Multi-Aryl Pyrroles: Exploring Aggregation-Induced Emission for the Biological/Medical Applications
Dyes and Pigments,
Год журнала:
2025,
Номер
unknown, С. 112633 - 112633
Опубликована: Янв. 1, 2025
Язык: Английский
Molecular Fragmentation and Recombination for the Synthesis of GFP Chromophore Analogues
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
90(4), С. 1678 - 1682
Опубликована: Янв. 20, 2025
Green
fluorescent
protein
(GFP)
chromophores
are
widely
studied
as
moieties
for
sensing
and
imaging
applications.
Herein,
we
present
a
straightforward
synthetic
strategy
that
involves
the
reaction
of
glycine
amides
with
1,3-diketones
to
form
imidazolones
through
an
unusual
molecular
fragmentation
recombination
pathway.
Mechanistic
investigations,
including
crossover
experiments,
inspired
competing
incorporates
exogenous
ketones
into
products,
yielding
GFP
chromophore
analogues.
This
method
holds
potential
labeling
glycine-terminated
peptides.
Язык: Английский
Trendbericht: Organische Chemie 2025
Nachrichten aus der Chemie,
Год журнала:
2025,
Номер
73(3), С. 40 - 70
Опубликована: Фев. 28, 2025
Abstract
Highlights
von
November
2023
bis
2024:
die
erste
Einelektron‐C–C‐σ‐Bindung
und
Anti‐Bredt‐Verbindung;
gesättigte
Heterocyclen
elektrochemisch
funktionalisieren;
Ausrichten
diskotischer
Flüssigkristalle;
enantioselektive
Wagner‐Meerwein‐Umlagerung
reiner
Aliphaten;
photokatalytisch
Furanen
zu
Pyrrolen;
mit
Ammoniak
primären
Arylaminen;
Metallschrott
recyceln
ionischen
Flüssigkeiten;
terminale
Alkene
Ni‐Katalysatoren
zum
(Z)‐
oder
(E)‐Alken
isomerisieren;neue
Fungizide,
Medikamente
Alkaloide.