Enzyme
entrapment
in
hydro-ionic
liquid
gels
(HydrIL
gels)
was
explored
as
an
enzyme
immobilization
strategy.
The
phase
of
the
a
mixture
buffer
and
tributyl
methyl
phosphonium
alkanesulfonate
[P4441][RSO3]
ionic
liquids.
modifies
creating
more
“organic”
hydrophobic
microenvironment
around
enzyme.
In
esterification
secondary
alcohol
by
Candida
antarctica
Lipase
B,
20-fold
enhancement
final
substrate
conversion
achieved
using
HydrIL
gel
compared
to
standard
poly(acrylamide)
hydrogel.
Co-polymerization
matrix
with
acrylate
monomers
led
further
increases
reaction
rate.
A
CalB
reused
over
10
cycles,
achieving
consistent
performance
from
fifth
cycle.
IL
leaching
became
undetectable
third
Catalysis Today,
Год журнала:
2024,
Номер
432, С. 114595 - 114595
Опубликована: Фев. 20, 2024
Enzyme
entrapment
in
hydro-ionic
liquid
gels
(HydrIL
gels)
was
explored
as
an
enzyme
immobilization
strategy.
The
phase
of
the
a
mixture
buffer
and
tributyl
methyl
phosphonium
alkanesulfonate
[P4441][RSO3]
ionic
liquids.
modifies
creating
more
"organic"
hydrophobic
microenvironment
around
enzyme.
In
esterification
secondary
alcohol
by
Candida
antarctica
Lipase
B,
20-fold
enhancement
final
substrate
conversion
achieved
using
HydrIL
gel
compared
to
standard
poly(acrylamide)
hydrogel.
Co-polymerization
matrix
with
acrylate
monomers
led
further
increases
reaction
rate.
A
CalB
reused
over
10
cycles,
achieving
consistent
performance
from
fifth
cycle.
IL
leaching
became
undetectable
third
Abstract
Transparent
materials
are
widely
used
in
industries,
everyday
life,
and
scientific
activities.
The
development
of
new,
lightweight,
durable
artificial
transparent
is
a
challenge
synthetic
chemistry.
In
this
study,
supramolecular
approach
conceived
to
construct
glass.
Cyclodextrins
selected
as
the
building
blocks
for
fabrication
glass
via
noncovalent
polymerization.
newly
formed
displays
several
attractive
advantages,
including
good
thermal
processability,
high
mechanical
strength
dielectric
constant,
excellent
visible
light
transparency,
adhesion
performance.
Importantly,
structural
characteristics
long‐range
disorder
short‐range
order
observed
cyclodextrin
Here
new
strategy
presented
preparation
functionalization
low‐molecular‐weight
materials.
Abstract
The
entrapment
of
deep
eutectic
solvents
(DES)
and
systems
into
porous
scaffolds
renders
a
new
class
soft
nonvolatile
materials
called
eutectogels
that
have
recently
stepped
the
spotlight
in
different
areas
ranging
from
electronics
to
drug
delivery.
Recent
progress
use
DES
biocatalysis,
where
they
been
demonstrated
improve
substrate
supply,
conversion,
enzyme
stability,
has
opened
an
unparalleled
opportunity
exploit
merits
for
immobilizing
biological
catalysts.
resulting
functional
could
outperform
traditional
hydrogels
ionic
liquid
gels,
offering
fresh
perspectives
broaden
application
scope
many
enzymes.
In
this
perspective,
we
go
potential
as
innovative
support
biocatalytic
reactions
discuss
applications
these
show
plain
benefits
compared
materials.
Future
directions
newly
developed
technology
are
highlighted.
Advanced Functional Materials,
Год журнала:
2024,
Номер
34(46)
Опубликована: Авг. 13, 2024
Abstract
This
study
focuses
on
incorporating
liquid
molecules,
different
from
the
bulk
solution,
into
immobilized
enzyme
carrier
to
regulate
distribution
effect
and
diffusion‐limiting
impact
of
carrier's
microenvironment
for
substrates,
which
generally
is
difficult
achieve
due
instability
materials
with
inclusions.
A
freestanding
liquid‐holding
particle
carrier,
bi‐component
hydrophobic
ionic
gel
microspheres
poly
(glycidyl
methacrylate)
as
network
1‐butyl‐3‐methylimidazolium
hexafluorophosphate
dispersing
medium,
proposed,
stable
in
air
aqueous
can
extract
proteins
organic
small
molecules
its
interior
mobility
medium.
Horseradish
peroxidase
covalently
microspheres,
forming
a
compartment
microreactor.
The
microreactor
exhibits
superior
stability,
enzymatic
activity,
catalytic
performance
Basic
Orange
II
degradation
compared
free
liquid‐free
enzymes.
attributed
biocompatibility
liquid,
role
substrate
enrichment
interior,
rapid
mass
transfer
capability.
contribution
shows
effectiveness
regulating
offering
fresh
perspectives
strategies
technology.
