Analytica Chimica Acta, Год журнала: 2025, Номер 1350, С. 343872 - 343872
Опубликована: Фев. 25, 2025
Язык: Английский
Exploration, Год журнала: 2023, Номер 3(1)
Опубликована: Фев. 1, 2023
The methodological advancements in surface-enhanced Raman scattering (SERS) technique with nanoscale materials based on noble metals, Au, Ag, and their bimetallic alloy Au-Ag, has enabled the highly efficient sensing of chemical biological molecules at very low concentration values. By employing innovative various type Ag nanoparticles especially, high efficiency Au@Ag nanomaterials as substrate SERS biosensors have revolutionized detection components including; proteins, antigens antibodies complex, circulating tumor cells, DNA, RNA (miRNA), etc. This review is about SERS-based Au/Ag enhanced activity by focusing different factors related to them. emphasis this research describe recent developments field conceptual behind Furthermore, article we apex understanding impact variation basic features like effects size, shape varying lengths, thickness core-shell influence large-scale magnitude morphology. Moreover, detailed information applications these importantly receptor binding domain (RBD) protein COVID-19 provided.
Язык: Английский
Процитировано
86
Journal of Nanobiotechnology, Год журнала: 2023, Номер 21(1)
Опубликована: Май 6, 2023
Abstract Surface-Enhanced Raman Scattering (SERS) technology, as a powerful tool to identify molecular species by collecting spectral signals at the single-molecule level, has achieved substantial progresses in fields of environmental science, medical diagnosis, food safety, and biological analysis. As deepening research is delved into SERS sensing, more high-performance or multifunctional substrate materials emerge, which are expected push sensing application fields. Especially field analysis, intrinsic extrinsic schemes have been widely used explored due their fast, sensitive reliable advantages. Herein, recent developments substrates applications biomolecular detection (SARS-CoV-2 virus, tumor etc.), imaging pesticide summarized. The concepts (including its basic theory mechanism) important strategies (extending from nanomaterials with tunable shapes nanostructures surface bio-functionalization modifying affinity groups specific biomolecules) for improving biosensing performance comprehensively discussed. For data analysis identification, machine learning methods software acquisition sources diagnosing discussed detail. In conclusion, challenges perspectives future presented.
Язык: Английский
Процитировано
79
Biosensors, Год журнала: 2021, Номер 11(12), С. 512 - 512
Опубликована: Дек. 13, 2021
The growing interest in the development of new platforms for application Raman spectroscopy techniques biosensor technologies is driven by potential these identifying chemical compounds, as well structural and functional features biomolecules. effect scattering a result inelastic light processes, which lead to emission scattered with different frequency associated molecular vibrations identified molecule. Spontaneous usually weak, resulting complexities separation weak inelastically intense Rayleigh scattering. These limitations have led various enhancing scattering, including resonance (RRS) nonlinear (coherent anti-Stokes stimulated spectroscopy). Furthermore, discovery phenomenon enhanced near metallic nanostructures gave impetus surface-enhanced (SERS) its combination spectroscopic techniques. resonant optical effects metal substrates or nanoparticles can be used increase speed, spatial resolution, signal amplification spectroscopy, making promising analysis characterization biological samples. This review provides main provisions listed advantages present when applied life sciences research. recent advances SERS SERS-combined are summarized, such SERRS, SE-CARS, SE-SRS bioimaging biosensing molecules, form basis future applications technology. In addition, an overview given tools success biosensors based on techniques, achieved choosing one following approaches: (i) fabrication reproducible substrate, (ii) synthesis nanotag, (iii) implementation on-site testing.
Язык: Английский
Процитировано
59
The Journal of Physical Chemistry A, Год журнала: 2022, Номер 126(47), С. 8781 - 8798
Опубликована: Ноя. 8, 2022
This Feature Article starts highlighting some recent experimental and theoretical advances in the field of IR Raman spectroscopy, giving a taste breadth dynamics this striving field. The local mode theory is then reviewed, showing how vibrational modes are derived from fundamental normal modes. New features introduced that add to current efforts: (i) unique measure bond strength based on force constants ranging bonding single molecules different environments periodic systems crystals (ii) new way interpret spectra by pinpointing probing interactions between particular stretching contributions All represents means work around very nature modes, namely motions polyatomic delocalized. Three focus points analysis reported, demonstrating extracts important information hidden spectroscopy data supporting experiments: metal–ligand heme proteins, such as myoglobin neuroglobin; disentanglement DNA modes; (iii) hydrogen water clusters ice. Finally, use other research groups summarized. Our vision future will be routinely applied community serves an incubator for collaborations experiment theory.
