Unmasking SARS-CoV-2’s coagulation conspiracy: the role of Spike

Trends in Immunology, Год журнала: 2024, Номер unknown

Опубликована: Сен. 1, 2024

Язык: Английский

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Targeting fibrin in COVID-19

Nature Reviews Drug Discovery, Год журнала: 2024, Номер unknown

Опубликована: Сен. 27, 2024

Язык: Английский

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New Challenges and Perspectives in Neurology and Autonomic Disorders: A Leap Forward

Journal of Personalized Medicine, Год журнала: 2024, Номер 14(10), С. 1063 - 1063

Опубликована: Окт. 16, 2024

“Nothing in life is to be feared, it only understood [...]

Язык: Английский

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COVID-19 Lung Injury: Unique and Familiar Aspects of Pathophysiology

Applied Sciences, Год журнала: 2024, Номер 14(23), С. 11048 - 11048

Опубликована: Ноя. 27, 2024

Acute lung injury (ALI), diagnosed clinically as acute respiratory distress syndrome (ARDS), refers to a spectrum of inflammatory processes culminating in increased permeability the pulmonary alveolar–capillary barrier and impaired gas exchange. The pandemic caused by novel coronavirus, SARS-CoV-2, has raised questions similarities differences between COVID-19 ALI other etiologies. This review summarizes current knowledge regarding pathophysiology draws comparisons latter infectious etiologies ALI. Indeed, severe is characterized unique array disease mechanisms including suppression interferon responses, widespread inflammasome activation, altered leukocyte phenotypes, hyperactive thrombotic activity. Moreover, these manifest clinical progression, which further differentiates from viral pathogens such SARS, MERS, influenza. These features bear important implications for future therapeutic strategies.

Язык: Английский

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Association of systemic inflammation and long-term dysfunction in COVID-19 patients: a prospective cohort

Psychoneuroendocrinology, Год журнала: 2024, Номер 172, С. 107269 - 107269

Опубликована: Дек. 25, 2024

Язык: Английский

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