International Journal of Chemical Engineering,
Год журнала:
2024,
Номер
2024, С. 1 - 13
Опубликована: Фев. 28, 2024
This
investigation
focused
on
assessing
and
enhancing
ultrasound-assisted
extraction
(UAE)
using
natural
deep
eutectic
solvents
(NADES)
to
extract
phenolics
terpenoids
from
sweet
basil
leaves.
The
initial
stage
involved
evaluating
the
performance
of
twelve
NADES
ethanol.
A
comprising
lactic
acid
glucose
with
a
2
:
1
molar
ratio
20%
water
content
(WC)
obtained
highest
total
phenolic
(TPC)
terpenoid
(TTC).
Single-factor
experiments
systematically
examined
impact
liquid-to-solid
(LSR),
in
(WC),
ultrasound
power,
temperature,
exposure
time
yield.
Optimization
Box–Behnken
Design
(BBD)
models
for
glucose-based
UAE
revealed
optimal
conditions
be
80
ml/g
LSR,
30%
water,
300
W,
50°C
15-minute
time.
Under
these
optimized
parameters,
achieved
TPC
TTC
at
69.88
mg
GAE/g
110.71
UA/g,
respectively.
study
presents
an
environmentally
friendly
sustainable
protocol
compounds
Molecules,
Год журнала:
2025,
Номер
30(2), С. 284 - 284
Опубликована: Янв. 13, 2025
Essential
oils
(EOs)
are
highly
valued
in
the
cosmetic
and
food
industries
for
their
diverse
properties.
However,
traditional
extraction
methods
often
result
low
yields,
inconsistent
compositions,
lengthy
times,
use
of
potentially
harmful
solvents.
Natural
deep
eutectic
solvents
(NADES)
have
emerged
as
promising
alternatives,
offering
advantages
such
higher
efficiency,
cost-effectiveness,
biodegradability,
tunable
This
review
explores
application
NADES
enhancing
EO
extraction,
focusing
on
current
methodologies,
key
insights,
practical
applications.
It
examines
factors
that
influence
with
NADES,
including
optimization
physicochemical
properties,
techniques,
operational
conditions,
role
sample
pretreatment
improving
efficiency.
Additionally,
this
covers
chemical
characterization
biological
activities
EOs
extracted
using
NADES.
By
providing
a
comprehensive
overview,
it
highlights
potential
to
improve
suggests
directions
future
research
field.
Pharmaceuticals,
Год журнала:
2024,
Номер
17(3), С. 355 - 355
Опубликована: Март 9, 2024
The
methods
and
solvents
employed
in
routine
extraction
protocols
essentially
impact
the
composition
of
resulting
extracts,
i.e.,
relative
abundances
individual
biologically
active
metabolites
quality
stability
isolates.
Natural
deep
eutectic
(NADESs)
represent
a
new
class
environmentally
friendly
solvents,
which
are
recognized
as
promising
extractants
alternative
to
conventional
organic
liquids.
However,
their
efficiencies
when
applied
different
workflows
still
poorly
characterized.
Therefore,
here,
we
compare
potential
three
for
natural
products
from
Aralia
elata
var.
mandshurica
with
selected
using
non-targeted
metabolomics
approach.
metabolite
profiling
relied
on
reversed-phase
ultra-high-performance
liquid
chromatography–high-resolution
mass
spectrometry
(RP-UHPLC-HR-MS).
roots
A.
were
extracted
by
maceration,
ultrasound-assisted
(UAE),
vibrocavitation-assisted
(VAE).
Principal
component
analysis
(PCA)
revealed
clear
separation
extracts
obtained
NADES1
(choline
chloride/malic
acid)
NADES2
(sorbitol/malic
acid/water).
Based
results
hierarchical
clustering
normalized
further
statistical
evaluation
t-test,
it
could
be
concluded
that
showed
superior
efficiency
all
addressed.
this
NADES
was
more
detail.
PCA
followed
t-test
yielded
only
3
efficiently
whereas
46
compounds
abundant
VAE.
When
VAE
UAE
compared,
108
appeared
VAE,
1
recovered
UAE.
These
facts
clearly
indicate
advantage
method
over
maceration
Seven
twenty-seven
tentatively
identified
tandem
(MS/MS)
found
first
time.
Additional
studies
necessary
understand
applicability
other
plant
materials.
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(13), С. 6879 - 6879
Опубликована: Июнь 22, 2024
Phytopathogenic
fungi
are
responsible
for
diseases
in
commercially
important
crops
and
cause
major
supply
problems
the
global
food
chain.
Plants
were
able
to
protect
themselves
from
disease
before
humans
played
an
active
role
protecting
plants.
