Microchemical Journal, Год журнала: 2025, Номер unknown, С. 112787 - 112787
Опубликована: Янв. 1, 2025
Язык: Английский
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2023, Номер 291, С. 122340 - 122340
Опубликована: Янв. 8, 2023
Язык: Английский
Процитировано
57
Molecules, Год журнала: 2023, Номер 28(1), С. 335 - 335
Опубликована: Янв. 1, 2023
The abuse and residues of antibiotics have a great impact on the environment organisms, their determination has become very important. Due to low contents, varieties complex matrices, effective recognition, separation enrichment are usually required prior determination. Molecularly imprinted polymers (MIPs), kind highly selective polymer prepared via molecular imprinting technology (MIT), used widely in analytical detection antibiotics, as adsorbents solid-phase extraction (SPE) recognition elements sensors. Herein, recent advances MIPs for antibiotic residue analysis reviewed. Firstly, several new preparation techniques detecting briefly introduced, including surface imprinting, nanoimprinting, living/controlled radical polymerization, multi-template multi-functional monomer dummy template imprinting. Secondly, SPE modes based summarized, namely packed SPE, magnetic dispersive matrix extraction, microextraction, stir-bar sorptive pipette-tip SPE. Thirdly, basic principles MIP-based sensors three sensing modes, electrochemical sensing, optical mass also outlined. Fourthly, research progress molecularly SPEs (MISPEs) electrochemical/optical/mass various environmental food samples since 2018 comprehensively reviewed, sulfonamides, quinolones, β-lactams so on. Finally, application prospects
Язык: Английский
Процитировано
44
Advanced Healthcare Materials, Год журнала: 2023, Номер 13(1)
Опубликована: Сен. 24, 2023
Copper (Cu), an indispensable trace element within the human body, serving as intrinsic constituent of numerous natural enzymes, carrying out vital biological functions. Furthermore, nanomaterials exhibiting enzyme-mimicking properties, commonly known nanozymes, possess distinct advantages over their enzyme counterparts, including cost-effectiveness, enhanced stability, and adjustable performance. These advantageous attributes have captivated attention researchers, inspiring them to devise various Cu-based nanomaterials, such copper oxide, Cu metal-organic framework, CuS, explore potential in enzymatic catalysis. This comprehensive review encapsulates most recent advancements illuminating applications realm biochemistry. Initially, it is delved into emulation typical types achieved by nanomaterials. Subsequently, latest breakthroughs concerning nanozymes biochemical sensing, bacterial inhibition, cancer therapy, neurodegenerative diseases treatment discussed. Within this segment, also explored modulation nanozyme activity. Finally, a visionary outlook for future development presented.
Язык: Английский
Процитировано
42
Analytical Chemistry, Год журнала: 2024, Номер 96(16), С. 6417 - 6425
Опубликована: Апрель 12, 2024
Molecular imprinting-based surface-enhanced Raman scattering (MI-SERS) sensors have shown remarkable potential from an academic standpoint. However, their practical applications, especially in the detection of large-size protein (≥10 nm), face challenges due to lack versatile sensing strategies and nonspecific fouling matrix species. Herein, we propose a reporter inspector mechanism (RRIM) implemented on protein-imprinted polydopamine (PDA) layer coated SERS active substrate. In RRIM, after recognition, permeability PDA imprinted cavities undergoes changes that are scrutinized by molecules. Target proteins can specifically bind fully occupy cavities, whereas species cannot. Then, molecules with suitable size introduced serve as both inspectors recognition status inducers signal, which only penetrate through vacant nonspecifically filled cavities. Consequently, signal exclusively originate specific binding target proteins, while is curbed. The RRIM enables reproducible quantitation cyanobacteria-specific model phycocyanin, at level down 2.6 × 10
Язык: Английский
Процитировано
31
Journal of the American Chemical Society, Год журнала: 2024, Номер 146(11), С. 7594 - 7604
Опубликована: Март 11, 2024
The preservation of chirality during a transformation process, known as the "chiral memory" effect, has garnered significant attention across multiple research disciplines. Here, we first report retention original chiral structure dynamic covalent chemistry (DCC)-induced structural from porous organic cages into frameworks (COFs). A total six two-dimensional COFs constructed by entirely achiral building blocks were obtained through DCC-induced substitution linkers in homochiral cage (CC3-R or -S) using amine monomers. Homochirality these resulted construction 3-fold-symmetric benzene-1,3,5-methanimine cores with propeller-like configuration one single-handedness throughout cage-to-COF transformation. can be further utilized fluorescence sensors stationary phases for gas chromatography high enantioselectivity. present study thus highlighted great potential to expand scope functional materials via crystal-to-crystal memory effect.
Язык: Английский
Процитировано
28
Analytical Chemistry, Год журнала: 2024, Номер 96(3), С. 1380 - 1389
Опубликована: Янв. 10, 2024
In enantiomer recognition and separation, a highly enantioselective approach with universal applicability is urgently desired but hard to realize, especially in the case of chiral molecules. To resolve trade-off between enantioselectivity universality, glutathione (GSH) methylated cyclodextrins (MCD)-functionalized covalent organic framework (GSH-MCD COF) porosity abundant surfaces presented that was designed synthesized for separation various enantiomers. As expected, GSH-MCD COF can be used as stationary phases enantiomers, including aromatic alcohols, acids, amides, amino performance versatility even superior some widely commercial chromatographic columns. Furthermore, shows high rapid identification enantiomers metabolites when coupling Raman spectroscopy. Molecular simulations suggest provides confined microenvironment peptides dictates capability. This work strategy synthesize synergetic multichiral achieve separations recognitions complex samples.
Язык: Английский
Процитировано
26
ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown
Опубликована: Фев. 24, 2025
The year 2024 marks the 50th anniversary of discovery surface-enhanced Raman spectroscopy (SERS). Over recent years, SERS has experienced rapid development and became a critical tool in biomedicine with its unparalleled sensitivity molecular specificity. This review summarizes advancements challenges substrates, nanotags, instrumentation, spectral analysis for biomedical applications. We highlight key developments colloidal solid an emphasis on surface chemistry, hotspot design, 3D hydrogel plasmonic architectures. Additionally, we introduce innovations including those interior gaps, orthogonal reporters, near-infrared-II-responsive properties, along biomimetic coatings. Emerging technologies such as optical tweezers, nanopores, wearable sensors have expanded capabilities single-cell single-molecule analysis. Advances analysis, signal digitalization, denoising, deep learning algorithms, improved quantification complex biological data. Finally, this discusses applications nucleic acid detection, protein characterization, metabolite monitoring, vivo spectroscopy, emphasizing potential liquid biopsy, metabolic phenotyping, extracellular vesicle diagnostics. concludes perspective clinical translation SERS, addressing commercialization potentials tissue sensing imaging.
Язык: Английский
Процитировано
3
Talanta, Год журнала: 2023, Номер 268, С. 125283 - 125283
Опубликована: Окт. 14, 2023
Язык: Английский
Процитировано
38
Coordination Chemistry Reviews, Год журнала: 2023, Номер 501, С. 215564 - 215564
Опубликована: Дек. 1, 2023
Язык: Английский
Процитировано
36
Food Chemistry, Год журнала: 2023, Номер 429, С. 136822 - 136822
Опубликована: Июль 8, 2023
Язык: Английский
Процитировано
31