Enhanced mechanical properties of cellulose fiber networks through synergistic effects of telechelic-structured carbohydrate-binding module-modified amphoteric polyacrylamide

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 140771 - 140771

Опубликована: Фев. 1, 2025

Язык: Английский

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Bisphenol A-Induced Cancer-Associated Adipocytes Promotes Breast Carcinogenesis Via CXCL12/AKT Signaling

Molecular and Cellular Endocrinology, Год журнала: 2025, Номер unknown, С. 112473 - 112473

Опубликована: Янв. 1, 2025

Язык: Английский

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Industrial Kraft Lignin-Functionalized Cellulose Nanofluidic Membrane for Enhanced Osmotic Energy Conversion

ACS Applied Nano Materials, Год журнала: 2025, Номер unknown

Опубликована: Фев. 5, 2025

Язык: Английский

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Lignin-Based Nanoparticles for Combination of Tumor Oxidative Stress Amplification and Reactive Oxygen Species Responsive Drug Release

Bioconjugate Chemistry, Год журнала: 2024, Номер 35(8), С. 1207 - 1217

Опубликована: Июль 11, 2024

In this study, maleic anhydride-modified lignin (LG-M), a ROS-cleavable thioketal (TK) bond, and polyethylene glycol (PEG) were used to synthesize lignin-based copolymer (LG-M(TK)-PEG). Doxorubicin (DOX) was attached the bond in LG-M(TK)-PEG for preparation of ROS-activatable DOX prodrug (LG-M(TK-DOX)-PEG). Nanoparticles (NPs) with size 125.7 ± 3.1 nm prepared by using LG-M(TK-DOX)-PEG, they exhibited enhanced uptake cancer cells compared free DOX. Notably, presence nanoparticles could boost ROS production breast 4T1 while showing little effect on L929 normal cells. This selective facilitated specific activation tumor microenvironment, resulting superior inhibitory effects biosafety relative work demonstrates potential LG-M(TK-DOX)-PEG NPs as an efficient drug delivery system treatment.

Язык: Английский

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Multi‐Solvent‐Induced Gradient Aggregation Rendered Superstrong, Tough, Stretchable, and Fatigue‐Resistant Lignin‐Based Supramolecular Hydrogels

Advanced Functional Materials, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 16, 2024

Abstract A hydrogel that is expected as a biomedical load‐bearing material remains substantial challenge. In this work, multi‐solvent‐induced gradient aggregation state strategy developed to construct lignin‐based supramolecular hydrogels feature superstrong, tough, stretchable, and fatigue‐resistant properties. The multi‐solvent high‐temperature annealing induces the crystallization of polyvinyl alcohol self‐assembly lignin. interior strong hydrogen‐binding external weak non‐covalent‐binding forms microstructure compact macrostructure, where lignin acts an interfacial molecular bridge. By sharing interconnection points collaboratively dissipate energy, demonstrate high modulus (74.4 MPa), toughness (90 MJ m −3 ), tear (34,000 J −2 tensile (24.8 compressive strength (60 MPa). Moreover, such also exhibit extraordinary fatigue resistance, biocompatibility, reactive oxygen species scavenging activity. This non‐covalent conjoined‐network caused by provides new design potential for developing biomaterials mimic materials (e.g., natural tendons ligaments).

Язык: Английский

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Simple theranostics nanoagent for precision suppression of tumor growth and Metastasis: A traditional fermented product having a novel functional breakthrough

Chemical Engineering Journal, Год журнала: 2024, Номер 500, С. 156545 - 156545

Опубликована: Окт. 10, 2024

Язык: Английский

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Versatile Carrier-Free Binary Nanodrugs Based on Metformin/Epigallocatechin Gallate Nanoparticles: Exploring Its Properties and Potential in Cancer Treatment†

Biomaterials Science, Год журнала: 2024, Номер unknown

Опубликована: Дек. 20, 2024

Epigallocatechin gallate (EGCG), an important active component extracted from green tea, has attracted much attention due to its multiple biological activities such as antioxidant, antibacterial, anti-inflammatory, and antitumor effects.

Язык: Английский

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