Frontiers in Bioengineering and Biotechnology,
Год журнала:
2025,
Номер
13
Опубликована: Май 29, 2025
Carbon
dots
(CDs)
are
a
class
of
nanobiomaterials
with
significant
potential
in
bone
regeneration.
Their
excellent
biocompatibility,
tunable
fluorescence,
high
stability,
low
toxicity,
and
abundant
functional
groups
make
CDs
promising
candidates
for
efficient
drug
delivery
tissue
contribute
to
targeted
release,
enhance
osteogenic
differentiation,
interact
cellular
components
facilitate
formation.
Recent
research
highlights
the
roles
scaffold-based
approaches,
offering
controlled
real-time
bioimaging
capabilities.
This
review
provides
comprehensive
overview
regeneration,
focus
on
their
synthesis,
functionalization,
biomedical
applications.
It
begins
by
exploring
CD
synthesis
methods,
physicochemical
properties,
mechanisms
action.
Next,
it
discusses
CD-based
systems
applications
Finally,
challenges
future
perspectives
optimizing
enhanced
therapeutic
outcomes.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Ноя. 13, 2024
Abstract
Water-soluble
fluorescent
N-doped
carbon
quantum
dots
(N-CQDs)
were
hydrothermally
prepared
through
a
green
synthesis
route
using
castor
seeds
as
single
precursor
and
hydrothermal
method.
Several
experimental
techniques
have
been
used
to
characterize
synthesized
N-CQDs
confirm
their
structure
verify
applicability
in
cell
imaging
pH
sensing.
The
found
are
characterized
by
amorphous
nature
with
spherical
shape
an
average
particle
size
of
6.57
nm
revealed
from
XRD
TEM
measurements.
FTIR
results
reveal
the
presence
carboxylic
hydroxyl
functional
groups
on
surface
CQDs,
which
was
also
confirmed
XPS
analysis.
fluorescence
characterization
showed
blue
emission
excitation
dependence
good
photostability.
It
that
optimal
wavelengths
(λ
Ex
=
360)
Em
432)
nm,
respectively.
yield
(QY)
about
9.6%
at
optimum
wavelength
360
nm.
Moreover,
intensity
linear
values
ranges
3.5
−
7.5
8
12
well
high
sensitivity
for
slight
changes
values.
According
these
results,
two
sensors
created
based
acidic
basic
media.
obtained
zeta
potential
-21.86
mV
thus
excellent
stability
water.
derived
antimicrobial
activity
exhibits
low
cytotoxicity
WI-13
cells
IC
50
394.4
±
13.8
µg/mL.
this
study
demonstrated
can
be
sensing
materials.
On
other
hand,
they
promising
applications
imaging,
thermo-sensing
optoelectronics.
Polish Annals of Medicine,
Год журнала:
2025,
Номер
unknown, С. 1 - 8
Опубликована: Апрель 22, 2025
Introduction
The
study
examined
how
people
with
chicken
egg
allergies
react
to
vaccines
that
contain
egg-derived
components.
Aim
purpose
of
the
was
determine
reaction
an
organism
hypersensitivity
a
immunisation
body
drugs
this
allergen.
Material
and
methods
To
achieve
goal,
against
measles,
mumps,
rubella,
influenza,
chickenpox,
rabies,
yellow
fever
were
analysed.
Results
discussion
It
determined
these
patients
did
not
have
allergic
reaction,
since
finished
minimal
remnants
elements
cannot
cause
hypersensitivity,
but
it
is
worth
noting
such
vaccination
should
be
carried
out
in
hospital
setting.
Immunisation
diseases
as
influenza
chickenpox
safe
method
disease
prevention.
After
only
2
them
after
procedure
had
clinical
signs
developing
allergies,
form
lacrimation,
sneezing,
rhinitis,
which
3.5%.
Rabies,
fever,
can
so
alternative
used
case.
eggs
contraindication
influenza.
Conclusions
safe,
even
case
previous
anaphylactic
complication
contact
allergen
humans,
because
preparation
contains
remains
egg,
are
able
full-fledged
reaction.
