RSC Sustainability, Год журнала: 2024, Номер 2(7), С. 1963 - 1968
Опубликована: Янв. 1, 2024
A halogen-free bleaching of shellac was developed using electrochemically generated peroxodicarbonate with acetonitrile as an activator. reduced damage is obtained compared to previous reports.
Язык: Английский
Organic Letters, Год журнала: 2023, Номер 25(12), С. 2134 - 2138
Опубликована: Март 20, 2023
Sulfilimines are valuable compounds both in organic synthesis and pharmaceuticals. Here we developed a mild simplified method for preparation of sulfilimines via selective S–C bond formation rather than traditional S–N formation. The is attractive useful the following reasons: it uses readily available alkylation reagent such alkyl bromide or iodide, water as solvent, easy to perform, convenient late-stage diversification drugs.
Язык: Английский
Процитировано
45
Nature, Год журнала: 2025, Номер 637(8045), С. 354 - 361
Опубликована: Янв. 8, 2025
Язык: Английский
Процитировано
3
ChemElectroChem, Год журнала: 2024, Номер 11(8)
Опубликована: Янв. 18, 2024
Abstract Synthetic electro‐organic chemistry is advancing to a well‐established methodology in academic research and industry. The simple process control minimizes reagent waste avoids using toxic environmentally unfriendly redox agents, providing feasible sustainable alternative conventional techniques. However, fundamental disadvantage, the necessity of ion‐conductive components within electrolyte. recovery these supporting electrolytes, as well product isolation, pose challenges for work‐up strategies. This review presents following electrochemical protocols featuring material‐ resource‐saving strategy: dual role electrolytes conductivity enabling reagents or meditators. first conclude categorize strategies electrolytes. It may inspire electrochemists advance development optimization synthesis towards more resource‐efficient reaction control.
Язык: Английский
Процитировано
17
Green Chemistry, Год журнала: 2024, Номер 26(10), С. 5862 - 5868
Опубликована: Янв. 1, 2024
Peroxodicarbonate, a sustainable electrochemically generated oxidizer, provides the means to transform abundant hydroxybenzaldehydes into valuable phenols in safe and effective manner.
Язык: Английский
Процитировано
7
Chemie Ingenieur Technik, Год журнала: 2025, Номер unknown
Опубликована: Март 18, 2025
Abstract Organic electrosynthesis is a potential enabler for the energy and resource transition in chemical industry as it offers sustainable alternative to homogeneous or heterogeneous processes producing fine commodity chemicals. It utilizes electricity instead of hazardous reagents and, thus, also allows reducing product's carbon footprint waste production. enables dynamic operation safe due galvanostatic process control. Electro‐organic are not yet widespread. Engineering tools have been tailored electro‐organic processes, more quantitative model‐based insight needed. Extensive adoption requires efforts regarding electrode material performance stability, scalable reactor design, digitization. Addressing these issues interdisciplinary collaboration, particularly between chemists engineers, accelerate implementation with high efficiency economic feasibility.
Язык: Английский
Процитировано
1
JACS Au, Год журнала: 2025, Номер 5(5), С. 2359 - 2367
Опубликована: Апрель 29, 2025
The invention of versatile linkage agents provides the chemical basis for SuFEx chemistry. Sulfonimidoyl fluorides and sulfondiimidoyl are aza-isosteres sulfonyl with diverse reactivity through fine-tuning N-substituents. However, limited synthetic approaches impede their wide applications in Herein, we develop a straightforward electrochemical strategy sulfonimidoyl- sequential oxidations readily available sulfenamides via sulfinamide iminosulfinamide intermediates, respectively. previously rarely investigated (bis)-sulfondiimidoyl now easily accessible participate chemistry oxygen nitrogen nucleophiles, macrocyclization, polymerization.
Язык: Английский
Процитировано
1
Angewandte Chemie International Edition, Год журнала: 2024, Номер 63(35)
Опубликована: Май 15, 2024
Sulfinamidines are promising aza-S
Язык: Английский
Процитировано
6
Green Chemistry, Год журнала: 2023, Номер 25(22), С. 9092 - 9096
Опубликована: Янв. 1, 2023
An efficient iron-catalyzed sulfur alkylation of sulfenamides with diazo compounds for the synthesis functionalized sulfilimines is developed under air conditions.
Язык: Английский
Процитировано
12
The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(23), С. 16116 - 16121
Опубликована: Ноя. 20, 2023
Herein, we present a copper-catalyzed oxidative amination of sulfenamides for the synthesis sulfinamidines. By employment air as terminal oxidant, diverse array secondary and primary amines can be efficiently transformed into their corresponding products. This method is well-suited last-stage functionalization, underlying mechanism has been investigated. The transformation characterized by exceptional chemoselectivity, mild conditions, facile operation, broad substrate compatibility, which have significant implications fields pharmaceuticals organic synthesis.
Язык: Английский
Процитировано
12
Cell Reports Physical Science, Год журнала: 2024, Номер 5(5), С. 101927 - 101927
Опубликована: Апрель 15, 2024
4H-4-Hydroxybenzo[e]-1,2,4-thiadiazine-1,1-dioxides are based on a widely found structural motif for pharmaceutical applications, having an additional unique exocyclic N–O bond that is not accessible by conventional synthetic routes. Electrochemistry offers sustainable tool the direct synthesis of these heterocyclic structures containing this N-hydroxy modification. Here, we report highly selective 4H-4-hydroxybenzo[e]-1,2,4-thiadiazine-1,1-dioxides reduction available nitro arenes in almost quantitative yields. The electro-synthetic protocol applied to more than 40 diverse examples, highlighting versatility method. Furthermore, technical relevance demonstrated two multi-gram-scale syntheses.
Язык: Английский
Процитировано
5