Gut microbiota reshapes the TNBC immune microenvironment: Emerging immunotherapeutic strategies DOI Creative Commons
Mingyao Huang, Yikai Zhang,

Zhaoji Chen

и другие.

Pharmacological Research, Год журнала: 2025, Номер 215, С. 107726 - 107726

Опубликована: Апрель 4, 2025

Triple-negative breast cancer (TNBC) is an aggressive subtype of with limited treatment options and poor prognosis. The gut microbiota, a diverse community microorganisms in the gastrointestinal tract, plays crucial role regulating immune responses through gut-immune axis. Recent studies have highlighted its significant impact on TNBC progression efficacy immunotherapies. This review examines interactions between microbiota system TNBC, focusing key cells pathways involved tumor immunity. It also explores modulation strategies, including probiotics, prebiotics, dietary interventions, fecal transplantation, as potential methods to enhance immunotherapeutic outcomes. Understanding these mechanisms offers promising avenues for improving patient prognosis TNBC.

Язык: Английский

Gut microbiota reshapes the TNBC immune microenvironment: Emerging immunotherapeutic strategies DOI Creative Commons
Mingyao Huang, Yikai Zhang,

Zhaoji Chen

и другие.

Pharmacological Research, Год журнала: 2025, Номер 215, С. 107726 - 107726

Опубликована: Апрель 4, 2025

Triple-negative breast cancer (TNBC) is an aggressive subtype of with limited treatment options and poor prognosis. The gut microbiota, a diverse community microorganisms in the gastrointestinal tract, plays crucial role regulating immune responses through gut-immune axis. Recent studies have highlighted its significant impact on TNBC progression efficacy immunotherapies. This review examines interactions between microbiota system TNBC, focusing key cells pathways involved tumor immunity. It also explores modulation strategies, including probiotics, prebiotics, dietary interventions, fecal transplantation, as potential methods to enhance immunotherapeutic outcomes. Understanding these mechanisms offers promising avenues for improving patient prognosis TNBC.

Язык: Английский

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