Pharmaceutics,
Год журнала:
2020,
Номер
12(4), С. 392 - 392
Опубликована: Апрель 24, 2020
The
transdermal
delivery
of
sparingly
soluble
drugs
is
challenging
due
to
the
need
for
a
drug
carrier.
In
past
few
decades,
ionic
liquid
(IL)-in-oil
microemulsions
(IL/O
MEs)
have
been
developed
as
potential
carriers.
By
focusing
on
biocompatibility,
we
report
an
IL/O
ME
that
designed
enhance
solubility
and
drug,
acyclovir.
prepared
MEs
were
composed
hydrophilic
IL
(choline
formate,
choline
lactate,
or
propionate)
non-aqueous
polar
phase
surface-active
oleate)
surfactant
in
combination
with
sorbitan
laurate
continuous
oil
phase.
selected
ILs
all
biologically
active
ions.
Optimized
pseudo
ternary
diagrams
indicated
formed
thermodynamically
stable,
spherically
shaped,
nano-sized
(<100
nm)
droplets.
An
vitro
permeation
study,
using
pig
skin,
showed
significantly
enhanced
acyclovir
ME.
A
Fourier
transform
infrared
spectroscopy
study
reduction
skin
barrier
function
Finally,
irritation
high
cell
survival
rate
(>90%)
compared
Dulbecco's
phosphate-buffered
saline,
indicates
biocompatibility
Therefore,
conclude
may
be
promising
nano-carrier
drugs.
Biotechnology for Biofuels,
Год журнала:
2019,
Номер
12(1)
Опубликована: Дек. 1, 2019
Abstract
The
implementation
of
biorefineries
based
on
lignocellulosic
materials
as
an
alternative
to
fossil-based
refineries
calls
for
efficient
methods
fractionation
and
recovery
the
products.
focus
biorefinery
concept
utilisation
biomass
has
shifted,
from
design
more
or
less
energy-driven
biorefineries,
much
versatile
facilities
where
chemicals
energy
carriers
can
be
produced.
sugar-based
platform
requires
pretreatment
materials,
which
very
recalcitrant,
improve
further
processing
through
enzymatic
hydrolysis,
other
downstream
unit
operations.
This
review
summarises
development
in
field
(and
some
extent,
fractionation)
various
materials.
number
publications
indicates
that
plays
a
important
role
realised
full
scale.
traditional
methods,
example,
steam
(explosion),
organosolv
hydrothermal
treatment
are
covered
review.
In
addition,
rapidly
increasing
interest
chemical
employing
ionic
liquids
deep-eutectic
solvents
discussed
reviewed.
It
concluded
huge
variation
makes
it
difficult
find
general
process
biorefinery.
Therefore,
is
define
“the
best
pretreatment”
method.
end,
this
depends
proposed
application,
any
recommendation
suitable
method
must
thorough
techno-economic
evaluation.
Advanced Functional Materials,
Год журнала:
2021,
Номер
31(42)
Опубликована: Июль 23, 2021
Abstract
Excessive
and
unwarranted
administration
of
antibiotics
has
invigorated
the
evolution
multidrug‐resistant
microbes.
There
is,
therefore,
an
urgent
need
for
advanced
active
compounds.
Ionic
liquids
with
short‐lived
ion‐pair
structures
are
highly
tunable
have
diverse
applications.
Apart
from
their
unique
physicochemical
features,
newly
discovered
biological
activities
ionic
fascinated
biochemists,
microbiologists,
medical
scientists.
In
particular,
antimicrobial
properties
opened
new
vistas
in
overcoming
current
challenges
associated
combating
antibiotic‐resistant
pathogens.
Discussions
regarding
liquid
derivatives
monomeric
polymeric
forms
presented
here.
The
mechanism
parameters
that
affect
activities,
such
as
chain
length,
cation/anion
type,
cation
density,
polymerization,
considered.
potential
applications
biomedical
arena,
including
regenerative
medicine,
biosensing,
drug/biomolecule
delivery,
to
stimulate
scientific
community
further
improve
efficacy
liquids.
Green Chemistry,
Год журнала:
2020,
Номер
22(23), С. 8116 - 8139
Опубликована: Янв. 1, 2020
This
critical
review
highlights
the
recent
advancements
of
using
biocompatible
ionic
liquids
as
“green”
designer
solvents
and/or
materials
to
overcome
limitations
caused
by
conventional
organic
solvents/materials
in
pharmaceutics
and
medicine.
Chemical Society Reviews,
Год журнала:
2023,
Номер
52(7), С. 2497 - 2527
Опубликована: Янв. 1, 2023
This
review
describes
the
most
recent
developments
in
materials
design
and
advanced
features
of
ionogels,
as
well
their
emerging
biomedical
applications.
