Activating Metal–Organic Cages by Incorporating Functional M(ImPhen)₃ Metalloligands: From Structural Design to Applications

Accounts of Chemical Research, Год журнала: 2024, Номер 57(22), С. 3277 - 3291

Опубликована: Окт. 9, 2024

ConspectusThe emulation of ingenious biofunctions has been a research focus for several decades. Metal-organic cages (MOCs), as type discrete supramolecular assembly with well-defined shapes and cavities, have aroused great interest in chemists to imitate natural protein or enzymes. However, genuinely achieve tailored functionalities reactivities enzymes, the design cage structures combining both confined microenvironment active site is prerequisite. Therefore, integration functionalized motifs into MOCs expected provide feasible approach construct biofunctional nanospaces, which not only allows modulation properties applications such molecular recognition, transport, catalysis but also creates unique microenvironments that promote enzymatic effects special selectivities, thereby providing versatile platform exceptional biomimetic functions beyond.In this Account, we specifically on our toward engineering confined-nanospaces via incorporation M(ImPhen)

Язык: Английский

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The Applications of Metallacycles and Metallacages

Inorganics, Год журнала: 2023, Номер 11(2), С. 54 - 54

Опубликована: Янв. 22, 2023

Metallacycles and metallacages constitute a class of coordination compounds composed metal ions organic ligands. Because their precise stoichiometry, the flexibility viability design, metallacycles have attracted considerable attention as supramolecular assemblies. Various two-dimensional polygons, three-dimensional polyhedra, other nanoscale materials been constructed applied. The highly diverse structures, sizes, shapes endow with unique physical chemical properties make them suitable for various applications such encapsulation, separation, catalysis, biological science. Herein, we review recent developments in different fields. text highlights biomedical involving molecular recognition binding, antibacterial activity, especially cancer diagnosis treatment, including imaging, chemotherapy, PDT, PTT.

Язык: Английский

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Hierarchically Assembled Gigantic Fe/Co Cyanometallate Clusters Exhibiting Electron Transfer Behavior Above Room Temperature

Advanced Science, Год журнала: 2024, Номер 11(30)

Опубликована: Июнь 14, 2024

The construction of large and complex supramolecular architectures through self-assembly is at the forefront contemporary coordination chemistry. Notwithstanding great success in various systems using anionic bridges (e.g., O

Язык: Английский

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Tetraphenylethene-Based Molecular Cage with Coenzyme FAD: Conformationally Isomeric Complexation toward Photocatalysis-Assisted Photodynamic Therapy

Journal of the American Chemical Society, Год журнала: 2024, Номер 146(45), С. 30933 - 30946

Опубликована: Окт. 21, 2024

Flavin adenine dinucleotide (FAD), serving as a light-absorbing coenzyme factor, can undergo conformationally isomeric complexation within different enzymes to form various enzyme-coenzyme complexes, which exhibit photocatalytic functions that play crucial role in physiological processes. Constructing an artificial photofunctional system using FAD or its derivatives not only develop biocompatible systems with excellent activities but also further enhance our understanding of the biological systems. Here, we demonstrate supramolecular approach for constructing enzyme-coenzyme-type host-guest complex photoinduced catalytic function water. First, have designed and synthesized water-soluble tetraphenylethene (TPE)-based octacationic molecular cage (

Язык: Английский

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Aggregation-tuned the Förster resonance energy transfer signal between AIEE-active metallacycle and tetraphenylporphyrin

Tetrahedron Letters, Год журнала: 2025, Номер 156, С. 155456 - 155456

Опубликована: Янв. 9, 2025

Язык: Английский

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