ACS Catalysis,
Год журнала:
2023,
Номер
13(17), С. 11399 - 11421
Опубликована: Авг. 15, 2023
The
oxidative
addition
(OA)
of
organic
electrophiles
to
Pd(0)
is
a
fundamental
step
in
organopalladium
chemistry
and
plays
key
role
palladium-catalyzed
cross-coupling
reactions.
This
perspective
summarizes
selected
mechanistic
studies
the
Pd(0)-to-Pd(II)
OA
process
involving
halides
pseudohalides
with
focus
on
systems
relevant
catalytic
results
are
organized
according
nature
supporting
ligands,
extracting
general
trends,
describing
most
examples.
formation
active
species
from
precatalysts
surveyed,
as
well
influence
different
that
could
be
present
under
conditions
process,
providing
guidelines
facilitate
understanding
improvement
Chemical Reviews,
Год журнала:
2021,
Номер
122(3), С. 3637 - 3710
Опубликована: Дек. 15, 2021
The
principles
of
green
chemistry
(GC)
can
be
comprehensively
implemented
in
synthesis
pharmaceuticals
by
choosing
no
solvents
or
(preferably
water),
alternative
reaction
media,
and
consideration
one-pot
synthesis,
multicomponent
reactions
(MCRs),
continuous
processing,
process
intensification
approaches
for
atom
economy
final
waste
reduction.
GC's
execution
performed
using
a
holistic
design
the
active
pharmaceutical
ingredient's
(API)
life
cycle,
minimizing
hazards
pollution,
capitalizing
resource
efficiency
technique.
Thus,
presented
review
accounts
comprehensive
exploration
metrics,
an
appropriate
implication
those
ideas
each
step
schemes,
from
raw
material
to
intermediate
product's
into
scalable
industry-based
production.
For
real-life
examples,
we
have
discussed
series
established
generic
pharmaceuticals,
starting
with
materials,
intermediates
corresponding
pharmaceuticals.
Researchers
industries
thoughtfully
instigated
control
reduction
protect
environment.
We
extensively
significant
relevant
cascade
MCRs,
intensification,
which
may
contribute
future
sustainable
APIs.
Advanced Materials,
Год журнала:
2021,
Номер
33(16)
Опубликована: Март 12, 2021
Abstract
To
improve
the
performance
of
metallic
catalysts,
alloying
provides
an
efficient
methodology
to
design
state‐of‐the‐art
materials.
As
emerging
functional
materials,
rare‐earth
metal
compounds
can
integrate
unique
orbital
structure
and
catalytic
behavior
rare
earth
elements
into
Such
containing
alloy
catalysts
proffer
opportunity
tailor
electronic
properties,
tune
charged
carrier
transport,
synergize
surface
reactivity,
which
are
expected
significantly
stability
catalysis.
Despite
its
significance,
there
only
few
reviews
on
alloys
or
related
topics.
This
review
summarizes
composition,
synthesis,
applications
in
field
Subsequent
comprehensively
summarizing
constructively
discussing
existing
work,
challenges
possibilities
future
research
compound
materials
evaluated.
Chemical Reviews,
Год журнала:
2022,
Номер
122(6), С. 6749 - 6794
Опубликована: Фев. 24, 2022
Dipolar
aprotic
and
ethereal
solvents
comprise
just
over
40%
of
all
organic
utilized
in
synthetic
organic,
medicinal,
process
chemistry.
Unfortunately,
many
the
common
"go-to"
are
considered
to
be
"less-preferable"
for
a
number
environmental,
health,
safety
(EHS)
reasons
such
as
toxicity,
mutagenicity,
carcinogenicity,
or
practical
handling
flammability
volatility.
Recent
legislative
changes
have
initiated
implementation
restrictions
on
use
commonly
employed
dipolar
dimethylformamide
(DMF)
N-methyl-2-pyrrolidinone
(NMP),
ethers
1,4-dioxane.
Thus,
with
growing
legislative,
EHS,
societal
pressures,
need
identify
implement
alternative
that
greener,
safer,
more
sustainable
has
never
been
greater.
Within
this
review,
ubiquitous
nature
is
discussed
respect
physicochemical
properties
made
them
so
appealing
chemists.
An
overview
current
being
imposed
discussed.
A
variety
alternative,
garnered
attention
past
decade
then
examined,
case
studies
examples
where
less-preferable
successfully
replaced
safer
highlighted.
Finally,
general
guidance
solvent
selection
replacement
included
Supporting
Information
review.
Organic & Biomolecular Chemistry,
Год журнала:
2021,
Номер
19(12), С. 2558 - 2577
Опубликована: Янв. 1, 2021
This
review
highlights
recent
advances
in
metal-
and
biocatalyzed
transformations,
the
synthesis
of
APIs
other
biologically
active
compounds,
when
employing
deep
eutectic
solvents
water
as
environmentally
responsible
solvents.
Abstract
As
of
December
2023,
the
use
common
solvent
N
,
‐dimethyl
formamide
(DMF)
will
be
restricted
in
European
Union
because
its
reproductive
health
hazard.
Industrial
facilities
must
comply
with
stricter
exposure
limits,
and
researchers
are
recommended
to
find
alternative
solvents.
Here
we
explain
restrictions
on
DMF,
which
disciplines
affected,
how
substitute
DMF
keep
research
development
commercially
relevant.
Chemical Reviews,
Год журнала:
2020,
Номер
121(3), С. 1582 - 1622
Опубликована: Дек. 22, 2020
Chlorinated
solvents
were
once,
and
in
many
places
are
still,
ubiquitous
chemistry
laboratories.
This
review
explores
the
properties
that
led
to
such
widespread
use,
why
there
is
now
an
increasing
drive
minimize
usage,
what
alternatives
currently
available.
Chemical Society Reviews,
Год журнала:
2020,
Номер
49(6), С. 1643 - 1652
Опубликована: Янв. 1, 2020
Recognizing
and
classifying
the
recently
appeared
reactivity
enabling
unconventional
solvents
is
main
objective
of
this
tutorial
review,
for
applications
in
field
C–H
bond
functionalization
reactions.
Journal of Materials Chemistry A,
Год журнала:
2020,
Номер
8(12), С. 5890 - 5899
Опубликована: Янв. 1, 2020
Solvent-exfoliated
CPP-based
photocatalysts
have
been
innovatively
used
for
photocatalytic
hydrogen
production
with
an
unprecedented
HER
of
up
to
303.7
mmol
h−1
g−1.
