Nanotechnology–General Aspects: A Chemical Reduction Approach to the Synthesis of Nanoparticles

Molecules, Год журнала: 2023, Номер 28(13), С. 4932 - 4932

Опубликована: Июнь 22, 2023

The role of nanotechnology is increasingly important in our society. Through it, scientists are acquiring the ability to understand structure and properties materials manipulate them at scale atoms molecules. Nanomaterials forefront rapidly growing field nanotechnology. synthesis nanostructured materials, especially metallic nanoparticles, has attracted tremendous interest over past decade due their unique properties, making these excellent indispensable many areas human activity. These special can be attributed small size large specific surface area which very different from those bulk materials. Nanoparticles sizes shapes needed for applications, so a variety protocols required produce monodisperse nanoparticles with controlled morphology. purpose this review firstly introduce reader basic aspects related and, secondly, discuss greater detail. This article explains concepts nanotechnology, introduces methods synthesizing describes types, possible applications. Of proposed metal chemical reduction usually preferred because it easy perform, cost-effective, efficient, also allows control structural parameters through optimization conditions. Therefore, method discussed more detail—each factor by described detail, i.e., precursors, solvents, reducing agents, stabilizers. that used characterize nanomaterials described. Finally, based on available literature collection, shown how changing parameters/methods affects final characteristics nanoparticles.

Язык: Английский

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The role of selenium and nano selenium on physiological responses in plant: a review

Plant Growth Regulation, Год журнала: 2023, Номер 100(2), С. 409 - 433

Опубликована: Март 24, 2023

Язык: Английский

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Biogenic Selenium Nanoparticles in Biomedical Sciences: Properties, Current Trends, Novel Opportunities and Emerging Challenges in Theranostic Nanomedicine

Nanomaterials, Год журнала: 2023, Номер 13(3), С. 424 - 424

Опубликована: Янв. 19, 2023

Selenium is an important dietary supplement and essential trace element incorporated into selenoproteins with growth-modulating properties cytotoxic mechanisms of action. However, different compounds selenium usually possess a narrow nutritional or therapeutic window low degree absorption delicate safety margins, depending on the dose chemical form in which they are provided to organism. Hence, nanoparticles (SeNPs) emerging as novel diagnostic platform decreased toxicity capacity enhance biological Se-based compounds. Consistent exciting possibilities offered by nanotechnology diagnosis, treatment, prevention diseases, SeNPs useful tools current biomedical research exceptional benefits potential therapeutics, enhanced bioavailability, improved targeting, effectiveness against oxidative stress inflammation-mediated disorders. In view need for developing eco-friendly, inexpensive, simple, high-throughput agents that can also ally theranostic purposes exhibit negligible side effects, biogenic receiving special attention. The present manuscript aims be reference its kind providing readership thorough comprehensive review emphasizes current, yet expanding, field promise hold among selenium-derived products to, eventually, elicit future developments. First, recalls physiological importance oligo-element introduces unique biological, physicochemical, optoelectronic, catalytic Se nanomaterials. Then, it addresses significance nanosizing pharmacological activity (pharmacokinetics pharmacodynamics) cellular interactions SeNPs. Importantly, discusses detail role biosynthesized innovative personalized nanomedicine-based therapies. Finally, this explores ongoing context SARS-CoV-2 pandemic presents key prospects translational nanomedicine.

Язык: Английский

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A Review of the Antibacterial, Fungicidal and Antiviral Properties of Selenium Nanoparticles

Materials, Год журнала: 2023, Номер 16(15), С. 5363 - 5363

Опубликована: Июль 30, 2023

The resistance of microorganisms to antimicrobial drugs is an important problem worldwide. To solve this problem, active searches for components, approaches and therapies are being carried out. Selenium nanoparticles have high potential activity. relevance their application indisputable, which can be noted due the significant increase in publications on topic over past decade. This review research aims provide reader with up-to-date information properties selenium nanoparticles, including susceptible microorganisms, mechanisms action bacteria effect nanoparticle describes most complete antiviral, antibacterial antifungal effects nanoparticles.

Язык: Английский

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Exploring the antimicrobial, antioxidant, anticancer, biocompatibility, and larvicidal activities of selenium nanoparticles fabricated by endophytic fungal strain Penicillium verhagenii

Scientific Reports, Год журнала: 2023, Номер 13(1)

Опубликована: Июнь 3, 2023

Herein, four endophytic fungal strains living in healthy roots of garlic were used to produce selenium nanoparticles (Se-NPs) via green synthesis. Penicillium verhagenii was found be the most efficient Se-NPs producer with a ruby red color that showed maximum surface plasmon resonance at 270 nm. The as-formed crystalline, spherical, and well-arranged without aggregation, ranged from 25 75 nm size zeta potential value -32 mV, indicating high stability. Concentration-dependent biomedical activities P. verhagenii-based observed, including promising antimicrobial activity against different pathogens (Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Staphylococcus aureus, Candida albicans, C. glabrata, tropicalis, parapsilosis) minimum inhibitory concentration (MIC) 12.5-100 µg mL-1. biosynthesized antioxidant DPPH-scavenging percentages 86.8 ± 0.6% 1000 mL-1 decreased 19.3 4.5% 1.95 Interestingly, also anticancer PC3 MCF7 cell lines IC50 225.7 3.6 283.8 7.5 mL-1, respectively while it is remaining biocompatible normal WI38 Vero lines. Additionally, synthesized effective instar larvae medical insect, Aedes albopictus mortality 85.1 3.1, 67.2 1.2, 62.10 1.4, 51.0 1.0% 50 for I, II, III, IV-instar larva, respectively. These data highlight efficacy cost-effective eco-friendly synthesis applications.

