Circadian Typology: A Comprehensive Review

Chronobiology International, Год журнала: 2012, Номер 29(9), С. 1153 - 1175

Опубликована: Сен. 24, 2012

The interest in the systematic study of circadian typology (CT) is relatively recent and has developed rapidly two last decades.All existing data suggest that this individual difference affects our biological psychological functioning, not only health, but also disease.In present study, we review current literature concerning psychometric properties validity CT measures as well individual, environmental genetic factors influence CT.We a brief overview markers are used to define differences between groups (sleep-wake cycle, body temperature, cortisol, melatonin), assess implications for adjustment shift work jet-lag.We terms cognitive abilities, personality traits incidence psychiatric disorders.When necessary, have emphasized methodological limitations exist today suggested some future avenues order overcome these.This new field professionals many different areas (research, labor, academic, clinical) provides state art discussion allow integrate chronobiological aspects human behavior into their daily practice.

Язык: Английский

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Molecular Components of the Mammalian Circadian Clock

Handbook of experimental pharmacology, Год журнала: 2013, Номер unknown, С. 3 - 27

Опубликована: Янв. 1, 2013

Язык: Английский

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Circadian Rhythms and Sleep in Drosophila melanogaster

Genetics, Год журнала: 2017, Номер 205(4), С. 1373 - 1397

Опубликована: Март 30, 2017

The advantages of the model organism Drosophila melanogaster, including low genetic redundancy, functional simplicity, and ability to conduct large-scale screens, have been essential for understanding molecular nature circadian (∼24 hr) rhythms, continue be valuable in discovering novel regulators rhythms sleep. In this review, we discuss current these interrelated biological processes wider implications research. Clock genes period timeless were first discovered screens developed 1970s. Feedback on their own transcription forms core clock, accurately timed expression, localization, post-transcriptional modification, function is thought critical maintaining cycle. Regulators, several phosphatases kinases, act different steps feedback loop ensure strong rhythms. Approximately 150 neurons fly brain that contain components clock together translate intracellular cycling into rhythmic behavior. We how groups serve functions allowing clocks entrain environmental cues, driving behavioral outputs at times day, flexible responses conditions. neuropeptide PDF provides an important signal synchronize neurons, although details accomplishes are still being explored. Secreted signals from also influence other tissues. SLEEP is, part, regulated by which ensures appropriate timing sleep, but amount quality sleep determined mechanisms a homeostatic balance between wake. Flies useful identifying large set genes, molecules, neuroanatomic loci regulating amount. Conserved aspects regulation flies mammals include wake-promoting roles catecholamine neurotransmitters involvement hypothalamus-like regions, regions implicated less clear parallels. Sleep subject factors such as food availability, stress, social environment. beginning understand identified molecules interact with each other, environment, regulate researchers can take advantage increasing mechanistic behaviors, learning memory, courtship, aggression, loss impacts behaviors. thus remain tool both discovery deep

Язык: Английский

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Chronobiology by moonlight

Proceedings of the Royal Society B Biological Sciences, Год журнала: 2013, Номер 280(1765), С. 20123088 - 20123088

Опубликована: Июль 3, 2013

Most studies in chronobiology focus on solar cycles (daily and annual). Moonlight the lunar cycle received considerably less attention by chronobiologists. An exception are rhythms intertidal species. Terrestrial ecologists long ago acknowledged effects of moonlight predation success, consequently risk, foraging behaviour habitat use, while marine biologists have focused more mainly reproduction synchronization with relation to Moon phase. Lately, several different animal taxa addressed role determining activity studied underlying mechanisms. In this paper, we review ecological behavioural evidence showing effect activity, discuss adaptive value these changes, describe possible mechanisms effect. We will also refer other sources night-time light ('light pollution') highlight open questions that demand further studies.

