ACS Applied Bio Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 19, 2024
Afterglow
fluorescence
imaging
has
been
extensively
assessed
in
ultrasensitive
bioimaging.
Since
it
eliminates
the
need
for
real-time
excitation
light
and
thereby
circumvents
autofluorescence
background
of
tissue,
holds
tremendous
potential
accurate
biomedical
imaging.
However,
current
afterglow
probes
are
rare
emit
only
visible
to
near-infrared
(NIR)
range,
which
is
inadequate
vivo
To
resolve
this
issue,
an
ultrasound
(US)-activated
NIR-II
luminescence
probe
(NPs-Ce4-SN)
emitting
with
a
peak
at
∼1100
nm
was
developed.
This
nearly
400
red-shifted
compared
other
reported
probes.
Of
note,
after
US
termination,
NPs-Ce4-SN
undergoes
energy
transformation
produce
1O2
subsequently
internal
oxidation-reduction
reaction
afterglow,
generating
high
signal-to-noise
ratio
high-penetration
depth
In
vitro
experiments
revealed
that
good
biocompatibility
deep
tissue
penetration
depth,
suggesting
diagnostic
strategy
tumor
ratio.
Advanced Functional Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 21, 2025
Abstract
Tumor
cells
exploit
abnormal
redox
homeostasis
and
the
pro‐tumorigenic
effect
of
reactive
oxygen
species
(ROS)
to
enhance
their
survival
progression.
However,
excessively
high
levels
ROS
can
exceed
oxidative
stress
threshold
tumor
cells,
inducing
cell
death.
This
occur
by
selectively
elevating
concentration
H
2
O
in
through
both
endogenous
exogenous
mechanisms.
The
generated
serves
as
a
precursor
for
toxic
ROS,
such
•
OH
1
,
via
chemodynamic
photodynamic
therapy,
respectively,
leading
apoptosis,
necrosis,
ferroptosis.
Strategies
boost
include
direct
delivery
amplifying
generation
inhibiting
antioxidant
enzymes,
leveraging
glucose
oxidase,
employing
photocatalytic
therapy
(PCT),
utilizing
metal
peroxides.
Among
them,
peroxides
have
displayed
remarkable
performance
due
excellent
potential
elevate
within
while
simultaneously
normalizing
acidic
hypoxic
conditions
microenvironment
(TME).
Moreover,
these
nanostructures
sensitivity
complementary
treatments,
like
chemotherapy.
review
summarizes
advanced
perspectives
design,
synthesis,
comparative
analysis
‐generating
nanoplatforms,
emphasizing
capacity
treat
various
cancers.
Nature Communications,
Год журнала:
2025,
Номер
16(1)
Опубликована: Март 16, 2025
Abstract
Overall
artificial
photosynthesis,
as
a
promising
approach
for
sunlight-driven
CO
2
recycling,
requires
photocatalysts
with
efficient
light
adsorption
and
separate
active
sites
coupling
H
O
oxidation.
Here
we
show
In-based
metal–organic
framework
(MOF)
heterostructure,
i.e.,
In-porphyrin
(In-TCPP)
nanosheets
enveloping
an
In-NH
-MIL-68
(M68N)
core,
via
facile
one-pot
synthesis
that
utilises
competitive
nucleation
growth
of
two
organic
linkers
In
nodes.
The
coherent
interfaces
the
core@shell
MOFs
assure
structural
stability
which
will
function
heterojunctions
to
facilitate
transfer
photogenerated
charge
overall
photosynthesis.
In-TCPP
shell
in
heterostructure
improves
capabilities
visible
absorption
enhance
photocatalytic
reduction.
Simultaneously,
In-O
M68N
core
efficiently
catalyze
oxidation,
achieving
high
yields
HCOOH
(397.5
μmol
g
−1
h
)
(321.2
under
focused
sunlight
irradiation.
superior
performance
this
coupled
its
straightforward
synthesis,
shows
great
potential
mitigating
carbon
emissions
producing
valuable
chemicals
using
solar
energy.
Chemical Society Reviews,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 19, 2024
This
review
outlines
recent
advances
in
field-regulated
catalysis
and
reveals
the
key
role
of
dipole
manipulation
by
electric/magnetic/electromagnetic
fields.
ACS Applied Bio Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 11, 2024
Cancer
is
becoming
a
global
threat,
as
the
cancerous
cells
manipulate
themselves
frequently,
resulting
in
mutants
and
more
abnormalities.
Early-stage
real-time
detection
of
cancer
biomarkers
can
provide
insight
into
designing
cost-effective
diagnostic
therapeutic
modalities.
Nanoparticle
quantum
dot
(QD)-based
approaches
have
been
recognized
clinically
relevant
methods
to
detect
disease
at
molecular
level.
Over
decades,
an
emergent
noninvasive
approach,
photothermal
therapy
has
evolved
eradicate
cancer.
Moreover,
various
structures,
viz.,
nanoparticles,
clusters,
dots,
etc.,
tested
bioimaging
agents
identify
tumor
selectively.
Among
them,
QDs
versatile
probes.
They
attracted
enormous
attention
for
imaging
applications
due
their
unique
colloidal
stability,
optical
physicochemical
properties,
biocompatibility,
easy
surface
conjugation,
scalable
production,
etc.
However,
few
critical
concerns
QDs,
precise
engineering
sensing,
selective
interaction
with
biological
system,
associated
toxicity,
restrict
potential
intervention
curing
are
yet
be
explored.
According
U.S.
Food
Drug
Administration
(FDA),
there
no
specific
regulation
approval
nanomedicines.
Therefore,
these
nanomedicines
undergo
traditional
drug,
biological,
device
process.
market
survey
increasing,
prospects
translational
nanomedicine
very
promising.
From
this
perspective,
we
discuss
importance
imaging,
usage
pertinent
cancer,
especially
its
early
stages.
also
rapidly
growing
view
QDs.
The
long-term
safety
studies
cellular
could
enhance
visibility
bring
photothermally
active
clinical
stage
concurrently
FDA
approval.
ACS Applied Materials & Interfaces,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 11, 2024
The
field
of
photocatalysis
has
demonstrated
numerous
advantages
in
the
domains
environmental
protection,
energy,
and
materials
science.
However,
conventional
modification
methods
fail
to
simultaneously
enhance
carrier
separation
efficiency,
redox
capacity,
visible
light
absorption
solely
through
activation
due
intrinsic
band
structure
limitations
photocatalysts.
In
addition
methods,
introduction
an
external
field,
such
as
a
piezoelectric
can
effectively
address
deficiencies
each
step
photocatalytic
process
overall
performance.
assistance
overcomes
inherent
traditional
systems.
Hence,
this
review
provides
comprehensive
overview
recent
advancements
piezoelectric-assisted
thoroughly
investigates
interaction
between
alternating
processes.
Various
ideas
for
synergistic
enhancement
properties
are
also
explored.
This
multifield
catalytic
system
shows
remarkable
performance
stability,
pollutant
degradation,
energy
conversion,
distinguishing
it
from
single
Finally,
in-depth
analysis
is
conducted
challenges
prospects
associated
with
technology.
