European Journal of Cell Biology,
Год журнала:
2024,
Номер
103(2), С. 151417 - 151417
Опубликована: Май 6, 2024
Nowadays,
it
is
an
established
concept
that
the
capability
to
reach
a
specialised
cell
identity
via
differentiation,
as
in
case
of
multi-
and
pluripotent
stem
cells,
not
only
determined
by
biochemical
factors,
but
also
physical
aspects
microenvironment
play
key
role;
interpreted
through
force-based
signalling
pathway
called
mechanotransduction.
However,
intricate
ties
between
elements
involved
mechanotransduction,
such
extracellular
matrix,
glycocalyx,
membrane,
integrin
adhesion
complexes,
Cadherin-mediated
cell/cell
adhesion,
cytoskeleton,
nucleus,
are
still
far
from
being
understood
detail.
Here
we
report
what
currently
known
about
these
general
their
specific
interplay
context
cells.
We
furthermore
merge
this
overview
more
comprehensive
picture,
aims
cover
whole
mechanotransductive
cell/microenvironment
interface
regulation
chromatin
structure
nucleus.
Ultimately,
with
review
outline
current
picture
cues
epigenetic
how
processes
might
contribute
dynamics
fate.
Advanced Functional Materials,
Год журнала:
2023,
Номер
33(26)
Опубликована: Март 24, 2023
Abstract
Membrane
decorated
with
biocides
is
an
effective
way
to
suppress
biofilm
growth.
However,
their
immediate
biocidal
effect
usually
suffers
from
a
significant
decline
due
the
irreversible
consumption
of
biocides.
Here,
smart
nanofiltration
membrane
reported
rechargeable
antibacterial
capability
that
fabricated
by
facile
interfacial
polymerization
via
3‐aminophenylboronic
acid
and
trimesoyl
chloride
on
polysulfone
substrate.
Biocides
bearing
diol
groups
can
be
grafted
onto
surface
under
neutral/alkaline
condition
then
released
acidic
environment,
pH‐responsive
feature
boronate
ester
complexes.
The
resultant
exhibits
integrated
properties
fast
bacterial
inactivating
efficiency,
capability,
impressive
stability.
In
addition,
achieved
shows
remarkable
separation
efficiency
dye/monovalent
salt
system.
successful
fabrication
anti‐bacterial
property
provides
new
insights
into
development
sustainable
membranes.
Drug Delivery and Translational Research,
Год журнала:
2024,
Номер
14(11), С. 3032 - 3054
Опубликована: Апрель 13, 2024
Cell-mediated
nanoparticle
delivery
systems
(CMNDDs)
utilize
cells
as
carriers
to
deliver
the
drug-loaded
nanoparticles.
Unlike
traditional
drug
approaches,
CMNDDs
take
advantages
of
cell
characteristics,
such
homing
capabilities
stem
cells,
inflammatory
chemotaxis
neutrophils,
prolonged
blood
circulation
red
and
internalization
macrophages.
Subsequently,
can
easily
prolong
circulation,
cross
biological
barriers,
blood-brain
barrier
bone
marrow-blood
barrier,
rapidly
arrive
at
diseased
areas.
Such
advantageous
properties
make
promising
candidates
for
precision
targeting.
In
this
review,
we
summarize
recent
advances
in
fabrication
biomedical
applications.
Specifically,
ligand-receptor
interactions,
non-covalent
covalent
are
commonly
applied
constructing
vitro.
By
hitchhiking
macrophages,
monocytes,
platelets,
nanoparticles
be
internalized
or
attached
construct
vivo.
Then
highlight
application
treating
different
diseases,
cancer,
central
nervous
system
disorders,
lung
cardiovascular
with
a
brief
discussion
about
challenges
future
perspectives
end.
ACS Applied Materials & Interfaces,
Год журнала:
2024,
Номер
16(5), С. 5613 - 5626
Опубликована: Янв. 26, 2024
,
cells
reside
in
a
3D
porous
and
dynamic
microenvironment.
It
provides
biochemical
biophysical
cues
that
regulate
cell
behavior
physiological
pathological
processes.
In
the
context
of
fundamental
biology
research,
tissue
engineering,
cell-based
drug
screening
systems,
challenge
is
to
develop
relevant
European Journal of Cell Biology,
Год журнала:
2024,
Номер
103(2), С. 151417 - 151417
Опубликована: Май 6, 2024
Nowadays,
it
is
an
established
concept
that
the
capability
to
reach
a
specialised
cell
identity
via
differentiation,
as
in
case
of
multi-
and
pluripotent
stem
cells,
not
only
determined
by
biochemical
factors,
but
also
physical
aspects
microenvironment
play
key
role;
interpreted
through
force-based
signalling
pathway
called
mechanotransduction.
However,
intricate
ties
between
elements
involved
mechanotransduction,
such
extracellular
matrix,
glycocalyx,
membrane,
integrin
adhesion
complexes,
Cadherin-mediated
cell/cell
adhesion,
cytoskeleton,
nucleus,
are
still
far
from
being
understood
detail.
Here
we
report
what
currently
known
about
these
general
their
specific
interplay
context
cells.
We
furthermore
merge
this
overview
more
comprehensive
picture,
aims
cover
whole
mechanotransductive
cell/microenvironment
interface
regulation
chromatin
structure
nucleus.
Ultimately,
with
review
outline
current
picture
cues
epigenetic
how
processes
might
contribute
dynamics
fate.
