Nanomaterial-mediated self-calibrating biosensors for ultra-precise detection of food hazards: Recent advances and new horizons

Coordination Chemistry Reviews, Год журнала: 2024, Номер 522, С. 216204 - 216204

Опубликована: Сен. 10, 2024

Язык: Английский

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Carbon Dots with Integrated Photothermal Antibacterial and Heat‐Enhanced Antioxidant Properties for Diabetic Wound Healing

Small, Год журнала: 2024, Номер 20(45)

Опубликована: Июль 25, 2024

Abstract Diabetic wounds pose a persistent challenge due to their slow healing nature, primarily caused by bacterial infection and excessive reactive oxygen species (ROS)‐induced inflammation. In this study, carbon dots with synergistic antibacterial antioxidant properties, referred as AA‐CDs, are developed specifically for diabetic wound using straightforward solvothermal method. By utilizing cost‐effective precursors like citric acid ascorbic acid, AA‐CDs engineered possess tailored functions of photothermal sterilization ROS scavenging. The resulting demonstrats broad‐spectrum activity, particularly against multidrug‐resistant strains, along efficient scavenging both in solution within cells. Additionally, exhibits protective effect oxidative stress‐induced damage. Notably, high conversion efficiency (41.18%), displays heat‐enhanced performance, providing not only augmented but also additional protection stress, yielding true “1 + 1 > 2” effect. To facilitate use vivo, incorporated into thermally responsive hydrogel, which evident anti‐inflammatory properties modulating inflammatory factors significantly promots the wounds. This study underscores value integrated platforms highlights potential versatile CDs promising therapeutic agents biomedical applications.

Язык: Английский

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Exchange-coupled bi-magnetic nanoparticles enhance magnetothermal/chemodynamic antibacterial therapy of poly-l-lactide scaffold

Journal of Colloid and Interface Science, Год журнала: 2025, Номер 685, С. 1131 - 1142

Опубликована: Янв. 22, 2025

Язык: Английский

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A Fluorescence/Colorimetric Synergistic‐Enhanced Type‐I Heterostructured MOF@QDs for Both Multi‐Depth Food‐Freshness Prediction and Extra Preservation

Small, Год журнала: 2025, Номер unknown

Опубликована: Фев. 13, 2025

Abstract Spoiled food has significantly impacted the global economy and public health, which increases worldwide concern about monitoring preserving freshness. Herein, a multi‐functional type‐I heterojunction (Eu@ZMC) is designed by europium metal‐organic framework (EuMOF), zinc oxide quantum dots (ZnO QDs), chlorogenic acid (CGA). Eu@ZMC achieves ratiometric fluorescent/colorimetric sensing of pH biogenic amines to detect Besides, paper‐based platform (PEu@ZMC) prepared can histamine with LOD 0.0142 0.0136 µg mL −1 in fluorescent colorimetric modes, respectively. An advanced OR/NOT‐gate logic device further constructed distinguish freshness into three levels (fresh, less fresh, spoiled). This dual‐mode sensor synergistic‐enhanced energy transfer triggered ZnO QDs‐promoted colorimetry heterostructure EuMOF QDs. The release low‐toxic ions inhibits various bacterial growth, including Salmonella typhimurium . According raw fish evaluation, not only effectively monitors spoilage externally internally aligning commercial kit, but also reduces speed, cannot be achieved through classical detection strategy. original work provides simple, convenient, reliable method for multi‐depth real‐time visual extract preservation, contributing economic benefits human health assurance.

