Consensus Parameter: Research Methodologies to Evaluate Neurodevelopmental Effects of Pubertal Suppression in Transgender Youth DOI Creative Commons
Diane Chen, John F. Strang, Victoria D. Kolbuck

и другие.

Transgender Health, Год журнала: 2020, Номер 5(4), С. 246 - 257

Опубликована: Июнь 9, 2020

Purpose: Pubertal suppression is standard of care for early pubertal transgender youth to prevent the development undesired and distressing secondary sex characteristics incongruent with gender identity. Preliminary evidence suggests improves mental health functioning. Given widespread changes in brain cognition that occur during puberty, a critical question whether this treatment impacts neurodevelopment. Methods: A Delphi consensus procedure engaged 24 international experts neurodevelopment, development, puberty/adolescence, neuroendocrinology, statistics/psychometrics identify priority research methodologies address empirical question: associated real-world neurocognitive sequelae? Recommended study approaches reaching 80% were included parameter. Results: The identified 160 initial expert recommendations, 44 which ultimately achieved consensus. Consensus design elements include following: minimum three measurement time points, staging at baseline, statistical modeling analyses, use analytic account heterogeneity, multiple comparison groups minimize limitations any one group. untreated matched on stage, cisgender (i.e., congruent) an independent sample from large-scale database. domains assessment includes: health, executive function/cognitive control, social awareness/functioning. Conclusion: An interdisciplinary team around primary methods assessing neurodevelopmental effects benefits and/or difficulties) youth.

Язык: Английский

Identifying organizations’ dynamic capabilities for sustainable digital transformation: A mixed methods study DOI
A. Karim Feroz, Hangjung Zo, Jiyong Eom

и другие.

Technology in Society, Год журнала: 2023, Номер 73, С. 102257 - 102257

Опубликована: Апрель 27, 2023

Язык: Английский

Процитировано

21

Ultra-processed food advertisements dominate the food advertising landscape in two Stockholm areas with low vs high socioeconomic status. Is it time for regulatory action? DOI Creative Commons
Petter Fagerberg, Billy Langlet,

Aleksandra Oravsky

и другие.

BMC Public Health, Год журнала: 2019, Номер 19(1)

Опубликована: Дек. 1, 2019

Abstract Background Ultra-processed food consumption is a risk factor for obesity and has negative environmental impact. Food companies spend billions of dollars on advertisements each year to increase the ultra-processed food. In Australia, USA, New Zealand, most around schools in train stations promote food, but no similar studies have been conducted Sweden. The aim this study was explore proportion two districts Stockholm, Sweden with low vs. high socioeconomic status (SES). Methods Two independent researchers (per area) mapped all advertisements, including storefronts, Stockholm districts. During consecutive days, were photographed Skärholmen (low SES district), Östermalmstorg (high streets inside outside subway stations, as well local shopping malls. Advertisements promoting products identified trained dietician categorized whether they promoted foods. Chi-Square test differences between areas. Results total, 4092 ( n = 1935) Östermalm 2157). 32.8% while 65.4% A significantly higher out total area, irrespective researcher taking pictures (74.6% 61.8%, p < 0.001 70.4% 54.8%, 0.001). There significant difference Conclusions This provides initial evidence about scale exposure across areas Stockholm. observed concerning sharp contrast Swedish dietary guidelines that recommend reduced such Based our results, residents might be more exposed than those If findings are confirmed additional areas, should considered during deployment advertisement regulatory actions.

Язык: Английский

Процитировано

51

Priority Areas for Adolescent Health Measurement DOI Creative Commons
Regina Guthold, Ann‐Beth Moller, Emmanuel Adebayo

и другие.

Journal of Adolescent Health, Год журнала: 2021, Номер 68(5), С. 888 - 898

Опубликована: Фев. 23, 2021

PurposeWe establish priority areas for adolescent health measurement and identify current gaps, aiming to focus resources on the most relevant data improve health.MethodsWe collected four critical inputs inform setting: perspectives of youth representatives, country priorities, disease burden, existing efforts. Health identified from were grouped, mapped, summarized according their frequency in inputs. Using a Delphi-like approach, international experts then selected core, expanded, context-specific all identified.ResultsAcross inputs, we 99 grouped them under six domains: policies, programs, laws; systems performance interventions; determinants; behaviors risks; subjective well-being; outcomes conditions. Areas frequently occurring mental weight status representatives' opinions; sexual reproductive HIV/AIDS policies perspectives; road injury, self-harm, skin diseases, disorders burden analysis; fertility initiatives. Considering 33 19 6 areas.ConclusionThe landscape is vast, covering large variety topics. The foci initiatives reviewed do not reflect important or country-level perspectives, burden. Based these propose set national global measurement.

Язык: Английский

Процитировано

40

Current status of use of big data and artificial intelligence in RMDs: a systematic literature review informing EULAR recommendations DOI Creative Commons
Joanna Kedra, Timothy R. D. J. Radstake, Aridaman Pandit

и другие.

RMD Open, Год журнала: 2019, Номер 5(2), С. e001004 - e001004

Опубликована: Июль 1, 2019

Objective To assess the current use of big data and artificial intelligence (AI) in field rheumatic musculoskeletal diseases (RMDs). Methods A systematic literature review was performed PubMed MEDLINE November 2018, with key words referring to data, AI RMDs. All original reports published English were analysed. mirror also outside RMDs on same number articles. The analysed, sources statistical methods used (traditional statistics, or both) collected. analysis compared findings within beyond Results Of 567 articles relating RMDs, 55 met inclusion criteria as well other medical fields. mean points 746 million (range 2000–5 billion) 9.1 billion 100 000–200 Data varied: 26 (47%) clinical, 8 (15%) biological 16 (29%) radiological. Both traditional analyse (respectively, 10 (18%) 45 (82%) 47 (85%) out RMDs). Machine learning represented 97% among these methods, most neural network (20/44 Conclusions Big types are varied heterogeneous. These will inform a European League Against Rheumatism taskforce

Язык: Английский

Процитировано

38

Consensus Parameter: Research Methodologies to Evaluate Neurodevelopmental Effects of Pubertal Suppression in Transgender Youth DOI Creative Commons
Diane Chen, John F. Strang, Victoria D. Kolbuck

и другие.

Transgender Health, Год журнала: 2020, Номер 5(4), С. 246 - 257

Опубликована: Июнь 9, 2020

Purpose: Pubertal suppression is standard of care for early pubertal transgender youth to prevent the development undesired and distressing secondary sex characteristics incongruent with gender identity. Preliminary evidence suggests improves mental health functioning. Given widespread changes in brain cognition that occur during puberty, a critical question whether this treatment impacts neurodevelopment. Methods: A Delphi consensus procedure engaged 24 international experts neurodevelopment, development, puberty/adolescence, neuroendocrinology, statistics/psychometrics identify priority research methodologies address empirical question: associated real-world neurocognitive sequelae? Recommended study approaches reaching 80% were included parameter. Results: The identified 160 initial expert recommendations, 44 which ultimately achieved consensus. Consensus design elements include following: minimum three measurement time points, staging at baseline, statistical modeling analyses, use analytic account heterogeneity, multiple comparison groups minimize limitations any one group. untreated matched on stage, cisgender (i.e., congruent) an independent sample from large-scale database. domains assessment includes: health, executive function/cognitive control, social awareness/functioning. Conclusion: An interdisciplinary team around primary methods assessing neurodevelopmental effects benefits and/or difficulties) youth.

Язык: Английский

Процитировано

36