Advanced Synthesis & Catalysis,
Год журнала:
2019,
Номер
361(13), С. 3094 - 3101
Опубликована: Апрель 29, 2019
Abstract
The
first
example
of
CoCl
2
‐catalyzed
formal
[5+2]
oxidative
annulation
o
‐arylanilines
with
alkynes
was
developed,
giving
access
to
various
important
imine‐containing
dibenzo‐[
b
,
d
]azepine
scaffolds
through
sequential
C−C/C−N
bond
formation.
reaction
employs
catalytic
amount
manganese
and
oxygen
as
cooxidants,
features
a
broad
substrate
scope.
Preliminary
mechanistic
studies
suggested
that
C−H
activation
is
involved
in
the
rate‐determining
step.
Moreover,
both
internal
terminal
are
well
tolerated
this
transformation.
Besides,
regioselective
migratory
insertion
observed
when
using
substrates.
magnified
image
Chemical Society Reviews,
Год журнала:
2020,
Номер
49(15), С. 5310 - 5358
Опубликована: Янв. 1, 2020
This
review
highlights
the
developments
in
iron
and
cobalt
catalyzed
C(sp3)–H
bond
functionalization
reactions
with
emphasis
on
their
applications
organic
synthesis,
i.e.
natural
products
pharmaceuticals
synthesis
and/or
modification.
ACS Catalysis,
Год журнала:
2022,
Номер
12(6), С. 3452 - 3506
Опубликована: Март 3, 2022
Transition-metal-catalyzed
C–H
bond
functionalizations
have
had
an
enormous
influence
on
organic
synthesis
in
recent
times.
However,
the
use
of
low-abundance
4d
and
5d
metals
is
almost
inevitable,
they
are
high
demand.
This
will
be
a
cause
concern,
hence,
it
important
to
develop
methods
based
3d
metals,
which
widely
present
Earth's
crust.
In
this
regard,
metal
catalysts
or
their
precursors
for
catalysis,
general,
functionalizations,
particular,
has
gained
significant
momentum
The
major
development
catalytic
with
been
achieved
predominantly
strongly
coordinating
directing
groups
such
as
pyridyl,
pyrimidinyl,
pyrazolyl,
8-amino-quinolinyl
groups.
Thus,
prefunctionalization
substrates
these
necessary,
contradicts
step-
atom-economy
activation.
commonly
available
functional
aldehyde,
ketone,
carboxylic
acid,
amide,
hydroxy,
N-oxides
loosely
bind
through
weak-coordination.
These
weakly
orient
activate
regioselectively
without
need
preinstalled
Although
challenging,
contemporary
topic
actively
pursued
by
many
researchers
Through
article,
we
provide
comprehensive
overview
metal-catalyzed,
coordinating,
directing-group-enabled
reported
until
March
2021.
Journal of the American Chemical Society,
Год журнала:
2020,
Номер
142(20), С. 9510 - 9517
Опубликована: Апрель 25, 2020
An
asymmetric
hydroarylative
cyclization
of
enynes
involving
a
C–H
bond
cleavage
is
reported.
The
cobalt-catalyzed
cascade
generates
three
new
bonds
in
an
atom-economical
fashion.
products
were
obtained
excellent
yields
and
enantioselectivities
as
single
diastereo-
regioisomers.
Preliminary
mechanistic
studies
indicate
that
the
reaction
shows
no
intermolecular
crossover.
This
work
highlights
potential
cobalt
catalysis
functionalization
enantioselective
domino
reactivity.
Chemistry - A European Journal,
Год журнала:
2020,
Номер
26(44), С. 9749 - 9783
Опубликована: Июнь 18, 2020
Sequential,
domino
and
tandem
reactions
could
be
defined
as
a
sequence
of
synthetic
transformations
that
occur
one
after
the
other,
in
same
reaction
flask.
This
Review
highlights
recent
advances
at
overlap
two
worlds:
transition-metal
mediated
C-H
activation
trigger
cascade
reaction,
for
heterocycles
synthesis.
To
shed
some
light
on
this
intricate
"middle-earth",
focus
was
put
mechanism
rather
than
type
metal
or
chronological
order
reaction.
The
aim
is
to
separate,
then
highlight,
true
initiated
by
activation,
compared
other
examples
functionalization
heterocycle
syntheses.
Chemistry - An Asian Journal,
Год журнала:
2021,
Номер
16(5), С. 443 - 459
Опубликована: Янв. 15, 2021
Metal
carbenes
play
a
pivotal
role
in
transition-metal-catalyzed
synthetic
transfer
reactions.
