Advanced Synthesis & Catalysis,
Год журнала:
2019,
Номер
361(13), С. 3094 - 3101
Опубликована: Апрель 29, 2019
Abstract
The
first
example
of
CoCl
2
‐catalyzed
formal
[5+2]
oxidative
annulation
o
‐arylanilines
with
alkynes
was
developed,
giving
access
to
various
important
imine‐containing
dibenzo‐[
b
,
d
]azepine
scaffolds
through
sequential
C−C/C−N
bond
formation.
reaction
employs
catalytic
amount
manganese
and
oxygen
as
cooxidants,
features
a
broad
substrate
scope.
Preliminary
mechanistic
studies
suggested
that
C−H
activation
is
involved
in
the
rate‐determining
step.
Moreover,
both
internal
terminal
are
well
tolerated
this
transformation.
Besides,
regioselective
migratory
insertion
observed
when
using
substrates.
magnified
image
Catalysis Science & Technology,
Год журнала:
2020,
Номер
11(2), С. 444 - 458
Опубликована: Дек. 10, 2020
Manganese-catalyzed
C–H
activation
has
become
an
emerging
area
in
organic
chemistry.
These
efficient
and
eco-friendly
manganese
catalysed
reactions
provides
new
opportunities
the
field
of
synthetic
Organic Letters,
Год журнала:
2022,
Номер
24(40), С. 7288 - 7293
Опубликована: Окт. 4, 2022
A
ruthenium-catalyzed
peri-selective
C-H
activation
and
annulation
of
1-naphthols
with
CF3-substituted
imidoyl
sulfoxonium
ylides
that
uses
hydroxyl
as
a
weakly
coordinating
directing
group
is
disclosed.
The
strategy
provides
facile
practical
route
to
diverse
trifluoromethyl-containing
2,3-dihydrobenzo[de]chromen-2-amines
high
efficiency.
Notable
advantages
this
protocol
include
readily
available
materials,
excellent
regioselectivity,
good
functional
compatibility,
scalability.
Organic Letters,
Год журнала:
2020,
Номер
22(19), С. 7480 - 7485
Опубликована: Сен. 16, 2020
An
efficient
cobalt-catalyzed
[4
+
2]
annulation
of
hydrazones
and
1,3-diynes
has
been
developed
for
the
synthesis
3-alkynylated
isoquinolines
engaging
2-aminopyridine
as
a
traceless
bidentate
directing
group.
The
strategy
successfully
extended
3,3′-biisoquinoline
moieties
via
both
one-pot
well
sequential
approaches.
utilization
group
with
an
inexpensive
earth-abundant
cobalt-catalyst
under
operationally
simple
reaction
conditions
makes
present
transformation
more
valuable
appealing.
Organic & Biomolecular Chemistry,
Год журнала:
2020,
Номер
18(38), С. 7460 - 7466
Опубликована: Янв. 1, 2020
Direct
carbonylation
of
the
C-H
bond
is
a
great
tool
for
installing
carbonyl
group
in
wide
variety
substrates.
This
review
summarizes
methodologies
using
cobalt-catalyzed
functionalization
approach.
Despite
fact
that
have
been
known
since
Murahashi's
report
1955,
this
area
still
underdeveloped,
particularly
C(sp3)-H
bond.
Organic Letters,
Год журнала:
2021,
Номер
23(12), С. 4624 - 4629
Опубликована: Июнь 9, 2021
Co(III)-catalyzed
highly
regio-
and
stereoselective
direct
C6
olefination
of
2-pyridones
with
alkynes
has
been
developed
the
assistance
chelation.
Upon
variation
reaction
conditions,
react
well
diaryl
via
a
olefination/directing
group
migration
pathway
to
give
tetrasubstituted
6-vinyl-2-pyridones,
but
C6-H
terminal
works
effectively
afford
only
C6-olefinated
2-pyridones.
A
judicious
choice
solvent
an
additive
is
crucial
for
catalysis.
The
protocols
feature
100%
atom
economy,
excellent
site
selectivity,
high
stereoselectivity,
ample
substrate
scope,
good
compatibility
functional
groups.
Synthetic
applications
are
demonstrated,
experimental
studies
density
theory
calculations
conducted
gain
mechanistic
insight
into
two
transformations.
Chemical Communications,
Год журнала:
2019,
Номер
55(92), С. 13840 - 13843
Опубликована: Янв. 1, 2019
A
Cp*CoIII-catalyzed
arene
C–H
bond
amidation/annulation
of
benzamides
was
developed
to
afford
quinazolinone
derivatives
in
one-pot
with
high
yields
and
broad
substrate
scope.
Organic Letters,
Год журнала:
2020,
Номер
22(7), С. 2720 - 2723
Опубликована: Март 17, 2020
An
efficient
method
for
the
synthesis
of
3-hydroxymethyl
isoindolinones
via
cobalt-catalyzed
C(sp2)-H
carbonylation
phenylglycinol
derivatives
using
picolinamide
as
a
traceless
directing
group
is
demonstrated.
The
reaction
proceeds
in
presence
commercially
available
cobalt(II)
tetramethylheptanedionate
catalyst
and
employs
DIAD
"CO"
surrogate.
This
synthetic
route
offers
broad
substrate
scope,
excellent
regioselectivity,
full
preservation
original
stereochemistry.
Besides,
developed
provides
pathway
accessing
valuable
enantiopure
3-substituted
isoindolinone
derivatives.
