The
development
of
antimicrobial
drug
resistance
among
pathogenic
bacteria
and
fungi
is
one
the
most
significant
health
issues
21st
century.
Recently,
advances
in
nanotechnology
have
led
to
nanomaterials,
particularly
metals
that
exhibit
properties.
These
metal
nanomaterials
emerged
as
promising
alternatives
traditional
therapies.
In
this
review,
a
broad
overview
their
synthesis,
properties,
interactions
with
micro-organisms
first
provided.
Secondly,
range
demonstrate
passive
properties
are
outlined
in-depth
analysis
comparison
stimuli-responsive
provided,
which
represent
next
generation
microbiocidal
nanomaterials.
stimulus
applied
activate
such
includes
light
(including
photocatalytic
photothermal)
magnetic
fields,
can
induce
hyperthermia
kinetically
driven
activation.
Broadly,
review
aims
summarize
currently
available
research
provide
future
scope
for
nanomaterial-based
technologies,
those
be
activated
through
externally
stimuli.
Trends in Microbiology,
Год журнала:
2020,
Номер
28(8), С. 668 - 681
Опубликована: Апрель 21, 2020
The
'matrixome'
is
the
inventory
of
currently
known
biomolecules
(polysaccharides,
nucleic
acids,
proteins,
lipids,
and
lipoproteins)
their
molecular,
structural,
functional
diversity
associated
with
biofilm
assembly,
its
physicochemical
virulence
attributes.The
structural
biochemical
properties
matrixome
provide
emergent
biofilms,
including
surface
adhesion,
spatial
chemical
heterogeneities,
synergistic/competitive
polymicrobial
interactions,
antimicrobial
recalcitrance,
virulence.Combinatorial
treatment
strategies
are
crucial
to
eradicate
biofilms
by
targeting
functionally
structurally
complex
extracellular
polymeric
matrix
embedded
microbial
cells.Due
limited
knowledge
EPS
there
an
urgent
need
for
more
experimental
in
vivo
mechanistic
studies.
Biofilms
consist
communities
a
3D
matrix.
composed
array
substances
(EPS)
that
contribute
unique
attributes
lifestyle
virulence.
This
ensemble
chemically
diverse
termed
'matrixome'.
composition
mechanisms
formation,
role
biology,
function,
microenvironment
being
revealed.
perspective
article
highlights
recent
advances
about
multifaceted
development,
physical–chemical
properties,
biofilms.
We
emphasize
biofilm-specific
conditions
such
as
could
lead
precise
effective
antibiofilm
approaches.
also
discuss
context
in-depth
analyses
mixed
many
human
infectious
diseases.
Chemical Society Reviews,
Год журнала:
2019,
Номер
48(2), С. 428 - 446
Опубликована: Янв. 1, 2019
Bacterial-infections
are
mostly
due
to
bacteria
in
their
biofilm-mode
of
growth.
Nanotechnology-based
antimicrobials
possess
excellent
potential
biofilm-infection
control,
overcoming
the
biological
barriers
biofilms.
Advanced Functional Materials,
Год журнала:
2020,
Номер
30(22)
Опубликована: Март 17, 2020
Abstract
Microbial
colonization
on
material
surfaces
is
ubiquitous.
Biofilms
derived
from
surface‐colonized
microbes
pose
serious
problems
to
the
society
both
an
economical
perspective
and
a
health
concern.
Incorporation
of
antimicrobial
nanocompounds
within
or
surface
materials,
by
coatings,
prevent
microbial
adhesion
kill
microorganisms
after
their
attachment
biofilms,
represents
important
strategy
in
increasingly
challenging
field.
Over
last
decade,
many
studies
have
been
devoted
preparing
meta‐based
nanomaterials
that
possess
antibacterial,
antiviral,
antifungal
activities
combat
pathogen‐related
diseases.
Herein,
overview
state‐of‐the‐art
nanosized
metal‐based
compounds
provided,
including
metal
oxide
nanoparticles
as
well
transition
nanosheets.
The
mechanism
these
nanostructures
biomedical
applications
such
catheters,
implants,
medical
delivery
systems,
tissue
engineering,
dentistry
are
discussed.