ACS Applied Materials & Interfaces,
Год журнала:
2021,
Номер
13(17), С. 20735 - 20745
Опубликована: Апрель 26, 2021
Conductive
stretchable
hydrogels
and
ionogels
consisting
of
ionic
liquids
can
have
interesting
application
as
wearable
strain
pressure
sensors
bioelectrodes
due
to
their
soft
nature
high
conductivity.
However,
a
severe
stability
problem
because
water
evaporation,
whereas
are
not
biocompatible
or
even
toxic.
Here,
we
demonstrate
self-adhesive,
stretchable,
nonvolatile,
eutectogels
that
always
form
conformal
contact
skin
during
body
movement
along
with
biopotential
electrodes
for
precise
health
monitoring.
The
consist
deep
eutectic
solvent
has
conductivity,
waterborne
polyurethane
is
an
elastomer,
tannic
acid
adhesive.
They
elongation
at
break
178%,
conductivity
0.22
mS/cm,
adhesion
force
12.5
N/m
skin.
be
used
accurately
monitor
joint
breath.
piezoresistive
sensitivity
284.4
kPa–1
precisely
detect
subtle
physical
movements
like
arterial
pulses,
which
provide
vital
cardiovascular
information.
Moreover,
the
nonvolatile
epidermal
physiological
signals,
such
electrocardiogram
(ECG)
electromyogram
(EMG).
Chemical Reviews,
Год журнала:
2023,
Номер
123(15), С. 9204 - 9264
Опубликована: Июль 7, 2023
Ionic
conductors
(ICs)
find
widespread
applications
across
different
fields,
such
as
smart
electronic,
ionotronic,
sensor,
biomedical,
and
energy
harvesting/storage
devices,
largely
determine
the
function
performance
of
these
devices.
In
pursuit
developing
ICs
required
for
better
performing
sustainable
cellulose
appears
an
attractive
promising
building
block
due
to
its
high
abundance,
renewability,
striking
mechanical
strength,
other
functional
features.
this
review,
we
provide
a
comprehensive
summary
regarding
fabricated
from
cellulose-derived
materials
in
terms
fundamental
structural
features
cellulose,
design
fabrication
techniques
engineering,
main
properties
characterization,
diverse
applications.
Next,
potential
cellulose-based
relieve
increasing
concern
about
electronic
waste
within
frame
circularity
environmental
sustainability
future
directions
be
explored
advancing
field
are
discussed.
Overall,
hope
review
can
unique
perspectives
on
application
advanced
thereby
encourage
utilization
cellulosic
toward
Fuel,
Год журнала:
2023,
Номер
344, С. 128102 - 128102
Опубликована: Март 15, 2023
Global
warming
triggered
by
greenhouse
gas
(GHG)
emissions,
particularly
carbon
dioxide
(CO2),
significantly
influences
climate
change
and
has
become
a
common
environmental
issue
recently.
The
current
amine-based
technologies
(ABTs)
for
CO2
capture
(CAPCO2)
have
high
energy
demand,
low
absorption,
desorption
rates,
are
less
environmentally
sustainable
due
to
emissions
of
volatile
solvents.
Therefore,
the
development
friendly
CAPCO2
materials
and/or
processes
is
growing
area
research.
utilization
ionic
liquids
(ILs)
recently
attracted
attention.
unique
characteristics
ILs,
such
as
their
vapor
pressure
affinity
well
volatility
make
them
viable
substitute
existing
processes.
This
work
provides
comprehensive
overview
accomplishments
challenges
during
use
ILs
CAPCO2.
Review
also
outlines
mechanisms
with
at
molecular
level,
properties
characterization
CO2/IL
systems,
effect
operating
conditions
on
uptake
(UPCO2)
capacity
ILs.
It
emphasizes
impact
cations,
anions,
functional
groups
solubility
((SCO2))
in
biodegradability
toxicity
Additionally,
recent
advances
IL
membrane
technology
considered.
Lastly,
contribution
simulations
create
assess
was
reviewed.
Protic
aprotic
shown
outstanding
efficiency
UPCO2.
interactions
between
anionic
part
enhance
UPCO2
outperform
traditional
organic
Functionalized
(FUNILs)
tuned
groups,
supported
membranes
(SILMs)
reversible
(RILs)
improved
promising
capturing
process
from
industrial
streams
even
under
partial
pressure.
relative
importance
chemical
breakdown
constituents
(cation–anion
interfacial
structuring)
different
temperatures
unclear,
more
research
this
required
better
inform
design
new
review
proper/systematic
guideline
help
manufacturers
engineers
high-capacity
appropriate
