Review of application of the I₂ and dimethyl sulfoxide combined reagent system to aryl methyl ketones for diverse transformations

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(9), С. 2665 - 2692

Опубликована: Янв. 1, 2024

The synthesis of small molecules and complex scaffolds is one the most important topics in organic synthesis.

Язык: Английский

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The clean preparation of multisubstituted pyrroles under metal- and solvent-free conditions

Green Chemistry, Год журнала: 2019, Номер 22(1), С. 118 - 122

Опубликована: Ноя. 29, 2019

A practical method for the clean preparation of multisubstituted pyrroles via an iodine-catalyzed multicomponent reaction under metal- and solvent-free conditions was developed. In gram-scale synthesis, can be easily collected through simple extraction.

Язык: Английский

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Four-component synthesis of 3-aminomethylated imidazoheterocycles in EtOH under catalyst-free, oxidant-free and mild conditions

Green Chemistry, Год журнала: 2021, Номер 23(12), С. 4430 - 4434

Опубликована: Янв. 1, 2021

The 3-aminomethylated imidazoheterocycles were efficiently synthesized in one-step via a four-component reaction of equimolar cheap and commercially available reactants at ambient temperature under catalyst-, oxidant-, base-free mild conditions.

Язык: Английский

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Transition-metal-free selective pyrimidines and pyridines formation from aromatic ketones, aldehydes and ammonium salts

Green Chemistry, Год журнала: 2019, Номер 21(19), С. 5201 - 5206

Опубликована: Янв. 1, 2019

Pyrimidines and pyridines could be selectively formed from aromatic ketones, aldehydes ammonium salts under transition-metal-free conditions.

Язык: Английский

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An environmentally benign multi-component reaction: regioselective synthesis of fluorinated 2-aminopyridines using diverse properties of the nitro group

Green Chemistry, Год журнала: 2019, Номер 21(6), С. 1505 - 1516

Опубликована: Янв. 1, 2019

A procedure was developed for the synthesis of fluorinated 2-aminopyridines based on reactions 1,1-enediamines, benzaldehydes and 1,3-dicarbonyl compounds.

Язык: Английский

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Access to 2-arylquinazolines via catabolism/reconstruction of amino acids with the insertion of dimethyl sulfoxide

Chemical Communications, Год журнала: 2021, Номер 57(44), С. 5414 - 5417

Опубликована: Янв. 1, 2021

Quinazoline skeletons are synthesized by amino acid catabolism/reconstruction combined with the insertion/cyclization of dimethyl sulfoxide for first time.

Язык: Английский

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NNO Pincer Ligand-Supported Palladium(II) Complexes: Direct Synthesis of Quinazolines via Acceptorless Double Dehydrogenative Coupling of Alcohols

Organometallics, Год журнала: 2022, Номер 41(11), С. 1314 - 1324

Опубликована: Май 20, 2022

A sustainable approach for the synthesis of substituted quinazolines by sequential acceptorless dehydrogenative coupling 2-aminobenzyl alcohol with alcohols using new Pd(II)-NNO pincer-type complexes as catalysts was reported. Air-stable palladium(II) general formula [Pd(L)(PPh3)] (where L = 4-substituted methyl-2-pyrrolyl benzhydrazone ligands) were synthesized, and their compositions recognized analytical spectral methods (Fourier transform infrared (FT-IR), NMR, high-resolution mass spectrometry (HRMS)). Single-crystal X-ray crystallography confirmed tridentate coordination ligands existence square-planar geometry around metal ion. wide range quinazoline derivatives synthesized from double dehydrogenation benzyl 1.5 mol % catalyst loading a maximum 93% yield. The formation aminobenzaldehyde benzaldehyde intermediates via reaction control experiments.

Язык: Английский

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Three-Component Synthesis of 2-Substituted Quinolines and Benzo[f]quinolines Using Tertiary Amines as the Vinyl Source

The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(5), С. 2952 - 2960

Опубликована: Фев. 20, 2023

A metal-free method for the construction of 2-substituted quinolines and benzo[f]quinolines from aromatic amines, aldehydes, tertiary amines has been demonstrated. Cheap readily available acted as vinyl source. new pyridine ring was selectively formed via [4 + 2] condensation that promoted by ammonium salt under neutral conditions an oxygen atmosphere. This strategy provided a route preparation various quinoline derivatives with different substituents at ring, which provides possibility further modification.

Язык: Английский

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Modular Synthesis of Tetrasubstituted Pyrroles through a Four-Component Cyclization Strategy Using Ammonium Salt as the Nitrogen Source

The Journal of Organic Chemistry, Год журнала: 2023, Номер 88(3), С. 1533 - 1544

Опубликована: Янв. 19, 2023

A four-component synthesis of tetrasubstituted pyrroles was developed under metal-free conditions. The pyrrole ring formed in one pot through [2 + 1 1] condensation using ammonium salt as the nitrogen source. In this strategy, 1,4-naphthoquinones and maleimides were used versatile C2 fragments to provide substituted benzo[f]isoindole-4,9-diones pyrrolo[3,4-c]pyrrole-1,3-diones, respectively. This work is highlighted by source, readily available starting materials multibond formation (two C–C two C–N bonds) a single operation.

Язык: Английский

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In situ growing CNTs/TiO2 heterojunction on MXene sheets for enhanced microwave absorption via multiple electron transfer paths and polarization

Ceramics International, Год журнала: 2023, Номер 50(1), С. 2282 - 2292

Опубликована: Ноя. 2, 2023

Язык: Английский

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