Nature Reviews Microbiology, Год журнала: 2019, Номер 17(5), С. 284 - 294
Опубликована: Март 28, 2019
Язык: Английский
Microbiome, Год журнала: 2017, Номер 5(1)
Опубликована: Янв. 31, 2017
Symbiotic bacteria affect insect physiology and ecology. They may also mediate insecticide resistance within their hosts thereby impact pest vector control practices. Here, we document a novel mechanism of in which gut symbiont the tephritid fruit fly Bactrocera dorsalis enhances to organophosphate trichlorphon.We demonstrated that Citrobacter sp. (CF-BD) plays key role degradation trichlorphon. Based on comparative genomics analysis with other species, phosphatase hydrolase genes were identified CF-BD. These CF-BD had higher expression when trichlorphon was present. inoculated isolated obtained resistance, while antibiotic-treated flies less resistant confirming resistance.Our findings suggest symbiont-mediated can readily develop B. represent more widely relevant than previously recognized.
Язык: Английский
Процитировано
346
mBio, Год журнала: 2016, Номер 7(2)
Опубликована: Апрель 22, 2016
A paradigm shift has recently transformed the field of biological science; molecular advances have revealed how fundamentally important microorganisms are to many aspects a host's phenotype and evolution. In process, an era "holobiont" research emerged investigate intricate network interactions between host its symbiotic microbial consortia. Marine sponges early-diverging metazoa known for hosting dense, specific, often highly diverse communities. Here we synthesize current thoughts about environmental evolutionary forces that influence diversity, specificity, distribution symbionts within sponge holobiont, explore physiological pathways contribute holobiont function, describe mechanisms underpin establishment maintenance these partnerships. The collective genomes form hologenome, highlight define sponge's in fact act on genomic interplay different components holobiont.
Язык: Английский
Процитировано
300
PLoS Genetics, Год журнала: 2011, Номер 7(2), С. e1001314 - e1001314
Опубликована: Фев. 17, 2011
Recent research has provided mechanistic insight into the important contributions of gut microbiota to vertebrate biology, but questions remain about evolutionary processes that have shaped this symbiosis. In present study, we showed in experiments with gnotobiotic mice evolution Lactobacillus reuteri rodents resulted emergence host specialization. To identify genomic events marking adaptations murine host, compared genome rodent isolate L. 100-23 human F275, and identified hundreds genes were specific each strain. order differentiate true host-specific content from strain-level differences, comparative hybridizations performed query 57 strains originating six different hosts combination sequence comparisons nine encompassing five phylogenetic lineages species. This approach revealed strains, although showing a high degree plasticity, possessed inventory was rare or absent other hosts. The distinct reflected niche characteristics gastrointestinal tracts their respective hosts, inactivation seven out eight representative rodent-specific impaired ecological performance mice. analyses suggested fundamentally trends populations, former possessing large adaptable pan-genome while latter being subjected process reductive evolution. conclusion, study experimental evidence molecular basis for specificity symbiont, it process.
Язык: Английский
Процитировано
287
Annual Review of Ecology Evolution and Systematics, Год журнала: 2013, Номер 44(1), С. 623 - 643
Опубликована: Сен. 20, 2013
Vertical and horizontal transmission are terms that describe the transfer of symbionts from parents to offspring among unrelated hosts, respectively. Many symbionts, including parasites, pathogens, mutualists, microbiota, use a combination both strategies, known as mixed-mode (MMT). Here I review what is about evolution, ecology, epidemiology with MMT compare our expectations for single-mode strategies. Symbionts common and, in comparison show many surprising features. combines best two worlds regard ecological conditions required persistence plays role evolution virulence genome architecture. Even rare by minority type these modes can make big difference system. This explores conceptual issues surrounding dynamics reviewing literature entire range host symbiont taxa.
Язык: Английский
Процитировано
267
Nature Communications, Год журнала: 2017, Номер 8(1)
Опубликована: Июль 4, 2017
Organisms across the tree of life form symbiotic partnerships with microbes for metabolism, protection and resources. While some hosts evolve extreme dependence on their symbionts, others maintain facultative associations. Explaining this variation is fundamental to understanding when symbiosis can lead new higher-level individuals, such as during evolution eukaryotic cell. Here we perform phylogenetic comparative analyses 106 unique host-bacterial symbioses test correlations between symbiont function, transmission mode, genome size host dependence. We find that both mode function are correlated dependence, reductions in fitness being greatest nutrient-provisioning, vertically transmitted symbionts removed. also a negative correlation vertically, but not horizontally, symbionts. These results suggest population structure important driving irreversible
Язык: Английский
Процитировано
265
Nature Reviews Microbiology, Год журнала: 2019, Номер 17(5), С. 271 - 283
Опубликована: Март 13, 2019
Язык: Английский
Процитировано
265
Pediatric Obesity, Год журнала: 2017, Номер 12(S1), С. 3 - 17
Опубликована: Апрель 26, 2017
Summary The colonization of the gut with microbes in early life is critical to developing newborn immune system, metabolic function and potentially future health. Maternal are transmitted offspring during childbirth, representing a key step infant gut. Studies meconium suggest that bacteria present foetal prior birth, meaning could occur prenatally. Animal studies have shown prenatal transmission foetus possible, physiological changes observed pregnant mothers indicate utero transfer likely humans as well. However, direct evidence lacking. Understanding timing mechanisms involved first human comprehensive understanding microbiome. This review will discuss supporting from mother infants. We also sources transferred bacteria, modifiers maternal microbiomes their potential role Well‐designed longitudinal birth account for established microbiome challenging, but be necessary confirm further our knowledge
Язык: Английский
Процитировано
258
Current Opinion in Microbiology, Год журнала: 2016, Номер 35, С. 23 - 29
Опубликована: Ноя. 28, 2016
Язык: Английский
Процитировано
255
The ISME Journal, Год журнала: 2010, Номер 5(3), С. 446 - 460
Опубликована: Сен. 30, 2010
Язык: Английский
Процитировано
254
Proceedings of the National Academy of Sciences, Год журнала: 2012, Номер 109(20)
Опубликована: Апрель 19, 2012
Many insects are associated with obligate symbiotic bacteria, which localized in specialized cells called bacteriocytes, vertically transmitted through host generations via ovarial passage, and essential for growth reproduction of their hosts. Although vertical transmission is pivotal maintenance such intimate host-symbiont associations, molecular cellular mechanisms underlying the process largely unknown. Here we report a mechanism symbiont Buchnera pea aphid Acyrthosiphon pisum. In body, from maternal bacteriocytes to adjacent blastulae at ovariole tips highly coordinated manner. By making use symbiont-manipulated strains A. pisum, demonstrated that facultative Serratia is, unlike Buchnera, not blastulae, suggesting specific transmission. EM observations revealed series exo-/endocytotic processes operating bacteriocyte-blastula interface: exocytosed bacteriocyte, temporarily released extracellular space, endocytosed by posterior syncytial cytoplasm blastula. These results suggest selective likely attributable Buchnera-specific exocytosis whereas both nonselectively incorporated endocytotic activity region The sophisticated must have evolved ensure association, symbionts like may coopt component entry into embryos.
Язык: Английский
Процитировано
249