Язык: Английский

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Two sides of a coin: ecological and chronobiological perspectives of timing in the wild

Philosophical Transactions of the Royal Society B Biological Sciences, Год журнала: 2017, Номер 372(1734), С. 20160246 - 20160246

Опубликована: Окт. 9, 2017

Most processes within organisms, and most interactions between organisms their environment, have distinct time profiles. The temporal coordination of such is crucial across levels biological organization, but disciplines differ widely in approaches to study timing. Such differences are accentuated ecologists, who centrally concerned with a holistic view an organism relation its external chronobiologists, emphasize internal timekeeping the mechanisms adjustment environment. We argue that ecological chronobiological perspectives complementary, studies at intersection will enable both fields jointly overcome obstacles currently hinder progress. However, achieve this integration, we first cross some conceptual barriers, clarifying prohibitively inaccessible terminologies. critically assess main assumptions concepts either field, as well common interests. Both intersect need understand extent regulation plasticity, concept 'chronotype', i.e. characteristic properties individuals which targets natural sexual selection. then highlight promising developments, point out open questions, acknowledge difficulties propose directions for further integration through Wild Clock research.This article part themed issue 'Wild Clocks: integrating chronobiology ecology free-living animals'.

Язык: Английский

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Capturing continuous, long timescale behavioral changes in Drosophila melanogaster postural data

PLoS Computational Biology, Год журнала: 2025, Номер 21(2), С. e1012753 - e1012753

Опубликована: Фев. 3, 2025

Animal behavior spans many timescales, from short, seconds-scale actions to daily rhythms over hours life-long changes during aging. To access longer timescales of behavior, we continuously recorded individual Drosophila melanogaster at 100 frames per second for up 7 days a time in featureless arenas on sucrose-agarose media. We use the deep learning framework SLEAP produce full-body postural dataset 47 individuals resulting nearly 2 billion pose instances. identify stereotyped behaviors such as grooming, proboscis extension, and locomotion ethograms explore how flies' varies across day experiment. find distinct patterns all behaviors, adding specific information about trends different grooming modalities, extension duration, speed what is known D. circadian cycle. Using our holistic measurements that hour after dawn unique point pattern behavioral composition this tracks well with other indicators health fraction spend moving vs. resting. The method, data, analysis presented here give us new clearer picture revealing novel features hint unexplored underlying biological mechanisms.

Язык: Английский

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Light and the Human Circadian Clock

Handbook of experimental pharmacology, Год журнала: 2013, Номер unknown, С. 311 - 331

Опубликована: Янв. 1, 2013

Язык: Английский

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Molecular basis of flowering under natural long-day conditions in Arabidopsis

Nature Plants, Год журнала: 2018, Номер 4(10), С. 824 - 835

Опубликована: Сен. 11, 2018

Язык: Английский

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Circadian and Circalunar Clock Interactions in a Marine Annelid

Cell Reports, Год журнала: 2013, Номер 5(1), С. 99 - 113

Опубликована: Сен. 26, 2013

Язык: Английский

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Time‐restricted feeding for prevention and treatment of cardiometabolic disorders

The Journal of Physiology, Год журнала: 2017, Номер 595(12), С. 3691 - 3700

Опубликована: Март 10, 2017

The soaring prevalence of obesity and diabetes is associated with an increase in comorbidities, including elevated risk for cardiovascular diseases (CVDs). CVDs continue to be among the leading causes death disability United States. While increased nutritional intake from energy-dense diet known disrupt metabolic homeostasis contributes disease risk, circadian rhythm disruption emerging as a new factor CVD. Circadian rhythms coordinate health via temporal control organismal metabolism physiology. Thus, interventions that improve are prospective entry points mitigate cardiometabolic risk. Although light strong modulator neural clock, time food dominant agent affects clocks organs. We discovered imposing time-restricted feeding (TRF) regimen which all caloric intakes occur consistently within ≤ 12 h every day exerts many benefits. TRF prevents excessive body weight gain, improves sleep, attenuates age- diet-induced deterioration cardiac performance. Using integrative approach combines Drosophila melanogaster (fruit fly) genetics transcriptome analyses it was found beneficial effects mediated by ATP-dependent TCP/TRiC/CCT chaperonin mitochondrial electron transport chain components. Parallel studies rodents have shown reduces risks maintaining homeostasis. As modern humans live under extended periods wakefulness ingestion events, daily eating pattern offers potential target lifestyle intervention reduce CVD

Язык: Английский

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