Chiral
transition
metal
oxide
nanoparticles
(CTMOs)
are
attracting
a
lot
of
attention
due
to
their
fascinating
properties.
Nevertheless,
elucidating
the
chirality
induction
mechanism
often
remains
major
challenge.
Herein,
synthesis
chiral
cobalt
mediated
by
histidine
(Co3
O4
@L-His
and
Co3
@D-His
for
synthesized
in
presence
L-
D-histidine,
respectively)
is
investigated.
Interestingly,
these
CTMOs
exhibit
remarkable
tunable
chiroptical
Their
analysis
x-ray
photoelectron,
Fourier
transform
infrared,
ultraviolet-visible
absorption
spectroscopy
indicates
that
ratio
Co2+
/Co3+
interactions
with
imidazole
groups
behind
In
addition,
use
development
sensitive,
rapid,
enantioselective
circular
dichroism-based
sensors
demonstrated,
allowing
direct
molecular
detection
discrimination
between
cysteine
or
penicillamine
enantiomers.
The
dichroism
response
exhibits
limit
enantiomers
as
low
10
µm.
Theoretical
calculations
suggest
ligand
exchange
coexistence
both
species
adsorbed
on
surface
responsible
enantiomeric
discrimination.
This
research
will
enrich
synthetic
approaches
obtain
enable
extension
applications
discovery
new
Light Science & Applications,
Год журнала:
2024,
Номер
13(1)
Опубликована: Авг. 1, 2024
Abstract
Chiral
assemblies
have
become
one
of
the
most
active
research
areas
due
to
their
versatility,
playing
an
increasingly
important
role
in
bio-detection,
imaging
and
therapy.
In
this
work,
chiral
UCNPs/Cu
x
OS@ZIF
nanoprobes
are
prepared
by
encapsulating
upconversion
nanoparticles
(UCNPs)
Cu
OS
(NPs)
into
zeolitic
imidazolate
framework-8
(ZIF-8).
The
novel
excited-state
energy
distribution-modulated
nanostructure
(NaYbF
4
@NaYF
:
Yb,
Er)
is
selected
as
fluorescence
source
donor
for
highly
efficient
resonance
transfer
(FRET).
NP
employed
acceptor
quench
luminescence
(UCL)
provide
circular
dichroism
(CD)
signal.
Utilizing
natural
adsorption
sorting
advantages
ZIF-8,
designed
nanoprobe
can
isolate
influence
other
common
disruptors,
thus
achieve
ultra-sensitive
selective
UCL/CD
dual-mode
quantification
H
2
S
aqueous
solution
living
cells.
Notably,
also
capable
vivo
intra-tumoral
tracking.
Our
work
highlights
multifunctional
properties
nanocomposites
sensing
opens
a
new
vision
idea
preparation
application
nanomaterials
biomedical
biological
analysis.
ACS Applied Nano Materials,
Год журнала:
2022,
Номер
5(10), С. 15102 - 15114
Опубликована: Окт. 10, 2022
Herein,
Co3O4
nanopolyhedrons
with
multi-mimics
of
peroxidase
(POD)-,
oxidase
(OXD)-,
catalase
(CAT)-,
and
glutathione
(GPx)-like
activities
were
developed
utilized
in
the
application
regulating
level
cellular
oxygen
hydrogen
peroxide
combined
polydopamine
(PDA).
It
was
found
that
multi-mimic
can
be
controlled
by
pH
OXD-
POD-like
best
when
4
but
became
weak
under
weakly
acidic
or
neutral
conditions.
Meanwhile,
CAT-like
activity
conditions,
GPx-like
better
conditions
than
According
to
high
especially
at
tumor
cell
microenvironment,
catalytically
transform
H2O2
into
O2
without
interferences
from
other
mimic
activities.
After
coating
PDA,
Co3O4@PDA
good
biocompatibility
dispersion
also
catalyzed
produce
microenvironment
efficiency.
The
corresponding
fluorescent
probes
used
monitor
process,
main
mechanisms
investigated
through
fluorescence
spectra
confocal
microscopy.
This
work
not
only
verifies
multi-enzyme
properties
provides
a
nanomaterial
for
regulation
content
cells
utilizing
enzyme
property
nanomaterial.
is
considered
concentration
variation
active
small
molecules
regulated
nanoenzymes
may
provide
some
basis
cancer
diagnosis
treatment.
Chemical Communications,
Год журнала:
2023,
Номер
59(87), С. 12959 - 12971
Опубликована: Янв. 1, 2023
The
article
provides
an
overview
of
recent
advances
in
chiral
nanomaterials
for
biosensing
applications,
including
individual
nanoparticles,
assemblies,
and
2D
film-based
sensors.
ACS Applied Nano Materials,
Год журнала:
2023,
Номер
6(5), С. 3357 - 3366
Опубликована: Март 1, 2023
Increasing
bacterial
resistance
has
led
to
the
aggravation
of
diseases
caused
by
microbial
infections,
posing
a
significant
threat
human
health.
The
multicascade
approach
is
more
efficient
than
single
treatment
for
resistant
bacteria.
Here,
we
describe
simple
method
fabricating
CoSe2
nanoparticles,
which
operate
as
single-component,
multienzyme-mimicking
nanoplatform
multiple
ROS
production.
simultaneously
exhibits
multienzymatic
activities
that
mimic
intrinsic
catalase,
peroxidase,
and
oxidase.
Furthermore,
under
synergistic
action
808
nm
NIR,
multienzyme
cascade
produced
photodynamics
play
stronger
role
against
drug-resistant
extended-spectrum
β-lactamase-producing
Escherichia
coli.
Therefore,
this
study
reveals
potential
nanoparticles
antimicrobial
reagents,
providing
promising
alternative
nanozyme
biomedical
use.
Chiral
transition
metal
oxide
nanoparticles
(CTMOs)
are
attracting
a
lot
of
attention
due
to
their
fascinating
properties.
Nevertheless,
elucidating
the
chirality
induction
mechanism
often
remains
major
challenge.
Herein,
synthesis
chiral
cobalt
mediated
by
histidine
(Co3
O4
@L-His
and
Co3
@D-His
for
synthesized
in
presence
L-
D-histidine,
respectively)
is
investigated.
Interestingly,
these
CTMOs
exhibit
remarkable
tunable
chiroptical
Their
analysis
x-ray
photoelectron,
Fourier
transform
infrared,
ultraviolet-visible
absorption
spectroscopy
indicates
that
ratio
Co2+
/Co3+
interactions
with
imidazole
groups
behind
In
addition,
use
development
sensitive,
rapid,
enantioselective
circular
dichroism-based
sensors
demonstrated,
allowing
direct
molecular
detection
discrimination
between
cysteine
or
penicillamine
enantiomers.
The
dichroism
response
exhibits
limit
enantiomers
as
low
10
µm.
Theoretical
calculations
suggest
ligand
exchange
coexistence
both
species
adsorbed
on
surface
responsible
enantiomeric
discrimination.
This
research
will
enrich
synthetic
approaches
obtain
enable
extension
applications
discovery
new