The
metal
carbene
is
generated
either
from
diazo
compound
through
facile
extrusion
of
N2
with
catalyst
or
situ
other
sources
like
triazoles,
pyriodotriazoles,
sulfoxonium
ylides
and
iodonium-ylide.
On
the
hand,
Co(III),
Rh(III)
&
Ir(III)-catalyzed
C-H
functionalizations
have
been
well
established
as
key
step
to
enable
construction
various
transformations.
Interestingly,
recent
years,
merging
these
two
concepts
activation
migratory
insertion
gained
much
attention,
particular
group
9
metal-catalyzed
arene
precursors
via
insertion.
In
this
review,
we
summarize
advances
direct
alkylation/alkenylation/arylation
also
discuss
intermediates
within
catalytic
cycles.
Advanced Synthesis & Catalysis,
Год журнала:
2020,
Номер
362(8), С. 1602 - 1650
Опубликована: Янв. 29, 2020
Abstract
Manganese‐catalysed
reactions
have
attracted
great
attention
recently
due
to
the
high
relative
abundance
and
cheap
eco‐friendly
behaviour.
Applications
of
manganese
catalysis
in
cross‐dehydrogenative
coupling
are
among
hottest
areas
since
90%
contributions
very
recent.
Dehydrogenation
alcohols
using
Mn‐pincer
systems
is
highly
explored
nowadays
for
cross‐coupling
synthesise
a
variety
products
Mn‐catalysed
C−H
activation,
radical
applied
dehydrogenative
couplings
various
synthons.
This
review
focuses
on
synthesis
synthetically
as
well
biologically
important
motifs
such
carbonyl
compounds,
olefins,
nitrogen
heterocycles,
amines,
imines,
etc.
manganese‐catalysed
reactions.
magnified
image
European Journal of Organic Chemistry,
Год журнала:
2021,
Номер
2021(26), С. 3690 - 3720
Опубликована: Июнь 15, 2021
Abstract
Development
in
the
area
of
acceptorless
dehydrogenation
(AD)
and
borrowing
hydrogen
(BH)
catalysis
emerge
as
one
potential
tools
for
various
C−C
C‐heteroatom
bond
forming
reactions.
Alcohols,
which
are
important
lignocellulosic
biomass
products,
act
pivotal
electrophilic
coupling
partners
such
processes
interestingly
only
H
2
or
O
is
eliminated
a
byproduct.
Initially,
was
developed
by
use
noble
metal
catalysts.
Recently,
base
metals
Mn,
Fe,
Co,
Ni
proved
to
be
environmentally
benign
inexpensive
alternatives
application
AD
BH
methods.
This
transition
catalyzed
approaches
also
allow
access
toward
plethora
structurally
heterocyclic
molecules
via
atom
economical
strategy.
Herein,
we
summarize
current
rising
expansion
heterocycles
synthesis
through
hydrogenation
Angewandte Chemie International Edition,
Год журнала:
2020,
Номер
59(38), С. 16409 - 16413
Опубликована: Июнь 11, 2020
Abstract
We
report
a
cobalt‐catalyzed
hydroacylation
of
1,6‐enynes
with
exogenous
aldehydes
in
domino
sequence
to
construct
enantioenriched
ketones.
The
products
were
obtained
good
yields
excellent
regio‐,
diastereo‐,
and
enantioselectivity.
Furthermore,
the
chiral
served
as
valuable
precursors
access
complex
spirocyclic
scaffolds
three
contiguous
stereocenters.
asymmetric
process
exhibited
no
C−H
crossover
KIE,
thus
indicating
that
bond
cleavage
was
not
involved
turnover‐limiting
step.
Chemical Communications,
Год журнала:
2020,
Номер
56(87), С. 13287 - 13300
Опубликована: Янв. 1, 2020
Allylic
substitution,
pioneered
by
the
work
of
Tsuji
and
Trost,
has
been
an
invaluable
tool
in
synthesis
complex
molecules
for
decades.
An
attractive
alternative
to
allylic
substitution
is
direct
functionalization
C-H
bonds
unactivated
alkenes,
thereby
avoiding
need
prefunctionalization.
Significant
early
advances
were
made
using
palladium
catalysis.
However,
Pd-catalyzed
reactions
are
generally
limited
terminal
olefins
with
stabilized
nucleophiles.
Insights
from
Li,
Cossy,
Tanaka
demonstrated
utility
RhCpx
catalysts
functionalization.
Since
these
initial
reports,
a
number
key
intermolecular
Co-,
Rh-,
Ir-catalyzed
have
reported,
offering
significant
complementarity
reactions.
Herein,
we
report
summary
recent
via
group
IX-metal
π-allyl
complexes.
Mechanism-driven
development
new
highlighted,
potential
future
developments
discussed.
