Molecular Biology Reports, Год журнала: 2023, Номер 51(1)
Опубликована: Дек. 29, 2023
Язык: Английский
The Plant Cell, Год журнала: 2022, Номер 35(1), С. 24 - 66
Опубликована: Окт. 12, 2022
Climate change is a defining challenge of the 21st century, and this decade critical time for action to mitigate worst effects on human populations ecosystems. Plant science can play an important role in developing crops with enhanced resilience harsh conditions (e.g. heat, drought, salt stress, flooding, disease outbreaks) engineering efficient carbon-capturing carbon-sequestering plants. Here, we present examples research being conducted these areas discuss challenges open questions as call plant community.
Язык: Английский
Процитировано
113
PLANT PHYSIOLOGY, Год журнала: 2024, Номер 195(1), С. 170 - 189
Опубликована: Март 21, 2024
Abstract Drought and cold represent distinct types of abiotic stress, each initiating unique primary signaling pathways in response to dehydration temperature changes, respectively. However, a convergence at the gene regulatory level is observed where common set stress-responsive genes activated mitigate impacts both stresses. In this review, we explore these intricate networks, illustrating how plants coordinate stress signals into collective transcriptional strategy. We delve molecular mechanisms perception, signaling, activation pathways, with focus on insights gained from model species. By elucidating shared aspects plant responses drought cold, provide insight adaptive strategies plants, paving way for engineering stress-resilient crop varieties that can withstand changing climate.
Язык: Английский
Процитировано
52
Environmental Science & Technology, Год журнала: 2023, Номер 57(27), С. 9898 - 9924
Опубликована: Июнь 29, 2023
The present article critically and comprehensively reviews the most recent reports on smart sensors for determining glyphosate (GLP), an active agent of GLP-based herbicides (GBHs) traditionally used in agriculture over past decades. Commercialized 1974, GBHs have now reached 350 million hectares crops 140 countries with annual turnover 11 billion USD worldwide. However, rolling exploitation GLP last decades has led to environmental pollution, animal intoxication, bacterial resistance, sustained occupational exposure herbicide farm companies' workers. Intoxication these dysregulates microbiome-gut-brain axis, cholinergic neurotransmission, endocrine system, causing paralytic ileus, hyperkalemia, oliguria, pulmonary edema, cardiogenic shock. Precision agriculture, i.e., (information technology)-enhanced approach crop management, including a site-specific determination agrochemicals, derives from benefits materials (SMs), data science, nanosensors. Those typically feature fluorescent molecularly imprinted polymers or immunochemical aptamer artificial receptors integrated electrochemical transducers. Fabricated as portable wearable lab-on-chips, smartphones, soft robotics connected SM-based devices that provide machine learning algorithms online databases, they integrate, process, analyze, interpret massive amounts spatiotemporal user-friendly decision-making manner. Exploited ultrasensitive toxins, GLP, will become practical tools farmlands point-of-care testing. Expectedly, can be personalized diagnostics, real-time water, food, soil, air quality monitoring, control.
Язык: Английский
Процитировано
27
AoB Plants, Год журнала: 2023, Номер 15(4)
Опубликована: Июль 1, 2023
Abstract The increasing evaporative demand due to climate change will significantly affect the balance of carbon assimilation and water losses plants worldwide. development crop varieties with improved water-use efficiency (WUE) be critical for adapting agricultural strategies under predicted future climates. This review aims summarize most important leaf morpho-physiological constraints WUE in C3 identify gaps knowledge. From gain side WUE, discussed parameters are mesophyll conductance, carboxylation respiratory losses. traits affecting waterside this stomatal size density, control residual (cuticular bark conductance), nocturnal conductance hydraulic conductance. In addition, we impact anatomy crown architecture on both loss components WUE. There multiple possible targets understanding sources variability plants. We identified as greatest knowledge whole-plant assessments. Moreover, trichomes, canopy structure plants’ is still not well understood. a multi-trait approach urgently needed better dynamics optimization.