Язык: Английский
Процитировано
58
Biosensors and Bioelectronics, Год журнала: 2022, Номер 202, С. 114008 - 114008
Опубликована: Янв. 20, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected humans worldwide for over a year now. Although various tests have been developed the detection of SARS-CoV-2, advanced sensing methods are required diagnosis, screening, and surveillance disease 2019 (COVID-19). Here, we report surface-enhanced Raman scattering (SERS)-based immunoassay involving an antibody pair, SERS-active hollow Au nanoparticles (NPs), magnetic beads SARS-CoV-2. The selected pair against SARS-CoV-2 antigen, along with beads, facilitates accurate direct virus. NPs exhibit strong, reproducible SERS signals, allowing sensitive quantitative This assay had limits 2.56 fg/mL antigen 3.4 plaque-forming units/mL lysates. Furthermore, it facilitated identification in human nasopharyngeal aspirates diagnosis COVID-19 within 30 min using portable device. Thus, this can be potentially used prevention COVID-19.
Язык: Английский
Процитировано
54
Sensors and Actuators B Chemical, Год журнала: 2022, Номер 365, С. 131974 - 131974
Опубликована: Апрель 28, 2022
Язык: Английский
Процитировано
50
Biosensors and Bioelectronics, Год журнала: 2022, Номер 208, С. 114200 - 114200
Опубликована: Март 22, 2022
Язык: Английский
Процитировано
43
ACS Applied Nano Materials, Год журнала: 2022, Номер 5(10), С. 14051 - 14091
Опубликована: Сен. 23, 2022
The emergence of plasmonic nanostars with their attractive properties and unique versatility has enabled a wide range advanced technologies critical to human health, safety, energy, environmental remediation vast potential for further exploration. In addition superior surface-to-volume ratios compared those other nanostructures, arguably possess the largest numbers hotspots intensely amplified electric fields when they are subjected suitable electromagnetic waves trigger localized surface plasmon resonance (LSPR). These outstanding characteristics make ideal many applications that benefit from enhancement effect LSPR and/or large area. Over past decade, an increasing number research endeavors been reported on synthesis application advance state-of-the-art various existing technologies. contributions pertinent real-time image-guided multifunctional anticancer theranostics, ultrasensitive on-site detection devastating virus SARS-CoV-2, multimodal multiplexed brain imaging, greatly enhanced catalysts energy processes, or more efficient stable solar cells. important but familiar technologies, have also employed push technological frontiers in multiple enable such as maskless write-on lithography, nanosized field electron emitters, coherent random lasers, neural activity modulation, optically controlled electrical currents. Despite great performance since introduction, nascency this class nanostructures rise types nanostars, dominance gold recent years, indicate there still opportunities study, exploration, development. This Review outlines comprehensive picture current state nanostar focus scientific applications. We hope will enlighten future collective develop effective incorporate them into mainstream so these stars can truly shine.
Язык: Английский
Процитировано
40
Biophysical Reviews, Год журнала: 2023, Номер 15(2), С. 199 - 221
Опубликована: Апрель 1, 2023
Abstract Raman spectroscopy offers the potential for fingerprinting biological molecules at ultra-low concentration and therefore has detection of viruses. Here we review various techniques employed investigation Different are discussed including conventional spectroscopy, surface-enhanced tweezer, tip-enhanced Spectroscopy, coherent anti-Stokes scattering. Surface-enhanced scattering can play an essential role in viral by multiplexing nanotechnology, microfluidics, machine learning ensuring spectral reproducibility efficient workflow sample processing detection. The application these to diagnose SARS-CoV-2 virus is also reviewed. Graphical abstract
Язык: Английский
Процитировано
29
Nanoscale Advances, Год журнала: 2023, Номер 5(8), С. 2132 - 2166
Опубликована: Янв. 1, 2023
NIR-SERS and the concomitant tailoring of detection setup, as well tuning shape, material, architecture enhancing substrates, allow for bioanalytical studies, including cell through-tissue measurements.
Язык: Английский
Процитировано
24