Biomaterials, Год журнала: 2025, Номер 318, С. 123138 - 123138
Опубликована: Янв. 28, 2025
Язык: Английский
Advanced Materials, Год журнала: 2024, Номер 36(32)
Опубликована: Июнь 14, 2024
Abstract Nanomedicine on the basis of aggregated‐induced emission (AIE) luminogens with exceptional potency is growing into a sparkling frontier in fluorescence imaging and phototheranostics. Of particular interest biomimetic AIE nanomedicine comprised by biocarrier, which represents win–win integration are recently developed at tremendous pace, mainly benefiting from intrinsic advantages including enhanced biocompatibility, prolonged circulation time, specific targeting ability, immune activation, supremely extraordinary phototheranostic outputs. In view inexhaustible vigorous vitality field, this review provides an integrated picture involving basic concepts, significant breakthroughs, recent trends. addition, based current achievements, some critical challenges perspectives also discussed.
Язык: Английский
Процитировано
23
Aggregate, Год журнала: 2024, Номер 5(3)
Опубликована: Янв. 31, 2024
Abstract Aggregation‐induced emission (AIE) is an intriguing photophysical phenomenon, where specific materials exhibit a remarkable surge in luminescence when brought together non‐ideal solvents or within solid matrix. Since the concept of AIE was first introduced 2001, numerous advanced applications have been gradually explored across various domains, including optics, electronics, energy, and life sciences. Of particular note growing interest application systems with near‐infrared (NIR) emissive feature field biomedicine, encompassing detection, imaging, therapeutic interventions. Notably, bibliometric analysis serves as valuable tool to provide researchers comprehensive understanding research achievements developmental trends fields, which crucial for academic research. Herein, we present general overview spanning two decades NIR‐AIE development. With assistance core scientific databases software tools, conducted systematic annual publications citations, most influential countries/regions, leading authors, journals, institutions, well hot topics related NIR forward‐looking predictions. Furthermore, properties biomedical also systematically reviewed.
Язык: Английский
Процитировано
17
Pharmaceutics, Год журнала: 2024, Номер 16(4), С. 531 - 531
Опубликована: Апрель 12, 2024
Nanoparticle-based drug delivery systems hold promise for cancer treatment by enhancing the solubility and stability of anti-tumor drugs. Nonetheless, challenges inadequate targeting limited biocompatibility persist. In recent years, cell membrane nano-biomimetic have emerged as a focal point research development, due to their exceptional traits, including precise targeting, low toxicity, good biocompatibility. This review outlines categorization advantages bionic nano-delivery systems, provides an introduction preparation methods, assesses applications in treatment, chemotherapy, gene therapy, immunotherapy, photodynamic photothermal combination therapy. Notably, delves into application various identifies opportunities future advancement. Embracing membrane-coated biomimetic nanoparticles presents novel unparalleled avenue personalized tumor
Язык: Английский
Процитировано
17
Materials Today Bio, Год журнала: 2025, Номер 30, С. 101443 - 101443
Опубликована: Янв. 5, 2025
Glioblastoma (GBM) is the most prevalent primary malignant brain tumor, characterized by a high mortality rate and poor prognosis. The blood-brain barrier (BBB) blood-tumor (BTB) present significant obstacles to efficacy of tumor-targeted pharmacotherapy, thereby impeding therapeutic potential numerous candidate drugs. Targeting delivery adequate doses drug across BBB treat GBM has become prominent research area in recent years. This emphasis driven exploration evaluation diverse technologies for with some already undergoing clinical trials. review provides thorough overview advancements challenges targeted treatment. It specifically emphasizes systemic administration strategies assess their limitations Furthermore, this highlights promising future directions development intelligent systems aimed at overcoming current enhancing against GBM. These not only support foundational on but also offer methodological approaches applications.
Язык: Английский
Процитировано
3
Biomaterials, Год журнала: 2025, Номер 318, С. 123138 - 123138
Опубликована: Янв. 28, 2025
Язык: Английский
Процитировано
2