Recent trends in catalytic sp³ C–H functionalization of heterocycles

Organic & Biomolecular Chemistry, Год журнала: 2020, Номер 18(4), С. 606 - 617

Опубликована: Янв. 1, 2020

In this mini-review, we attempt to highlight gaps in existing techniques for sp³ C–H activation adjacent heterocycles.

Язык: Английский

---

Iron-Catalyzed Coupling of Methyl N-Heteroarenes with Primary Alcohols: Direct Access to E-Selective Olefins

Organic Letters, Год журнала: 2019, Номер 21(18), С. 7514 - 7518

Опубликована: Авг. 30, 2019

An efficient Fe-catalyzed system is reported for direct α-olefination of methyl-substituted N-heteroarenes with primary alcohols. The catalytic dehydrogenative coupling enables a series functionalized E-olefinated N-heteroaromatics excellent selectivity (>99%). Initial mechanistic studies including deuterium-labeling experiments provide evidence the participation benzylic C-H/D bond

Язык: Английский

---

Aerobic Copper-Catalyzed Synthesis of Benzimidazoles from Diaryl- and Alkylamines via Tandem Triple C–H Aminations

ACS Catalysis, Год журнала: 2018, Номер 8(3), С. 2242 - 2246

Опубликована: Фев. 6, 2018

Through radical-induced tandem triple C–H aminations with free amines as the aminating agents, we herein present a precedent on aerobic copper-catalyzed synthesis of 5-diarylamino benzimidazoles, class optoelectronic device analogues by combining two molecules diarylamines and one molecule alkylamine in single operation. The developed chemistry proceeds merits natural abundant copper/O2 catalyst system, readily available feedstocks, broad substrate scope, good functional group tolerance, exclusive regio- chemoselectivity, high step atom efficiency, which offers an important basis for further construction products that are inaccessible or difficult to prepare existing methods employing catalytic amination strategy.

Язык: Английский

---

Iridium Supported on Phosphorus‐Doped Porous Organic Polymers: Active and Recyclable Catalyst for Acceptorless Dehydrogenation and Borrowing Hydrogen Reaction

Advanced Synthesis & Catalysis, Год журнала: 2019, Номер 361(24), С. 5695 - 5703

Опубликована: Окт. 22, 2019

Abstract Iridium‐on‐phosphorus‐doped porous organic polymers (POP−Ir) were developed by anchoring simple iridium onto the skeleton of through coordination bonds. This POP−Ir catalyst, which was thoroughly characterized means EDS, SEM, TEM, XRD, XPS, and FT‐IR, revealed excellent catalytic activity for reaction diphenyl phosphinamide with benzyl alcohols borrowing hydrogen strategy acceptorless dehydrogenation wide functional group tolerance. Moreover, this catalyst could be simply recovered reused at least five times without a significant loss activity, considerable application prospects. The mechanism investigated to further understand system transformations. Overall, has shown high reusability in between phosphinamides alcohols. magnified image

Язык: Английский

---

The synthesis and structure of pyridine-oxadiazole iridium complexes and catalytic applications: Non-coordinating-anion-tuned selective C N bond formation

Chinese Chemical Letters, Год журнала: 2019, Номер 31(3), С. 701 - 705

Опубликована: Авг. 28, 2019

Язык: Английский

---