Unmasking SARS-CoV-2’s coagulation conspiracy: the role of Spike

Trends in Immunology, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

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Targeting fibrin in COVID-19

Nature Reviews Drug Discovery, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 27, 2024

Language: Английский

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New Challenges and Perspectives in Neurology and Autonomic Disorders: A Leap Forward

Journal of Personalized Medicine, Journal Year: 2024, Volume and Issue: 14(10), P. 1063 - 1063

Published: Oct. 16, 2024

“Nothing in life is to be feared, it only understood [...]

Language: Английский

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COVID-19 Lung Injury: Unique and Familiar Aspects of Pathophysiology

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(23), P. 11048 - 11048

Published: Nov. 27, 2024

Acute lung injury (ALI), diagnosed clinically as acute respiratory distress syndrome (ARDS), refers to a spectrum of inflammatory processes culminating in increased permeability the pulmonary alveolar–capillary barrier and impaired gas exchange. The pandemic caused by novel coronavirus, SARS-CoV-2, has raised questions similarities differences between COVID-19 ALI other etiologies. This review summarizes current knowledge regarding pathophysiology draws comparisons latter infectious etiologies ALI. Indeed, severe is characterized unique array disease mechanisms including suppression interferon responses, widespread inflammasome activation, altered leukocyte phenotypes, hyperactive thrombotic activity. Moreover, these manifest clinical progression, which further differentiates from viral pathogens such SARS, MERS, influenza. These features bear important implications for future therapeutic strategies.

Language: Английский

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Association of systemic inflammation and long-term dysfunction in COVID-19 patients: a prospective cohort

Psychoneuroendocrinology, Journal Year: 2024, Volume and Issue: 172, P. 107269 - 107269

Published: Dec. 25, 2024

Language: Английский

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