Polysaccharide degradation by the Bacteroidetes: mechanisms and nomenclature DOI Creative Commons

Lauren S. McKee,

Sabina Leanti La Rosa, Bjørge Westereng

и другие.

Environmental Microbiology Reports, Год журнала: 2021, Номер 13(5), С. 559 - 581

Опубликована: Май 26, 2021

The Bacteroidetes phylum is renowned for its ability to degrade a wide range of complex carbohydrates, trait that has enabled dominance in many diverse environments. best studied species inhabit the human gut microbiome and use polysaccharide utilization loci (PULs), discrete genetic structures encode proteins involved sensing, binding, deconstruction, import target glycans. In environmental species, degradation tightly coupled phylum-exclusive type IX secretion system (T9SS), which used certain enzymes linked gliding motility. addition, within specific these two adaptive systems (PULs T9SS) are intertwined, with PUL-encoded being secreted by T9SS. Here, we discuss most noteworthy PUL non-PUL mechanisms confer rapid capabilities We also acknowledge literature showcasing examples PULs rapidly expanding developing set assumptions can be hard track back original findings. Therefore, present simple universal description conserved functions how they determined, while proposing common nomenclature describing their components, simplify discussion understanding systems.

Язык: Английский

The links between gut microbiota and obesity and obesity related diseases DOI Open Access

Jiafeng Geng,

Qingqiang Ni, Wei Sun

и другие.

Biomedicine & Pharmacotherapy, Год журнала: 2022, Номер 147, С. 112678 - 112678

Опубликована: Фев. 5, 2022

The obesity epidemic has become a global public health crisis in recent years and is continuing to worsen at an alarming rate. However, the pathophysiological mechanisms involved development of obesity-related diseases are still being unraveled. In past ten years, gut microbiota been identified as crucial player affecting onset progression diseases, especially with respect changes its composition metabolites during progression. Herein, we summarize roles microbiota’s metabolite play related diseases. Furthermore, discuss potential therapeutic treatments that can be used modulate microbiome target relevant metabolic pathways

Язык: Английский

Процитировано

224

Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance DOI Creative Commons
Jotham Suez,

Yotam Cohen,

Rafael Valdés‐Mas

и другие.

Cell, Год журнала: 2022, Номер 185(18), С. 3307 - 3328.e19

Опубликована: Авг. 19, 2022

Язык: Английский

Процитировано

223

Understanding the gut microbiota and sarcopenia: a systematic review DOI
Chaoran Liu, Wing‐Hoi Cheung,

Jie Li

и другие.

Journal of Cachexia Sarcopenia and Muscle, Год журнала: 2021, Номер 12(6), С. 1393 - 1407

Опубликована: Сен. 14, 2021

Язык: Английский

Процитировано

221

Multiple functions of flagellar motility and chemotaxis in bacterial physiology DOI Creative Commons
Rémy Colin, Bin Ni, Leanid Laganenka

и другие.

FEMS Microbiology Reviews, Год журнала: 2021, Номер 45(6)

Опубликована: Июль 2, 2021

Most swimming bacteria are capable of following gradients nutrients, signaling molecules and other environmental factors that affect bacterial physiology. This tactic behavior became one the most-studied model systems for signal transduction quantitative biology, underlying molecular mechanisms well characterized in Escherichia coli several bacteria. In this review, we focus primarily on less understood aspect chemotaxis, namely its physiological relevance individual cells populations. As evident from multiple recent studies, even same species flagellar motility chemotaxis might serve roles, depending conditions. Among these, finding sources nutrients more generally locating niches optimal growth appear to be major functions which could explain many chemoeffector preferences as gene regulation. Chemotaxis also enhance efficiency colonization by motile bacteria, involves intricate interplay between collective behaviors trade-offs motility. Finally, play roles including swarming, biofilm formation autoaggregation, their interactions with animal plant hosts.

Язык: Английский

Процитировано

212

Polysaccharide degradation by the Bacteroidetes: mechanisms and nomenclature DOI Creative Commons

Lauren S. McKee,

Sabina Leanti La Rosa, Bjørge Westereng

и другие.

Environmental Microbiology Reports, Год журнала: 2021, Номер 13(5), С. 559 - 581

Опубликована: Май 26, 2021

The Bacteroidetes phylum is renowned for its ability to degrade a wide range of complex carbohydrates, trait that has enabled dominance in many diverse environments. best studied species inhabit the human gut microbiome and use polysaccharide utilization loci (PULs), discrete genetic structures encode proteins involved sensing, binding, deconstruction, import target glycans. In environmental species, degradation tightly coupled phylum-exclusive type IX secretion system (T9SS), which used certain enzymes linked gliding motility. addition, within specific these two adaptive systems (PULs T9SS) are intertwined, with PUL-encoded being secreted by T9SS. Here, we discuss most noteworthy PUL non-PUL mechanisms confer rapid capabilities We also acknowledge literature showcasing examples PULs rapidly expanding developing set assumptions can be hard track back original findings. Therefore, present simple universal description conserved functions how they determined, while proposing common nomenclature describing their components, simplify discussion understanding systems.

Язык: Английский

Процитировано

206