Their
properties
potential
caveats
cytotoxicity,
diminishing
efficacy,
induction
resistance
materials
incorporating
reviewed
provide
backdrop
for
future
research.
Microbiology and Molecular Biology Reviews,
Год журнала:
2020,
Номер
84(3)
Опубликована: Авг. 11, 2020
In
many
natural
and
clinical
settings,
bacteria
are
associated
with
some
type
of
biotic
or
abiotic
surface
that
enables
them
to
form
biofilms,
a
multicellular
lifestyle
embedded
in
an
extracellular
matrix.
Journal of Physics D Applied Physics,
Год журнала:
2020,
Номер
53(30), С. 303001 - 303001
Опубликована: Март 20, 2020
Novel
plasma-based
technologies
that
offer
maximum
efficiency
at
minimal
environmental
costs
are
expected
to
further
promote
the
sustainable
societal
and
economic
development.
Unique
transfer
of
chemical
reactivity
energy
from
gaseous
plasmas
water
takes
place
in
absence
any
other
chemicals,
but
results
a
product
with
notable
transient
broad-spectrum
biological
activity,
referred
as
plasma-activated
(PAW).
These
features
make
PAW
green
prospective
solution
for
wide
range
biotechnology
applications,
purification
biomedicine.
Here,
we
present
succinct
review
how
novel,
efficient
methods
based
on
non-equilibrium
reactive
plasma
chemistries
can
be
applied
low-cost
natural
sources
produce
applications
while
same
time
minimising
process
steps
dramatically
reducing
use
expensive
and/or
hazardous
reagents.
Despite
recent
exciting
developments
this
field,
there
presently
is
no
topical
which
specifically
focuses
underlying
physics
chemistry
related
water.
We
focus
generation,
origin
species
PAW,
its
analytical
potentially
different
mechanisms
regulate
bio-activities
biotech-applications
their
roles
determining
efficacy
selectivity.
then
advances
our
understanding
plasma-water
interactions,
briefly
outlining
current
proposed
agriculture,
food
Finally,
outline
future
research
directions
challenges
may
hinder
translation
these
into
real-life
applications.
Overall,
will
provide
much
needed
insights
fundamental
aspects
required
optimization
biochemical
activity
environment-
human-health-friendly,
energy-efficient
strategy
real
life
Frontiers in Chemistry,
Год журнала:
2021,
Номер
9
Опубликована: Июль 13, 2021
Diverse
applications
of
nanoparticles
(NPs)
have
revolutionized
various
sectors
in
society.
In
the
recent
decade,
particularly
magnetic
(MNPs)
gained
enormous
interest
owing
to
their
specialized
areas
such
as
medicine,
cancer
theranostics,
biosensing,
catalysis,
agriculture,
and
environment.
Controlled
surface
engineering
for
design
multi-functional
MNPs
is
vital
achieving
desired
application.
The
demonstrated
great
efficacy
thermoelectric
materials,
imaging
agents,
drug
delivery
vehicles,
biosensors.
present
review,
first
we
briefly
discussed
main
synthetic
methods
MNPs,
followed
by
characterizations
composition.
Then
potential
different
with
representative
examples.
At
end,
gave
an
overview
on
current
challenges
future
prospects
MNPs.
This
comprehensive
review
not
only
provides
mechanistic
insight
into
synthesis,
functionalization,
application
but
also
outlines
limits
prospects.
Materials,
Год журнала:
2020,
Номер
13(14), С. 3224 - 3224
Опубликована: Июль 20, 2020
As
a
phenolic
acid,
tannic
acid
can
be
classified
into
polyphenolic
group.
It
has
been
widely
studied
in
the
biomedical
field
of
science
because
it
presents
unique
antiviral
as
well
antibacterial
properties.
Tannic
reported
to
present
activity
against
Influeneza
A
virus,
Papilloma
viruses,
noroviruses,
Herpes
simplex
virus
type
1
and
2,
human
immunodeficiency
(HIV)
both
Gram-positive
Gram-negative
bacteria