Язык: Английский

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Quantum dots: a next generation approach for pathogenic microbial biofilm inhibition; mechanistic insights, existing challenges, and future potential

Archives of Microbiology, Год журнала: 2024, Номер 206(4)

Опубликована: Март 13, 2024

Язык: Английский

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NIR light-activated nanocomposites combat biofilm formation and enhance antibacterial efficacy for improved wound healing

Communications Chemistry, Год журнала: 2024, Номер 7(1)

Опубликована: Июнь 8, 2024

Abstract Nanoparticle-based therapies are emerging as a pivotal frontier in biomedical research, showing their potential combating infections and facilitating wound recovery. Herein, selenium-tellurium dopped copper oxide nanoparticles (SeTe-CuO NPs) with dual photodynamic photothermal properties were synthesized, presenting an efficient strategy for bacterial infections. In vitro evaluations revealed robust antibacterial activity of SeTe-CuO NPs, achieving up to 99% eradication bacteria significant biofilm inhibition upon near-infrared (NIR) irradiation. Moreover, vivo studies demonstrated accelerated closure treatment NIR-activated demonstrating efficacy promoting healing. Furthermore, NPs exhibited rapid clearance within wounds, offering promising solution care. Overall, this versatile platform holds great promise multidrug-resistant advancing therapeutic interventions management.

Язык: Английский

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Phenylboronic Acid-Modified Carbon Dot-Proteinase K Nanohybrids for Enhanced Photodynamic Therapy Against Bacterial Biofilm Infections

Acta Biomaterialia, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Zinc Cerium Peroxide Antibacterial Agent with Acid-Activated Cascade Multienzymatic Activities

ACS Applied Nano Materials, Год журнала: 2025, Номер unknown

Опубликована: Фев. 2, 2025

Recently, metal peroxides with the ability to self-supply H2O2 have been intensively used in antibacterial and cancer therapy. However, performances are unsatisfactory due low efficiency of peroxide-mediated Fenton-like reaction. In this work, a novel zinc cerium bimetallic peroxide (CeZnOx) has first reported, which possesses acid-activated POD-like, OXD-like, CAT-like multienzymatic activities for efficiently bacterial inhibition. Specifically, CeZnOx self-supplying under weakly acidic conditions subsequently catalyzes production reactive oxygen species (ROS) through synergistically enhanced POD-like OXD-like activity. They can also exhibit activity catalyze excessive into O2 play an anti-inflammatory role normal pH conditions. The cascade inhibit growth alleviate hypoxia, improving microenvironment at wound site. As expected, exhibits superior effect on Staphylococcus aureus Escherichia coli. Therefore, CeZnOx-mediated offer simple promising strategy efficient treatment infections.

Язык: Английский

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Multipurpose β-Cyclodextrin-Involved nanospherical Aggregates: Self-Assembly Process, foliar Adhesion, and promising applications for kiwifruit and rice Protections

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 160385 - 160385

Опубликована: Фев. 1, 2025

Язык: Английский

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Facile One‐Pot Assembly of a Versatile Photoactive Nanozyme for Highly Efficient Antibacterial Therapy

Small, Год журнала: 2025, Номер unknown

Опубликована: Март 16, 2025

Abstract Conventional combinational antibacterial therapy requires the complicated assembly of multiple components that might cause a premature leak therapeutic agents. Thus one‐pot highly integrated multifunctional agents is desirable for treating multidrug‐resistant (MDR) bacteria. Herein, vancomycin‐derived carbon dots (Van‐CDs) are facilely developed as compact and powerful photodynamic nanozyme platform achieves augmented reactive oxygen species (ROS) generation accelerating bacterial elimination. By residual recognition groups vancomycin, red emissive Van‐CDs gain specific affinity toward bacteria with high binding constant 20 L g −1 , manifesting superior bacteria‐imaging ability. Meanwhile, encoded an excellent peroxidase‐mimicking (POD) activity mediating H 2 O ‐activated evolvement •OH, also endowed intrinsic property simultaneously producing singlet ( 1 ). Surprisingly, possesses auxiliary photothermal feature, which enables imaging‐guided hyperthermia‐reinforced in vivo. Furthermore, subcutaneous abscess model established to validate their pronounced biofilm eradication wound healing acceleration vivo through Van‐CDs‐promoted collagen deposition. Taken together, present all‐in‐one carbon‐derived functions represents promising competitive candidate diabetic infections clinical research.

Язык: Английский

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