Mitigating
climate
change
in
soil
ecosystems
involves
complex
plant
and
microbial
processes
regulating
carbon
pools
flows.
Here,
we
advocate
for
the
use
of
microbiome
interventions
to
help
increase
stocks
curb
greenhouse
gas
emissions
from
managed
soils.
Direct
include
introduction
strains,
consortia,
phage,
transplants,
whereas
indirect
managing
conditions
or
additives
modulate
community
composition
its
activities.
Approaches
using
microbially
catalyzed
increasing
inputs
plants,
promoting
organic
matter
(SOM)
formation,
reducing
SOM
turnover
production
diverse
gases.
Marginal
degraded
soils
may
provide
greatest
opportunities
enhancing
global
stocks.
Among
many
knowledge
gaps
this
field,
crucial
influencing
transformation
plant-derived
into
identity
microbes
activities
impacting
transformation.
As
a
critical
step
forward,
encourage
broadening
current
widespread
screening
potentially
beneficial
microorganisms
encompass
functions
relevant
stimulating
Moreover,
developing
these
interventions,
must
consider
potential
ecological
ramifications
uncertainties,
such
as
incurred
by
homogenous
inoculants
need
site-specificity
given
extreme
variation
among
habitats.
Incentivization
implementation
at
large
spatial
scales
could
effectively
harness
increases
stocks,
helping
mitigate
impacts
change.
Nature Biotechnology,
Год журнала:
2023,
Номер
42(5), С. 715 - 718
Опубликована: Июль 27, 2023
Abstract
Studies
using
16S
rRNA
and
shotgun
metagenomics
typically
yield
different
results,
usually
attributed
to
PCR
amplification
biases.
We
introduce
Greengenes2,
a
reference
tree
that
unifies
genomic
databases
in
consistent,
integrated
resource.
By
inserting
sequences
into
whole-genome
phylogeny,
we
show
metagenomic
data
generated
from
the
same
samples
agree
principal
coordinates
space,
taxonomy
phenotype
effect
size
when
analyzed
with
tree.
Nature Communications,
Год журнала:
2023,
Номер
14(1)
Опубликована: Июнь 8, 2023
Factors
driving
microbial
community
composition
and
diversity
are
well
established
but
the
relationship
with
functioning
is
poorly
understood,
especially
at
large
scales.
We
analysed
biodiversity
metrics
distribution
of
potential
functional
groups
along
a
gradient
increasing
land-use
perturbation,
detecting
over
79,000
bacterial
25,000
fungal
OTUs
in
715
sites
across
24
European
countries.
found
lowest
less-disturbed
environments
(woodlands)
compared
to
grasslands
highly-disturbed
(croplands).
Highly-disturbed
contain
significantly
more
chemoheterotrophs,
harbour
higher
proportion
plant
pathogens
saprotrophs,
have
less
beneficial
symbionts
woodlands
extensively-managed
grasslands.
Spatial
patterns
communities
predicted
functions
best
explained
when
interactions
among
major
determinants
(vegetation
cover,
climate,
soil
properties)
considered.
propose
guidelines
for
environmental
policy
actions
argue
that
taxonomical
should
be
considered
simultaneously
monitoring
purposes.
ACS Chemical Neuroscience,
Год журнала:
2023,
Номер
14(10), С. 1717 - 1763
Опубликована: Май 8, 2023
Gut
microbiota
includes
a
vast
collection
of
microorganisms
residing
within
the
gastrointestinal
tract.
It
is
broadly
recognized
that
gut
and
brain
are
in
constant
bidirectional
communication,
which
its
metabolic
production
major
component,
form
so-called
microbiome–brain
axis.
Disturbances
homeostasis
caused
by
imbalance
their
functional
composition
activities,
known
as
dysbiosis,
cause
dysregulation
these
pathways
trigger
changes
blood–brain
barrier
permeability,
thereby
causing
pathological
malfunctions,
including
neurological
disorders.
In
turn,
can
affect
structure
function
through
autonomic
nervous
system
regulating
motility,
intestinal
transit
secretion,
permeability.
Here,
we
examine
data
from
CAS
Content
Collection,
largest
published
scientific
information,
analyze
publication
landscape
recent
research.
We
review
advances
knowledge
related
to
human
microbiome,
complexity
functionality,
communication
with
central
system,
effect
axis
on
mental
health.
discuss
correlations
between
various
diseases,
specifically
also
explore
metabolites
regard
impact
associated
diseases.
Finally,
assess
clinical
applications
gut-microbiota-related
substances
development
pipelines.
hope
this
serve
useful
resource
understanding
current
emerging
field
an
effort
further
solving
remaining
challenges
fulfilling
potential.
Soil Biology and Biochemistry,
Год журнала:
2024,
Номер
193, С. 109382 - 109382
Опубликована: Март 12, 2024
Soil
is
an
extremely
complex
and
dynamic
matrix,
in
part,
due
to
the
wide
diversity
of
organisms
living
within
it.
organic
matter
(SOM)
fundamental
substrate
on
which
delivery
ecosystem
services
depends,
providing
metabolic
fuel
drive
soil
function.
As
such,
studying
metabolome
(the
concentration
low
molecular
weight
metabolites),
as
a
subset
SOM,
holds
potential
greatly
expand
our
understanding
behaviour,
fate,
interaction
functional
significance
small
molecules
soil.
Encompassing
range
chemical
classes
(including
amino
acids,
peptides,
lipids
carbohydrates)
large
number
individual
(ca.
n
=
105
106),
resultant
(indirect)
output
several
layers
biological
hierarchy,
namely
metagenome,
metatranscriptome
metaproteome.
it
may
also
provide
support
validation
for
these
"multi-omics"
datasets.
We
present
case
increased
use
untargeted
metabolomics
biochemistry,
particularly
furthering
functions
driving
SOM
composition
biogeochemical
cycling.
Further,
we
discuss
scale
challenge
terms
metabolite
extraction,
analysis
interpretation
plant-soil-microbial
systems.
Lastly,
highlight
key
knowledge
gaps
currently
limit
metabolomic
approaches
better
understand
processes,
including:
(i)
datasets;
(ii)
source,
emission
fate
soil-derived
volatile
compounds
(VOCs),
(iii)
assessing
temporal
fluxes
metabolites,
(iv)
monitoring
ecological
interactions
rhizosphere.
While
application
science
still
its
relative
infancy,
importance
biochemical
system
relation
regulation,
management
underpinning
further
elucidating
links
between
organisms,
well
ability
community
process
cycle
nutrients.
Natural Product Reports,
Год журнала:
2024,
Номер
41(6), С. 885 - 904
Опубликована: Янв. 1, 2024
In
this
review
we
discuss
emerging
functional
metabolomics
strategies
and
their
potential
use
to
reveal
mechanistic
insights
in
large-scale
natural
product
discovery
studies.