They
known
synthesize
a
variety
of
secondary
metabolites
(SMs),
such
as
terpenes,
alkaloids,
phenolic
compounds,
which
can
be
extracted
using
conventional
unconventional
techniques
formulate
biofungicides;
plant
extracts
have
antifungal
activity
various
mechanisms
action
against
these
organisms.
In
addition,
they
considered
non-phytotoxic
potentially
effective
control.
sustainable
economically
viable
alternative
use
agriculture,
is
why
biofungicides
increasingly
recognized
attractive
option
solve
caused
by
synthetic
fungicides.
Currently,
organic
farming
continues
grow,
highlighting
importance
developing
environmentally
friendly
alternatives
crop
production.
This
review
provides
compilation
literature
on
biosynthesis,
phytopathogens,
extraction
formulation
biofungicides,
biological
phytopathogenic
fungi,
regulation,
advantages,
disadvantages
overview
current
agriculture.
PLoS ONE,
Год журнала:
2024,
Номер
19(3), С. e0300969 - e0300969
Опубликована: Март 29, 2024
This
study
employed
novel
extraction
methods
with
natural
deep
eutectic
solvents
(NADES)
to
extract
bioactive
compounds
and
proteins
from
Bacopa
monnieri
leaves.
The
conditional
influence
of
ultrasonic-assisted
(UAE),
microwave-assisted
(MAE),
enzymatic-assisted
(EAE)
on
the
recovery
efficiency
phenolics,
proteins,
flavonoids,
terpenoids
was
evaluated.
conditions
UAE
were
50
mL/g
LSR,
600W
ultrasonic
power,
30%
water
content
40°C
for
1
min
obtain
highest
protein
contents.
MAE
40
400W
microwave
power
3
reach
contents
biological
compounds.
EAE
30
20
U/g
enzyme
concentration
L-Gly-Na
molar
ratio
at
2:4:1,
40%
60
acquire
compound
Scanning
electron
microscopy
(SEM)
is
analyze
surface
leaves
before
after
extraction.
Comparing
seven
conducted
find
most
favorable
ones.
result
showed
that
UMEAE
method
effective
way
exploit
suggested
effectively
extracts
terpenoids,
DBMP.
Applied Food Research,
Год журнала:
2024,
Номер
4(2), С. 100451 - 100451
Опубликована: Июль 24, 2024
The
aim
of
this
study
was
to
recover
bioactive
compounds
from
Smallanthus
sonchifolius
roots,
including
flavonoids,
terpenoids,
phenolics,
vitamin
C,
and
reducing
sugar
contents,
as
well
examine
antioxidant
activities
using
ultrasonic-assisted
microwave-assisted
extraction
technique.
Single-factor
experiments
were
employed
explore
the
impact
various
independent
variables,
concentration,
method,
power,
duration,
temperature,
pH,
on
dependent
variables
yacon
ultrasonic-microwave-assisted
method.
Plackett-Burman
Design
Model
used
screen
parameters
that
significantly
influenced
efficiency.
Box-Behnken
utilized
optimize
extracting
process
acquire
compounds.
highest
yield
total
flavonoid
contents
obtained
with
4.00
743.33
W
microwave
39.08°C
ultrasonic
temperature.
According
optimization,
optimum
conditions
3.98
36.17
seconds
time
40°C
To
C
optimized
1:40
g/mL
sample-to-solvent
ratio,
3.99
45.33
time,
451.09
power.
Regarding
terpenoids
yield,
for
2.48
30.49
49.48
°C
Under
conditions,
recovery
flavonoid,
terpenoid,
7.95
mg
rutin
equivalents/g,
47.93
ursolic
acid
107.78
ascorbic
acid/g,
230.39
D-glucose
respectively.
Ultrasonic-microwave-assisted
showed
higher
performance
than
singular
methods
is
regarded
a
sustainable
effective
approach
target
roots.
Molecules,
Год журнала:
2024,
Номер
30(1), С. 55 - 55
Опубликована: Дек. 27, 2024
Phenolic
compounds
present
in
plants
and
foods
are
receiving
increasing
attention
for
their
bioactive
sensory
properties,
accompanied
by
consumers’
interest
products
with
health
benefits
derived
from
natural
rather
than
artificial
sources.
This,
together
the
sustainable
development
goals
21st
century,
has
driven
of
green
extraction
techniques
that
allow
obtaining
these
safety
quality
required
to
be
applied
food,
cosmetic
pharmaceutical
industries.
Green
involves
practices
aiming
at
reducing
environmental
impact
preparation
processes,
based
on
using
or
less-polluting
solvents,
lower
energetic
requirements
shorter
times,
while
providing
greater
efficiency
recovery
target
compounds.
In
this
article,
principles
advances
produced
recent
years
regarding
isolation
polyphenols
plants,
food
waste
reviewed.
