Chitosan-based Schiff base polymer derived from acetyl triazolyl uracil: Synthesis, characterization, evaluation of antimicrobial and antioxidant activities, and density functional theory calculations
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
unknown, С. 140327 - 140327
Опубликована: Янв. 1, 2025
Язык: Английский
Thiadiazole chitosan conjugates as a novel cosmetic ingredient for rinse-off hair conditioners: design, formulation, characterization and in silico-molecular docking studies
BMC Chemistry,
Год журнала:
2025,
Номер
19(1)
Опубликована: Апрель 19, 2025
Recently,
chitosan
derivatives,
as
eco-sustainable
and
renewable
products,
have
been
recorded
to
be
highly
effective
toward
cosmetics
with
potent
biological
activity.
The
main
core
of
this
research
is
develop
an
organic
hair
conditioner
(OHC)
based
on
two
chitosan-thiadiazole
conjugates,
chitosan-(ethylthio‑thiadiazole)
(CH-ETD)
chitosan-(benzylthio‑thiadiazole)
(CH-BTD),
natural
fragrances.
A
series
nine
OHC
formulae
were
prepared
(CH1-CH3
for
OHC,
E1-E3
CH-ETD
B1-B3
CH-BTD
OHC)
characterized
their
visual
examination,
pH,
thermal
stability,
dirt
dispersion,
moisturizing
time,
percentage
solid
content,
irritation,
rinsing,
combing,
the
luster.
results
showed
that
pH
values
all
4.2-4.7
which
considered
acceptable
avoid
skin
irritation.
distinctive
film
surrounds
each
individual
shaft
in
treated
groups
when
compared
control
without
application
under
a
scanning
electron
microscope
SEM
magnification
power
100
μm.
Additionally,
every
single
clearly
covered,
group
exhibited
noticeable
issues
not
observed
groups,
no
signs
tangling.
Due
end-use
performance
properties
formulated
it
can
concluded
formulas
(CH,
E2,
B2)
best
efficacy;
easier
style,
detangle
hair,
retain
moisture,
very
thick,
cause
irritation
or
inflammation,
minimize
frizz,
create
protective
barrier
hair.
These
findings
collectively
validate
potential
formulations
coupled
perfumery
transformative
approach
care,
aligning
consumer
preferences
both
efficacy
environmental
sustainability.
Furthermore,
work,
docking
studies
conducted
provide
theoretical
proof
about
significant
roles
keratin
growth
cosmetic
applications
(skin).
Язык: Английский
Exploring the potent hydrolytic activity of chitosan-cerium complex microspheres resin for organophosphorus pesticide degradation
Heliyon,
Год журнала:
2024,
Номер
10(13), С. e33642 - e33642
Опубликована: Июнь 28, 2024
Chitosan
is
a
biocompatible,
non-toxic
and
renewable
natural
basic
polysaccharide
that
can
be
cross-linked
reacted
with
Ce(IV)
to
form
physiologically
active
chitosan-Ce(IV)
complex.
To
investigate
this
novel
complex
its
potential
hydrolyze
phosphate
ester
bonds,
chitosan-cerium
microspheres
resin
(CS-CCMR)
was
prepared
from
chitosan
ceric
ammonium
nitrate
by
reversed-phase
suspension
cross-linking
polymerization.
CS-CCMR
characterized,
ability
disodium
p-nitrobenzene
(PNPP2Na)
organophosphorus
pesticides
investigated,
the
hydrolytic
mechanism
explored.
composed
of
dark
yellow
smooth
surfaces
dense
pores.
It
found
contained
4.507
mg/g
Ce(IV),
indicating
coordination
polymerization
between
successful.
The
presence
in
confirmed
multiple
analytical
methods
it
mediated
nitrogen
atom
amino
group
oxygen
hydroxyl
chitosan.
shown
efficiently
hydrolyzed
bonds
PNPP2Na
five
pesticides.
Hydrolysis
potentially
accomplished
charge
neutralization
nucleophilic
substitution.
parathion
degradation
involves
modification
nitro
give
aminoparathion,
followed
cleavage
P–O
bond
generate
diazinphos.
Consequently,
exhibits
great
efficiency
for
hydrolysis
expected
developed
as
an
agent
reduce
possibility
contamination
fruit
vegetable
drinks
Язык: Английский
Copper‐Catalyzed Chemoselective Synthesis of Pyrazolo‐Sulfonamide: Impact of Solvent on Nitro‐pyrazole Reactivity
European Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 21, 2024
Abstract
This
study
presents
a
copper‐catalyzed,
solvent‐dependent
method
for
the
rapid
and
efficient
synthesis
of
N
‐pyrazolo‐sulfonamides
directly
from
nitro‐pyrazole
sulfonyl
hydrazide
under
microwave
conditions.
The
reaction
exhibits
notable
solvent
effects
in
pyrazole's
reactivity.
ionic
liquid
DBU‐AcOH
triggered
reactivity
4‐nitro‐pyrazole,
whereas
PEG
proceeded
selectively
at
3‐
&
5‐positions
pyrazole.
Key
applications
this
include
gram‐scale
pyrazolo‐sulfonamide,
sulfaphenazole
analogue
sulfonamide
nucleoside.
Язык: Английский