Visible light-induced recyclable g-C₃N₄ catalyzed thiocyanation of C(sp²)–H bonds in sustainable solvents

Green Chemistry, Год журнала: 2021, Номер 23(10), С. 3677 - 3682

Опубликована: Янв. 1, 2021

A metal-free photocatalytic strategy for the preparation of thiocyanated heterocycles from inexpensive NH₄SCN has been developed using carbon nitride (g-C₃N₄) as a general heterogeneous catalyst.

Язык: Английский

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Recent Advances in Reactions Using Enaminone in Water or Aqueous Medium

Advanced Synthesis & Catalysis, Год журнала: 2022, Номер 364(9), С. 1508 - 1521

Опубликована: Апрель 8, 2022

Abstract Enaminones have in the past decade received renewed interest organic synthesis by acting as highly versatile building blocks. Particularly, featured amino and carbonyl group enaminone structure endow them with ability of tolerating water via hydrogen bonding effect. Thus, designing synthetic methods aqueous medium enaminones main blocks has extensive attention notable success. Based on our longstanding efforts interests chemistry, we review herein research advances participated medium. magnified image

Язык: Английский

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Recent advances in visible light-mediated chemical transformations of enaminones

Chinese Chemical Letters, Год журнала: 2023, Номер 35(2), С. 108977 - 108977

Опубликована: Авг. 26, 2023

Язык: Английский

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Electrochemical enaminone C–H thiolation/C–N amination cascade for thiazole synthesis and its diastereoselective dearomatization

Green Chemistry, Год журнала: 2022, Номер 24(13), С. 5058 - 5063

Опубликована: Янв. 1, 2022

The electrochemical annulation of enaminones/analogous enamines and thioureas providing 2-aminothiazoles has been realized. Modulating the electrolyte enables diastereoselective synthesis 4,5-dialkoxyl thiazolines by dearomatization.

Язык: Английский

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Recent advances in photochemical and electrochemically induced thiocyanation: a greener approach for SCN-containing compound formation

RSC Advances, Год журнала: 2022, Номер 12(10), С. 6214 - 6233

Опубликована: Янв. 1, 2022

Techniques utilizing photo- and electrochemically induced reactions have been developed to accelerate organic processes. These techniques use light or electrical energy (electron transfer) as a direct source without using an initiator reagent. Thiocyanates are found in biologically active pharmacological compounds can be converted into various functional groups. It is one of the most prominent scaffolds. Significant development electro-chemically thiocyanation procedures has made recent years for conception carbon-sulfur bonds synthesis pharmaceutically important molecules. This review discusses different driven C(sp

Язык: Английский

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Recent progress of direct thiocyanation reactions

Organic & Biomolecular Chemistry, Год журнала: 2022, Номер 20(33), С. 6508 - 6527

Опубликована: Янв. 1, 2022

Thiocyanation can introduce SCN groups into parent molecules for constructing SCN-containing small organic molecules. In this review, we summarize the research progress of direct thiocyanation in recent years.

Язык: Английский

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Electrochemical oxidative selenocyclization of olefinic amides towards the synthesis of iminoisobenzofurans

Organic Chemistry Frontiers, Год журнала: 2022, Номер 9(10), С. 2786 - 2791

Опубликована: Янв. 1, 2022

We introduced an electrochemical oxidative radical cascade cyclization of olefinic amides and diselenides without a transition-metal catalyst external oxidant. This selenocyclization reaction provided facile method to construct C–Se C–O bonds in one step.

Язык: Английский

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Iodine-Promoted Thioylation and Dicarbonylation of Enaminone α-C Sites: Synthesis of Fully Substituted Thiazoles via C═C Bond Cleavage

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(4), С. 2505 - 2515

Опубликована: Фев. 5, 2024

A novel iodine-promoted difunctionalization of α-C sites in enaminones was demonstrated as a means synthesizing variety fully substituted thiazoles by constructing C–C(CO), C–S, and C–N bonds. This transformation allows the realization unusual aryl C2 synthons simultaneously thioylation dicarbonylation sites. preliminary mechanistic study performed indicated that cleavage C═C bonds involves bicyclization/ring-opening oxidative coupling sequence.

Язык: Английский

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Electrochemical multicomponent [2+2+1] cascade cyclization of enaminones and primary amines towards the synthesis of 4-acylimidazoles

Chemical Communications, Год журнала: 2024, Номер 60(19), С. 2677 - 2680

Опубликована: Янв. 1, 2024

An electrochemical multicomponent [2+2+1] cascade cyclization of enaminones and primary amines towards the synthesis 4-acylimidazoles has been developed. In an undivided cell, can smoothly participate in this reaction to provide a series 1,2-disubstituted at room temperature. The avoids use both transition-metal catalysts oxidation reagents, which makes it more sustainable renewable.

Язык: Английский

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Visible-Light-Driven Multicomponent Cyclization by Trapping a 1,3-Vinylimine Ion Intermediate: A Direct Approach to Pyrimido[1,2-b]indazole Derivatives

Organic Letters, Год журнала: 2021, Номер 23(21), С. 8343 - 8347

Опубликована: Окт. 12, 2021

Here we develop a novel visible-light-driven three-component cyclization by trapping an 1,3-vinylimine ion intermediate for the direct synthesis of pyrimido[1,2-b]indazole derivatives from bromodifluoroacetic acid derivatives, enaminones, and 3-aminoindazoles under mild conditions. Notably, robust methodology provides valuable opportunity introduction aliphatic substituents enables good compatibility complex bioactive molecules. Furthermore, this is first example photoinduced multicomponent reaction employing as C1-synthon.

Язык: Английский

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