Regrowth of gold nanoparticles facilitated utilizing small molecules ligand for high stability and performance

Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 161086 - 161086

Опубликована: Фев. 1, 2025

Язык: Английский

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Engineering Amphiphilic Gold Thiolate Clusters for Enhanced Luminescence and Controlled Assembly

Chemical Physics Impact, Год журнала: 2025, Номер unknown, С. 100877 - 100877

Опубликована: Апрель 1, 2025

Язык: Английский

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Photofunctional Gold Nanocluster Composites for Bioapplications

ACS Applied Bio Materials, Год журнала: 2024, Номер 7(5), С. 2695 - 2703

Опубликована: Май 3, 2024

Gold nanoclusters (AuNCs), with customized structures and diverse optical properties, are promising materials. Constructing composite systems by the assembly incorporation of AuNCs can utilize their properties to achieve diagnostic therapeutic applications in biological field. Therefore, exploration behaviors enhancement performance has attracted widespread interest. In this review, we introduce multiple interactions modes that prevalent nanocomposites microcomposites based on AuNCs. Then, functions AuNC composites for bioapplications demonstrated detail. These have inherited enhanced inherent performances meet requirements sensing treatments. Finally, discuss prospects highlight challenges opportunities biomedical applications.

Язык: Английский

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Tuning surface morphology of AuNPs film via thiourea as a stable SERS platform for methylene blue

Talanta, Год журнала: 2024, Номер 281, С. 126848 - 126848

Опубликована: Сен. 10, 2024

Язык: Английский

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Recyclable NiO/g-C3N4/ag hybrid substrates for sensitive SERS detection and photo-degradation of residual pesticides in beverages

Food Chemistry, Год журнала: 2024, Номер 464, С. 141935 - 141935

Опубликована: Ноя. 5, 2024

Язык: Английский

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Plasmonic Nanostars: Unique Properties That Distinguish Them from Spherical Nanoparticles from a Biosensing Perspective

Advanced Optical Materials, Год журнала: 2024, Номер 12(28)

Опубликована: Июль 31, 2024

Abstract Over the past three decades, plasmonic nanostructures, particularly spherical ones, have seen remarkable advancements. Recently, attention has shifted toward anisotropic nanoparticles, especially star‐shaped/branched structures such as nanostars (PNS), due to their distinct properties. PNS offers superior electromagnetic enhancement effects, larger surface areas, and well non‐linear unusual photothermal properties, setting them apart from counterparts. Despite significant progress in synthetic methods characterization of particles, challenges remain transitioning technology into practical use. In this perspective article, distinctive attributes biosensing applications are discussed, beginning with an exploration synthesis methodologies. Their optoelectronic properties examined discussed how these influence interaction different molecules a perspective. With focus on PNS, detailed insights offered unique current applications, future potential. By fostering discussion understanding development, article aims facilitate translation encouraging targeted improvements

Язык: Английский

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Fabrication of Raman reporter molecule–embedded magnetic SERS tag for ultrasensitive immunochromatographic monitoring of Cd ions and clenbuterol in complex samples

Colloids and Surfaces A Physicochemical and Engineering Aspects, Год журнала: 2024, Номер 702, С. 135159 - 135159

Опубликована: Авг. 23, 2024

Язык: Английский

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Label-Free Surface-Enhanced Raman Scattering for Genomic DNA Cytosine Methylation Reading

Molecules, Год журнала: 2025, Номер 30(2), С. 403 - 403

Опубликована: Янв. 18, 2025

DNA methylation has been widely studied with the goal of correlating genome profiles various diseases epigenetic mechanisms. Multiple approaches have developed that employ extensive steps, such as bisulfite treatments, polymerase chain reactions (PCR), restriction digestion, sequencing, mass analysis, etc., to identify methylation. In this article, we report a facile label-free surface-enhanced Raman scattering (SERS) spectroscopy system utilizes gold nanoparticles (AuNPs) for signal enhancement methylated DNA. The key innovation work is use anionic at high ionic strength introduce aggregation AuNPs When target present, presence methyl group in cytosine C5 position CpG sites induces peak 1350 cm−1. Our amplification-free limit detection (LOD) 5% and quantification (LOQ) 16% good specificity. method was applied determine hypermethylated levels germline colorectal cancer cell lines SW48 SW480. simple holds potential read disease-associated genomic

Язык: Английский

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Neural Network–Enhanced Electrochemical/SERS Dual-Mode Microfluidic Platform for Accurate Detection of Interleukin-6 in Diabetic Wound Exudates

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 22, 2025

Interleukin-6 (IL-6) plays a pivotal role in the inflammatory response of diabetic wounds, providing critical insights for clinicians development personalized treatment strategies. However, low concentration IL-6 biological samples, coupled with presence numerous interfering substances, poses significant challenge its rapid and accurate detection. Herein, we present dual-mode microfluidic platform integrating electrochemical (EC) surface-enhanced Raman spectroscopy (SERS) to achieve timely highly reliable quantification IL-6. Efficient binding between antibody-conjugated SERS nanoprobes is obtained through square-wave micromixer nonleaky obstacles, forming sandwich immunocomplexes capture antibodies on working electrode detection area, enabling acquisition both EC signals. This demonstrates excellent selectivity sensitivity, limits 0.085 0.047 pg/mL modes, respectively. Importantly, by incorporating neural network (NN) self-attention (SA) mechanism evaluate relative weights data from achieves quantitative accuracy up 99.8% across range 0.05–1000 pg/mL, demonstrating performance at concentrations. Moreover, NN-enhanced effectively detects wound exudates results that align closely clinical data. integrated offers promising potential cytokines.

Язык: Английский

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Ultrasensitive and multiplex SERS immunoassay for stroke subtype-specific biomarkers based on graphene oxide-supported nanofilms coated by roughened nanoboxes with extensive high-density hotspots

Biosensors and Bioelectronics, Год журнала: 2025, Номер 278, С. 117352 - 117352

Опубликована: Март 6, 2025

Язык: Английский

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