Divergent Construction of Thiochromanes and N-Arylbutanamides via Arylthiodifluoromethyl Radical-Triggered Cascade of Alkenes

The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(18), С. 13279 - 13290

Опубликована: Авг. 31, 2023

A strategy utilizing silver-catalyzed oxidative decarboxylation radical cascade cyclization of arylthiodifluoroacetic acids with alkenes for the simple and efficient preparation difluoromethylated thiochromanes 2,2-disubstituted-N-arylbutanamides derivatives has been developed. This approach includes good functional group tolerance, easily accessible starting materials, operational simplicity.

Язык: Английский

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Dehydroxylative Alkylation of α‐Hydroxy Carboxylic Acid Derivatives via a Spin‐Center Shift

Angewandte Chemie International Edition, Год журнала: 2022, Номер 61(25)

Опубликована: Апрель 7, 2022

Abstract A strategically distinct dehydroxylative alkylation reaction of α‐hydroxy carboxylic acid derivatives with alkenes is developed. The starts the attack a 4‐dimethylaminopyridine (DMAP)‐boryl radical to carbonyl oxygen atom, followed by spin‐center shift (SCS) trigger C−O bond scission. resulting α‐carbonyl radicals couple wide range furnish various alkylated products. This strategy allows for efficient conversion array amides and esters derived from several biomass molecules natural products value‐added compounds. Experimental computational studies verified mechanism.

Язык: Английский

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Generation of aryl radicals fromin situactivated homolytic scission: driving radical reactions by ball milling

Green Chemistry, Год журнала: 2022, Номер 24(11), С. 4557 - 4565

Опубликована: Янв. 1, 2022

The need for an operationally straightforward application of radical chemistry has led researchers to explore practical strategies obtain and trap radicals.

Язык: Английский

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Metal-free synthesis of difluoro/trifluoromethyl carbinol-containing chromones via tandem cyclization of o-hydroxyaryl enaminones

Organic & Biomolecular Chemistry, Год журнала: 2023, Номер 21(46), С. 9236 - 9241

Опубликована: Янв. 1, 2023

A convenient and efficient method for the synthesis of difluoro/trifluoromethyl carbinol-containing chromone derivatives has been developed.

Язык: Английский

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Water-bridged self-assembly of low-odor xanthate surfactant for selective flotation of chalcopyrite

Journal of Molecular Liquids, Год журнала: 2024, Номер 398, С. 124246 - 124246

Опубликована: Фев. 12, 2024

Язык: Английский

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