics,
tissue
engineering,
and
drug
delivery.
To
achieve
complexity
biomimetic
structures,
two
photon
polymerization
(2PP)
has
provided
a
means
fabricating
intricate
3D
structures
from
stimuli‐responsive
hydrogels.
Rapid
swelling
hydrogel
microstructures
are
advantageous
osmotically
driven
stimuli‐response,
where
actuation
speed,
that
is
reliant
on
diffusion
analytes
or
bioanalytes,
can
be
optimized.
Herein,
flexibility
2PP
exploited
showcase
novel
sugar‐responsive,
phenylboronic
acid‐based
photoresist.
This
offers
remarkable
solution
achieving
fast
systems
been
often
hindered
by
volume‐dependent
times
receptor
sites.
A
photoresist
compatible
with
presented
fabricate
accelerated
times.
Moreover,
programmable
(i.e.,
bending
opening)
fabricated
using
same
within
one‐step
fabrication
process.
By
combining
an
easily
adaptable
photoresist,
accessible
method
showcased
sophisticated
chemo‐responsive
actuators.
Advanced Materials Interfaces,
Год журнала:
2023,
Номер
10(6)
Опубликована: Янв. 22, 2023
Abstract
The
wettability
and
adhesion
of
biological
surfaces
often
depend
on
their
periodically
arranged
hybrid
micro–nano
array
structures.
Various
fabrication
processes
are
designed
to
mimic
biomimetic
surfaces.
This
review
summarizes
the
types
structures
analyzes
methods
based
top‐down
bottom‐up
construction,
including
templating,
etching,
self‐assembly,
electrospinning/electrospraying.
focuses
shape
reconfiguration
surface
under
physical
stimuli,
as
well
changes
in
material
properties
during
process.
In
addition,
applications
composite
fields
droplet
transport,
properties,
sensors,
soft
robotics
also
discussed,
current
challenges
prospects
this
field
identified.
Nature Communications,
Год журнала:
2023,
Номер
14(1)
Опубликована: Июль 17, 2023
Inspired
by
the
flexible
joints
of
humans,
actuators
containing
soft
have
been
developed
for
various
applications,
including
grippers,
artificial
muscles,
and
wearable
devices.
However,
integrating
multiple
microjoints
into
robots
at
micrometer
scale
to
achieve
multi-deformation
modalities
remains
challenging.
Here,
we
propose
a
two-in-one
femtosecond
laser
writing
strategy
fabricate
composed
hydrogel
metal
nanoparticles,
develop
multi-joint
microactuators
with
(>10),
requiring
short
response
time
(30
ms)
low
actuation
power
(<10
mW)
deformation.
Besides,
independent
joint
deformation
control
linkage
deformation,
co-planar
spatial
linkage,
enables
microactuator
reconstruct
variety
complex
human-like
modalities.
Finally,
as
proof
concept,
collection
microcargos
different
locations
is
achieved
double-joint
micro
robotic
arm.
Our
will
bring
many
potential
application
opportunities
in
microcargo
collection,
microfluid
operation,
cell
manipulation.
Abstract
Stimuli‐responsive
fluorescent
hydrogels
are
three‐dimensional
networked
polymeric
materials
with
tunable
luminescence
and
dynamic
properties,
which
play
an
important
role
as
a
water‐rich
soft
material
in
the
fields
of
information
encryption,
bionic
actuation,
bioimaging,
environmental
monitoring,
luminescent
materials.
Compared
conventional
hydrogels,
their
unique
properties
allow
visualization
microscopic
dynamics
within
polymer
network.
By
rational
inclusion
motifs,
such
photoswitches,
AIEgens,
lanthanide
complexes,
host–guest
these
endowed
tunability
emission,
shape,
phase
time
space
response
to
effectors.
In
this
review,
we
summarize
fabrication
strategies
that
mainly
used
by
recently
reported
stimuli‐responsive
applications
ACS Nano,
Год журнала:
2020,
Номер
14(7), С. 8409 - 8420
Опубликована: Июнь 10, 2020
Recently,
a
great
deal
of
research
has
focused
on
the
study
self-healing
hydrogels
possessing
electronic
conductivity
due
to
their
wide
applicability
for
use
in
biosensors,
bioelectronics,
and
energy
storage.
The
low
solubility,
poor
biocompatibility,
lack
effective
stimuli-responsive
properties
sp2
carbon-rich
hybrid
organic
polymers,
however,
have
proven
challenging
electroconductive
hydrogel
fabrication.
In
this
study,
we
developed
electrochemical
wireless
biosensors
using
ureidopyriminone-conjugated
gelatin
(Gel-UPy)
that
incorporate
diselenide-containing
carbon
dots
(dsCD)
cancer
detection.
cleavage
diselenide
groups
dsCD
within
by
glutathione
(GSH)
or
reactive
oxygen
species
(ROS)
initiates
formation
hydrogen
bonds
affect
ability,
conductivity,
adhesiveness
Gel-UPy/dsCD
hydrogels.
demonstrate
more
rapid
healing
under
tumor
conditions
(MDA-MB-231)
compared
observed
physiological
(MDCK).