Язык: Английский
Процитировано
23
ACS Pharmacology & Translational Science, Год журнала: 2024, Номер 7(5), С. 1205 - 1236
Опубликована: Апрель 8, 2024
Glyphosate (GLP) is an active agent of GLP-based herbicides (GBHs), i.e., broad-spectrum and postemergent weedkillers, commercialized by Monsanto as, e.g., Roundup RangerPro formulants. The GBH crop spraying, dedicated to genetically engineered GLP-resistant crops, has revolutionized modern agriculture increasing the production yield. However, abusively administered GBHs' ingredients, GLP, polyoxyethyleneamine, heavy metals, have polluted environmental industrial areas far beyond farmlands, causing global contamination life-threatening risk, which led recent local bans use. Moreover, preclinical clinical reports demonstrated harmful impacts GLP other ingredients on gut microbiome, gastrointestinal tract, liver, kidney, endocrine, as well reproductive, cardiopulmonary systems, whereas carcinogenicity these remains controversial. Occupational exposure dysregulates hypothalamic–pituitary–adrenal axis, responsible for steroidogenesis endocrinal secretion, thus affecting hormonal homeostasis, functions reproductive organs, fertility. On hand, acute intoxication with GBH, characterized dehydration, oliguria, paralytic ileus, hypovolemic cardiogenic shock, pulmonary edema, hyperkalemia, metabolic acidosis, may occur fatally. As no antidote been developed poisoning so far, detoxification mainly symptomatic supportive requires intensive care based gastric lavage, extracorporeal blood filtering, intravenous lipid emulsion infusion. current review comprehensively discusses molecular physiological basics GLP- and/or GBH-induced diseases endocrine cardiopulmonary-, nephro-, hepatotoxicities, presented in studies case accidental or intentional ingestions most popular GBHs. Finally, they briefly describe future healthcare methods tools detection, determination, detoxification. Future electronically powered, decision-making, user-friendly devices targeting major GLP/GBH's modes actions, dysbiosis inhibition AChE, shall enable self-handled point-of-care professional-assisted evaluation harm followed rapid capturing xenobiotics body precise determining pathology-associated biomarkers levels.
Язык: Английский
Процитировано
11
Frontiers in Plant Science, Год журнала: 2024, Номер 15
Опубликована: Март 22, 2024
Abiotic stresses such as drought, salinity, and cold negatively affect plant growth crop productivity. Understanding the molecular mechanisms underlying responses to these stressors is essential for stress tolerance in crops. The hormone abscisic acid (ABA) significantly increased upon abiotic stressors, inducing physiological adapt regulate gene expression. Although many studies have examined components of established signaling pathways, few explored other unknown elements. This study aimed identify novel stress-responsive genes plants by performing a meta-analysis public RNA sequencing (RNA-Seq) data Arabidopsis thaliana , focusing on five ABA-related conditions (ABA, Salt, Dehydration, Osmotic, Cold). 216 paired datasets from was conducted, differentially expressed were identified introducing new metric, called TN [stress-treated (T) non-treated (N)] score. We revealed that 14 commonly upregulated 8 downregulated across all treatments, including some not previously associated with responses. On hand, regulated salt, dehydration, osmotic treatments exogenous ABA or stress, suggesting they may be involved response dehydration independent ABA. Our list candidate ABA-dependent ABA-independent These could valuable resources selecting genome editing targets potentially contribute discovery pathways plants.
