Chemical Science,
Год журнала:
2019,
Номер
10(15), С. 4177 - 4184
Опубликована: Янв. 1, 2019
Palladium-catalyzed
dehydrogenative
B-H/C-H
cross
coupling
of
monocarborane
anions
with
alkenes
is
reported,
allowing
for
the
first
time
isolation
selectively
penta-alkenylated
boron
clusters.
The
reaction
cascade
regioselective
cage
positions,
leading
directly
to
B2-6
functionalization.
Under
mild
and
convenient
conditions,
styrenes,
benzylic
aliphatic
are
demonstrated
be
viable
partners
exclusive
vinyl-type
B-C
bond
formation.
Multiple
subsequent
transformations
provide
access
directing
group-free
products,
chiral
derivatives
penta-alkylated
cages.
five-fold
coupling,
combined
latter
reactions,
represents
a
powerful
methodology
straightforward
synthesis
new
classes
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 13, 2024
The
innovation
of
synthetic
strategies
for
selective
B-H
functionalization
is
a
pivotal
objective
in
the
realm
boron
cluster
chemistry.
However,
precise,
efficient,
and
rapid
bond
carboranes
that
distant
from
existing
functional
groups
remains
intractable
owing
to
limited
approaches
site-selective
control
established
methods.
Herein,
we
report
dative
bonding
activation
strategy
nonclassical
remote
site
Organic Process Research & Development,
Год журнала:
2024,
Номер
28(4), С. 949 - 977
Опубликована: Апрель 8, 2024
P-Chiral
phosphorus
ligands
received
little
attention
in
organic
chemistry
until
Knowles
made
his
landmark
contribution
asymmetric
hydrogenation
by
developing
the
P-chiral
CAMP
and
DIPAMP.
The
development
of
accelerated
end
last
century
with
advent
some
highly
efficient
renowned
for
hydrogenation,
including
BisP*,
TangPhos,
QuinoxP*,
DuanPhos,
et
al.
However,
most
reported
were
air-sensitive,
difficult
to
make,
or
lacked
structural
modularity,
hampering
their
availability
applicability.
sterically
electronically
tunable
is
particularly
desirable.
Over
past
decade,
a
family
hindered,
electron-rich,
structurally
tunable,
air-stable
dihydrobenzooxaphosphole
emerged
that
proved
be
versatile
various
transformations.
5
years
witnessed
an
increasing
number
studies
related
these
discovery
unprecedented
catalytic
properties
This
review
highlights
unique
catalysis
applications
synthesis
natural
products
therapeutic
agents.
Chemical Communications,
Год журнала:
2019,
Номер
55(20), С. 2892 - 2895
Опубликована: Янв. 1, 2019
The
synthesis
of
[1,1'-bis(o-carboranyl)]boranes
was
achieved
through
the
deprotonation
1,1'-bis(o-carborane)
reagents
followed
by
salt
metathesis
with
(iPr)2NBCl2.
X-ray
crystallography
confirms
planar
central
BC4
rings
and
Gutmann-Beckett
studies
reveal
an
increase
in
Lewis
acidity
at
boron
center
comparison
to
their
biphenyl
congener,
9-borafluorene.
Chemical Science,
Год журнала:
2019,
Номер
10(15), С. 4177 - 4184
Опубликована: Янв. 1, 2019
Palladium-catalyzed
dehydrogenative
B-H/C-H
cross
coupling
of
monocarborane
anions
with
alkenes
is
reported,
allowing
for
the
first
time
isolation
selectively
penta-alkenylated
boron
clusters.
The
reaction
cascade
regioselective
cage
positions,
leading
directly
to
B2-6
functionalization.
Under
mild
and
convenient
conditions,
styrenes,
benzylic
aliphatic
are
demonstrated
be
viable
partners
exclusive
vinyl-type
B-C
bond
formation.
Multiple
subsequent
transformations
provide
access
directing
group-free
products,
chiral
derivatives
penta-alkylated
cages.
five-fold
coupling,
combined
latter
reactions,
represents
a
powerful
methodology
straightforward
synthesis
new
classes