Additionally,
affects
signals
degradation
dsCD.
also
exhibit
excellent
vivo
detection
ability
after
exposure
high
concentration
GSH
ROS,
is
comparable
results
environment.
Based
combined
self-healing,
Gel-UPy/dsCD,
exhibits
promise
biomedical
applications,
particularly
those
involve
detection,
its
selectivity
sensitivity
conditions.
Nanotechnology Reviews,
Год журнала:
2020,
Номер
9(1), С. 1118 - 1136
Опубликована: Янв. 1, 2020
Abstract
Micro/nano-fabrication
technology
via
two-photon
polymerization
(TPP)
nanolithography
is
a
powerful
and
useful
manufacturing
tool
that
capable
of
generating
two
dimensional
(2D)
to
three
(3D)
arbitrary
micro/nano-structures
various
materials
with
high
spatial
resolution.
This
has
received
tremendous
interest
in
cell
tissue
engineering
medical
microdevices
because
its
remarkable
fabrication
capability
for
sophisticated
structures
from
macro-
nano-scale,
which
are
difficult
be
achieved
by
traditional
methods
limited
microarchitecture
controllability.
To
fabricate
precisely
designed
3D
biomedical
applications
TPP
nanolithography,
the
use
photoinitiators
(PIs)
photoresists
needs
considered
comprehensively
systematically.
In
this
review,
widely
used
commercially
available
PIs
first
discussed,
followed
elucidating
synthesis
strategies
water-soluble
initiators
applications.
addition
conventional
photoresists,
distinctive
properties
customized
stimulus-responsive
discussed.
Finally,
current
limitations
challenges
material
aspects
an
outlook
future
prospects
based
on
different
biocompatible
photosensitive
composites
discussed
comprehensively.
all,
review
provides
basic
understanding
important
roles
fabricating
high-precision
wide
range
ACS Nano,
Год журнала:
2021,
Номер
15(3), С. 5118 - 5128
Опубликована: Март 9, 2021
Micro-
and
nanomachines
as
feasible
agents
to
exploit
the
microworld
have
attracted
extensive
research
interest,
particularly
in
manipulation
of
soft
nanorobots
at
small
scales.
Herein,
we
propose
a
model
for
regulating
motion
swinging
flexible
nanomotor
(SFN)
driven
by
an
oscillating
magnetic
field.
Multisegments
SFN
are
synthesized
from
nickel,
gold,
porous
silver.
The
coupling
actuation
pattern
SFNs
studied
reveal
their
mobility.
Additionally,
optimal
frequency
occurs
torque
structural
deformation,
rather
than
simply
considered
step-out
phenomenon.
Meanwhile,
fluidic
trapping
region
is
formulated
alongside
SFN.
Such
demonstrated
living
neutrophil
accomplishing
vitro
transportation
using
mediation.
On-demand
cargo
delivery
can
be
realized
programmable
field,
recycled
with
ease
after
owing
environmental
concerns.
In
this
study,
properties
that
useful
bases
customization
control.
These
nanomotors
may
potential
promote
drug
biomedical
operations
noncontact
modes.
Chemical Science,
Год журнала:
2021,
Номер
12(19), С. 6472 - 6487
Опубликована: Янв. 1, 2021
Shape
deformation
hydrogels,
which
are
one
of
the
most
promising
and
essential
classes
stimuli-responsive
polymers,
could
provide
large-scale
reversible
under
external
stimuli.
Cyborg and Bionic Systems,
Год журнала:
2022,
Номер
2022
Опубликована: Янв. 1, 2022
The
rapid
development
of
medical
micromotors
draws
a
beautiful
blueprint
for
the
noninvasive
or
minimally
invasive
diagnosis
and
therapy.
By
combining
stimuli-sensitive
hydrogel
materials,
are
bestowed
with
new
characteristics
such
as
stimuli-responsive
shape
transformation/morphing,
excellent
biocompatibility
biodegradability,
drug
loading
ability.
Actuated
by
chemical
fuels
external
fields
(e.g.,
magnetic
field,
ultrasound,
light,
electric
field),
hydrogel-based
(HBSR)
can
be
utilized
to
load
therapeutic
agents
into
networks
directly
grip
target
cargos
drug-loaded
particles,
cells,
thrombus),
transport
them
sites
interest
tumor
area
diseased
tissues),
unload
execute
specific
task
cell
capture,
targeted
sampling,
removal
blood
clots)
in
response
stimulus
change
temperature,
pH,
ion
strength,
chemicals)
physiological
environment.
high
flexibility,
adaptive
capacity,
morphing
property
enable
HBSR
complete
tasks
complex
scenarios,
especially
confined,
hard-to-reach
tissues,
vessels
body.
Herein,
this
review
summarizes
current
progress
stimuli
responsiveness.
thermo-responsive,
photothermal-responsive,
magnetocaloric-responsive,
pH-responsive,
ionic-strength-responsive,
chemoresponsive
discussed
detail.
Finally,
challenges
future
perspectives
biomedical
field
discussed.