Язык: Английский

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Antifungal Activity of Selenium Nanoparticles Obtained by Plant-Mediated Synthesis

Antibiotics, Год журнала: 2023, Номер 12(1), С. 115 - 115

Опубликована: Янв. 8, 2023

The continuous need to satisfy world food demand has led the search for new alternatives combat economic losses in agriculture caused by phytopathogenic fungi. These organisms cause plant diseases, reducing their productivity and decreasing fruit quality. Among tools being explored is nanotechnology. Nanoparticles with antimicrobial properties could be an excellent alternative address this problem. In work, selenium nanoparticles (SeNPs) were obtained using extracts of Amphipterygium glaucum leaves (SeNPs-AGL) Calendula officinalis flowers (SeNPs-COF). Characterization SeNPs was performed ability as antifungal agents against two commercially relevant pathogenic fungi, Fusarium oxysporum Colletotrichum gloeosporioides, evaluated. Assays different concentrations (0, 0.25, 0.5, 1.0, 1.7 mg/mL). It observed that both had activity pathogens at 0.25 mg/mL above. SeNPs-AGL demonstrated better smaller size (around 8.0 nm) than SeNPs-COF (134.0 nm). FTIR analysis evidenced existence functional groups constitute types SeNPs. There are factors have considered such nanoparticle phytochemical composition used, these may affect bioavailability.

Язык: Английский

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Selenium Nanoparticles: Green Synthesis and Biomedical Application

Molecules, Год журнала: 2023, Номер 28(24), С. 8125 - 8125

Опубликована: Дек. 15, 2023

Selenium nanoparticles (SeNPs) are extremely popular objects in nanotechnology. "Green" synthesis has special advantages due to the growing necessity for environmentally friendly, non-toxic, and low-cost methods. This review considers biosynthesis mechanism of bacteria, fungi, algae, plants, including role various biological substances processes reducing selenium compounds SeNPs their further packaging. Modern information approaches possible biomedical use presented: antimicrobial, antiviral, anticancer, antioxidant, anti-inflammatory, other properties, as well mechanisms these processes, that have important potential therapeutic value.

Язык: Английский

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Current trends, limitations and future research in the fungi?

Fungal Diversity, Год журнала: 2024, Номер 125(1), С. 1 - 71

Опубликована: Март 20, 2024

Abstract The field of mycology has grown from an underappreciated subset botany, to a valuable, modern scientific discipline. As this study grown, there have been significant contributions science, technology, and industry, highlighting the value fungi in era. This paper looks at current research, along with existing limitations, suggests future areas where scientists can focus their efforts, mycology. We show how become important emerging diseases medical discuss trends potential drug novel compound discovery. explore phylogenomics, its potential, outcomes address question phylogenomics be applied fungal ecology. In addition, functional genomics studies are discussed importance unravelling intricate mechanisms underlying behaviour, interactions, adaptations, paving way for comprehensive understanding biology. look research building materials, they used as carbon sinks, biocircular economies. numbers always great interest often written about estimates varied greatly. Thus, we needs order obtain more reliable estimates. aspects machine learning (AI) it mycological research. Plant pathogens affecting food production systems on global scale, such, needed area, particularly disease detection. latest data High Throughput Sequencing if still gaining new knowledge same rate before. A review nanotechnology is provided addressed. Arbuscular Mycorrhizal Fungi addressed acknowledged. Fungal databases becoming important, therefore provide major databases. Edible medicinal huge medicines, especially Asia prospects discussed. Lifestyle changes (e.g., endophytes, pathogens, and/or saprobes) also extremely trend special issue Diversity.

Язык: Английский

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A Critical Review on Nano-selenium Based Materials: Synthesis, Biomedicine Applications and Biocompatibility Assessment

Journal of Inorganic and Organometallic Polymers and Materials, Год журнала: 2024, Номер 34(7), С. 3037 - 3055

Опубликована: Янв. 11, 2024

Язык: Английский

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Biogenic selenium nanoparticles and selenium/chitosan-Nanoconjugate biosynthesized by Streptomyces parvulus MAR4 with antimicrobial and anticancer potential

BMC Microbiology, Год журнала: 2024, Номер 24(1)

Опубликована: Янв. 12, 2024

Abstract Background As antibiotics and chemotherapeutics are no longer as efficient they once were, multidrug resistant (MDR) pathogens cancer presently considered two of the most dangerous threats to human life. In this study, Selenium nanoparticles (SeNPs) biosynthesized by Streptomyces parvulus MAR4, nano-chitosan (NCh), their nanoconjugate (Se/Ch-nanoconjugate) were suggested be efficacious antimicrobial anticancer agents. Results SeNPs MAR4 NCh successfully achieved conjugated. The spherical with a mean diameter 94.2 nm high stability. Yet, Se/Ch-nanoconjugate was semispherical 74.9 much higher SeNPs, NCh, showed significant activity against various microbial strong inhibitory effect on tested metabolic key enzymes [phosphoglucose isomerase (PGI), pyruvate dehydrogenase (PDH), glucose-6-phosphate (G6PDH) nitrate reductase (NR)]; powerful agent. Furthermore, revealed cytotoxicity HepG2 (IC 50 = 13.04 μg/ml) moderate toxicity Caki-1 (HTB-46) tumor cell lines 21.35 but low WI-38 normal line 85.69 μg/ml). Nevertheless, displayed substantial IC values 11.82 7.83 μg/ml, respectively. Consequently, may more easily absorbed both lines. However, it exhibited very 153.3 μg/ml. Therefore, presented activity. Conclusion convincingly recommended used in biomedical applications versatile potent agents ensuring notable levels biosafety, environmental compatibility, efficacy.

Язык: Английский

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