Lecture notes on data engineering and communications technologies, Год журнала: 2025, Номер unknown, С. 699 - 709
Опубликована: Янв. 1, 2025
Язык: Английский
Lecture notes on data engineering and communications technologies, Год журнала: 2025, Номер unknown, С. 699 - 709
Опубликована: Янв. 1, 2025
Язык: Английский
World Journal of Microbiology and Biotechnology, Год журнала: 2023, Номер 39(8)
Опубликована: Май 15, 2023
Язык: Английский
Процитировано
9Marine Drugs, Год журнала: 2023, Номер 21(10), С. 538 - 538
Опубликована: Окт. 14, 2023
Three new polyketides (penidihydrocitrinins A–C, 1–3) and fourteen known compounds (4–17) were isolated from the deep-sea-derived Penicillium citrinum W17. Their structures elucidated by comprehensive analyses of 1D 2D NMR, HRESIMS, ECD calculations. Compounds 1–17 evaluated for their anti-inflammatory anti-osteoporotic bioactivities. All isolates exhibited significant inhibitory effects on LPS-stimulated nitric oxide production in murine brain microglial BV-2 cells a dose-response manner. Notably, compound 14 displayed strongest effect with IC50 value 4.7 µM. Additionally, 6, 7, 8 significantly enhanced osteoblast mineralization, which was comparable to that positive control, purmorphamine. Furthermore, these three also suppressed osteoclastogenesis dose-dependent manner under concentrations 2.5 μM, 5.0 10 μM.
Язык: Английский
Процитировано
9Deep Sea Research Part I Oceanographic Research Papers, Год журнала: 2024, Номер 205, С. 104237 - 104237
Опубликована: Янв. 19, 2024
Язык: Английский
Процитировано
3Journal of Asian Natural Products Research, Год журнала: 2025, Номер unknown, С. 1 - 27
Опубликована: Фев. 24, 2025
Marine fungi, rich in unique secondary metabolites with diverse activities, are a valuable source for novel lead compounds. Steroids, prominent class of bioactive compounds from marine have been extensively studied their pharmacological properties. This review describes the structural diversity, bioactivities, and sources 175 fungal steroids (2015-2023), mainly Aspergillus, Penicillium, Talaromyces, etc., seaweed, mangroves, sediments, animals like sponges corals. Among them, 74 exhibit antibacterial, antitumor, enzyme inhibitory, antiviral, other providing leads steroid drug development advancing pharmaceutical research.
Язык: Английский
Процитировано
0Lecture notes on data engineering and communications technologies, Год журнала: 2025, Номер unknown, С. 699 - 709
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0