Язык: Английский
Процитировано
6
Frontiers in Plant Science, Год журнала: 2022, Номер 13
Опубликована: Апрель 21, 2022
WHIRLIES are plant-specific proteins binding to DNA in plastids, mitochondria, and nucleus. They have been identified as significant components of nucleoids the organelles where they regulate structure diverse DNA-associated processes. also fulfil roles nucleus by interacting with telomers various transcription factors, among them members WRKY family. While most plants two WHIRLY proteins, additional evolved gene duplication some dicot families. All share a conserved domain responsible for ssDNA binding. Structural analyses revealed that form tetramers higher-order complexes upon DNA. An outstanding feature is parallel localization or three cell compartments. Because translocate from nucleus, excellent candidates transducing signals between allow coordinated activities different genomes. Developmental cues environmental factors control expression genes. Mutants reduced abundance gave insight into their multiple functionalities. In chloroplasts, reduction level leads changes replication, transcription, RNA processing, repair. Furthermore, chloroplast development, ribosome formation, photosynthesis impaired monocots. low coincides number cristae rate respiration. The involved plants’ resistance toward abiotic biotic stress. Plants levels show responsiveness such light drought. Consequently, because acclimation, accumulate reactive oxygen species under stress conditions. contrast, several plant overexpressing were shown higher pathogen attacks. By interactions organelle nuclear maybe comma can be inserted here? participation organelle–nucleus communication, proposed serve development coordinating processes at levels. It multifunctionality linked plasticity land develop function continuously changing environment.
Язык: Английский
Процитировано
27
Ecotoxicology and Environmental Safety, Год журнала: 2024, Номер 271, С. 115965 - 115965
Опубликована: Янв. 19, 2024
Glyphosate (GLP) and GLP-based herbicides (GBHs), such as polyethoxylated tallow amine-based GLP surfactants (GLP-SH), developed in the late 70′, have become most popular controversial agrochemicals ever produced. Nowadays, GBHs reached 350 million hectares of crops over 140 countries, with an annual turnover 5 billion 11 USD U.S.A. worldwide, respectively. Because highly efficient inhibitory activity targeted to 5-enolpyruvylshikimate-3-phosphate synthase pathway, present plants several bacterial strains, GLP-resistant crop-based genetic agricultural revolution has decreased famine improved costs quality living developing countries. However, this progress come at cost 50-year GBH overuse, leading environmental pollution, animal intoxication, resistance, sustained occupational exposure herbicide farm companies’ workers. According preclinical clinical studies covered review, poisoning GLP, GLP-SH, devastatingly affects gut microbiota microbiota-gut-brain (MGB) axis, dysbiosis gastrointestinal (GI) ailments, well immunosuppression inappropriate immunostimulation, cholinergic neurotransmission dysregulation, neuroendocrinal system disarray, neurodevelopmental neurobehavioral alterations. Herein, we mainly focus on contribution (GM) neurological impairments, e.g., stroke neurodegenerative neuropsychiatric disorders. The current review provides a comprehensive introduction GLP’s microbiological neurochemical activities, including deviation intestinal Firmicutes-to-Bacteroidetes ratio, acetylcholinesterase inhibition, excitotoxicity, mind-altering processes. Besides, it summarizes critically discusses recent case reports concerning harmful impacts GI tract, MGB nervous system. Finally, insightful comparison toxic effects caused by GBH-SH, is presented. To end, propose first-to-date survey intoxications these herbicides.
Язык: Английский
Процитировано
5
Опубликована: Фев. 27, 2025
Язык: Английский
Процитировано
0
Plant Breeding, Год журнала: 2025, Номер unknown
Опубликована: Март 19, 2025
ABSTRACT The challenge of feeding the world's growing population is impaired by declining arable land, water quality and erratic weather patterns due to climate change. Abiotic stresses such as drought, heat, salinity cold disrupt plant growth, reducing crop yields quality. Modern biotechnological tools including high‐throughput sequencing bioinformatics have enabled characterization stress responses through advanced “omics” technologies. Genomics, transcriptomics, proteomics, metabolomics epigenomics describe molecular mechanisms underlying tolerance. Integrating multi‐omics approaches provides a deeper understanding these mechanisms, addressing limitations single‐omics studies. combination data (genomics, proteomics metabolomics) identifies important biomarkers, regulatory networks genetic targets that enhance resilience. This information regarding plants crucial for genome‐assisted breeding (GAB) improve traits development climate‐resilient crops withstand environmental challenges. Therefore, researchers use pipelines productive crops, tolerance, solving global food security challenges caused change stressors. review discusses role omics technologies in describing explores how this applied resilience productivity, which leads improved crops. application combining develop next‐generation are capable thriving under adverse conditions, ensuring reliable safe supply future conditions.
Язык: Английский
Процитировано
0