Chemical Society Reviews,
Год журнала:
2011,
Номер
40(4), С. 1976 - 1976
Опубликована: Янв. 1, 2011
In
this
critical
review,
the
strategic
and
economic
benefits
of
C-H
functionalization
logic
will
be
analyzed
through
lens
total
synthesis.
order
to
illustrate
dramatically
simplifying
effects
type
can
potentially
have
on
synthetic
planning,
we
take
reader
a
series
case
studies
in
which
it
has
already
been
successfully
applied.
first
section,
chronological
look
at
key
historical
syntheses
examined,
leading
into
modern
day
examples.
second
our
own
experience
with
applying
executing
synthesis
"mindset"
discussed
(114
references).
Chemical Reviews,
Год журнала:
2016,
Номер
116(17), С. 10075 - 10166
Опубликована: Июнь 10, 2016
In
this
review,
we
highlight
the
use
of
organic
photoredox
catalysts
in
a
myriad
synthetic
transformations
with
range
applications.
This
overview
is
arranged
by
catalyst
class
where
photophysics
and
electrochemical
characteristics
each
discussed
to
underscore
differences
advantages
type
single
electron
redox
agent.
We
both
net
reductive
oxidative
as
well
neutral
that
can
be
accomplished
using
purely
photoredox-active
catalysts.
An
basic
transfer
theory
presented
order
provide
comprehensive
guide
for
employing
manifolds.
Angewandte Chemie International Edition,
Год журнала:
2012,
Номер
51(36), С. 8960 - 9009
Опубликована: Авг. 6, 2012
Abstract
The
direct
functionalization
of
CH
bonds
in
organic
compounds
has
recently
emerged
as
a
powerful
and
ideal
method
for
the
formation
carbon–carbon
carbon–heteroatom
bonds.
This
Review
provides
an
overview
bond
strategies
rapid
synthesis
biologically
active
such
natural
products
pharmaceutical
targets.
Angewandte Chemie International Edition,
Год журнала:
2012,
Номер
51(21), С. 5062 - 5085
Опубликована: Май 9, 2012
In
2010,
Richard
Heck,
Ei-ichi
Negishi,
and
Akira
Suzuki
joined
the
prestigious
circle
of
Nobel
Laureate
chemists
for
their
roles
in
discovering
developing
highly
practical
methodologies
C-C
bond
construction.
From
original
contributions
early
1970s
landscape
strategies
methods
organic
synthesis
irreversibly
changed
modern
chemist,
both
academia
industry.
this
Review,
we
attempt
to
trace
historical
origin
these
powerful
reactions,
outline
developments
from
seminal
discoveries
leading
eminent
position
as
appreciated
applied
today.
Chemical Society Reviews,
Год журнала:
2011,
Номер
40(9), С. 4740 - 4740
Опубликована: Янв. 1, 2011
Functionalizing
traditionally
inert
carbon–hydrogen
bonds
represents
a
powerful
transformation
in
organic
synthesis,
providing
new
entries
to
valuable
structural
motifs
and
improving
the
overall
synthetic
efficiency.
C–H
bond
activation,
however,
often
necessitates
harsh
reaction
conditions
that
result
functional
group
incompatibilities
limited
substrate
scope.
An
understanding
of
mechanism
rational
design
experimental
have
led
significant
improvement
both
selectivity
applicability.
This
critical
review
summarizes
discusses
endeavours
towards
development
mild
activation
methods
wishes
trigger
more
research
this
goal.
In
addition,
we
examine
select
examples
complex
natural
product
synthesis
demonstrate
utility
functionalization
(84
references).
Chemical Society Reviews,
Год журнала:
2011,
Номер
40(10), С. 5068 - 5068
Опубликована: Янв. 1, 2011
The
direct
functionalization
of
heterocyclic
compounds
has
emerged
as
one
the
most
important
topics
in
field
metal-catalyzed
C–H
bond
activation
due
to
fact
that
products
are
an
synthetic
motif
organic
synthesis,
pharmaceutical
industry,
and
materials
science.
This
critical
review
covers
recent
progresses
on
regioselective
dehydrogenative
coupling
reaction
heteroarenes,
including
arylation,
olefination,
alkynylation,
amination/amidation
mainly
utilizing
transition
metal
catalysts
(113
references).
