Herein,
we
report
a
combination
of
experimental
and
computational
studies
for
the
synthesis
N-benzyl-N-methyl-1-phenylmethanamine
via
three
component
coupling
benzylamine,
benzaldehyde
CO2
under
light
irradiation
as
model
to
understand
reaction
mechanism
optimum
conditions
that
can
afford
this
efficiently.
We
performed
systematic
investigation
using
Density
Functional
Theory
(DFT)
revealed
formation
imine
two
intermediates
(I
&
II)
through
with
benzyl
amine
in
presence
excess
amount
phenyl
saline.
The
Molecular
electrostatic
potential
activation
energy
calculations
depicted
Intermediate
I
(formoxysilane)
by
insertion
into
Si-H
bond
silane
hydrogen
bonding.
Furthermore,
converted
II
reacting
saline
(PhSiH3),
followed
final
methylated
product
C-N
between
carbon
nitrogen
group.
Basrah Researches Sciences,
Год журнала:
2024,
Номер
50(1), С. 13 - 13
Опубликована: Июнь 30, 2024
The
measurement
of
magnesium
ion
in
homemade
pharmaceutical
samples
has
been
designed
using
a
fully
automated
microfluidic
device.
This
study
involved
the
design
three
channel
microchips
(45
×
3
cm).
Arduino
UNO
microcontrollers
were
used
to
operate
suggested
system.
DIY
micro-peristaltic
pumping
was
operated
by
first
type
that
for
remove
specimens
and
chemical
agents
extracted
from
microchip
transfer
them
UV.
Visible
spect.
apparatus
7-microliter
flow
cell.
other
type,
called
UNO,
employed
as
logger’s
data
alter,
record
outcomes
since
highest
point
corresponding
concentrations
an
Office
Excel
2016
application.
A
correlation
coefficient
(R2)
0.9997
linearity
varied
0.5
10
ppm
.
Ten
measurements
Mg
8
had
relative
standard
deviation
(0.872%).
Herein,
we
report
a
combination
of
experimental
and
computational
studies
for
the
synthesis
N-benzyl-N-methyl-1-phenylmethanamine
via
three
component
coupling
benzylamine,
benzaldehyde
CO2
under
light
irradiation
as
model
to
understand
reaction
mechanism
optimum
conditions
that
can
afford
this
efficiently.
We
performed
systematic
investigation
using
Density
Functional
Theory
(DFT)
revealed
formation
imine
two
intermediates
(I
&
II)
through
with
benzyl
amine
in
presence
excess
amount
phenyl
saline.
The
Molecular
electrostatic
potential
activation
energy
calculations
depicted
Intermediate
I
(formoxysilane)
by
insertion
into
Si-H
bond
silane
hydrogen
bonding.
Furthermore,
converted
II
reacting
saline
(PhSiH3),
followed
final
methylated
product
C-N
between
carbon
nitrogen
group.
