Insights into the Active Sites and Mechanism of Photochemical Synthesis of N-Benzyl-N-Methyl-1-Phenylmethanamine Via Coupling of Benzylamine, Benzaldehyde and Co2 Under Mild Conditions DOI
Suman L. Jain, Anil Malik, Nitish Saini

et al.

Published: Jan. 1, 2023

Herein, we report a combination of experimental and computational studies for the synthesis N-benzyl-N-methyl-1-phenylmethanamine via three component coupling benzylamine, benzaldehyde CO2 under light irradiation as model to understand reaction mechanism optimum conditions that can afford this efficiently. We performed systematic investigation using Density Functional Theory (DFT) revealed formation imine two intermediates (I & II) through with benzyl amine in presence excess amount phenyl saline. The Molecular electrostatic potential activation energy calculations depicted Intermediate I (formoxysilane) by insertion into Si-H bond silane hydrogen bonding. Furthermore, converted II reacting saline (PhSiH3), followed final methylated product C-N between carbon nitrogen group.

Language: Английский

Magnesium concentration in medicinal products using the fully controlled inkjet approach DOI

Ihsan Alasadi

Basrah Researches Sciences, Journal Year: 2024, Volume and Issue: 50(1), P. 13 - 13

Published: June 30, 2024

The measurement of magnesium ion in homemade pharmaceutical samples has been designed using a fully automated microfluidic device. This study involved the design three channel microchips (45 × 3 cm). Arduino UNO microcontrollers were used to operate suggested system. DIY micro-peristaltic pumping was operated by first type that for remove specimens and chemical agents extracted from microchip transfer them UV. Visible spect. apparatus 7-microliter flow cell. other type, called UNO, employed as logger’s data alter, record outcomes since highest point corresponding concentrations an Office Excel 2016 application. A correlation coefficient (R2) 0.9997 linearity varied 0.5 10 ppm . Ten measurements Mg 8 had relative standard deviation (0.872%).

Language: Английский

Citations

0
Light Induced, Metal Free, and Green Synthetic Approach for N-Methylation Via Coupling of Benzylamine, Benzaldehyde and Co2 at Atmospheric Pressure DOI
Suman L. Jain, Anil Malik, Nitish Saini

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0
Light-induced, metal free, and green synthetic approach for N-methylation via coupling of benzylamine, benzaldehyde and CO2 at atmospheric pressure DOI
Anil Malik, Nitish Saini, Ranjita S. Das

et al.

Molecular Catalysis, Journal Year: 2024, Volume and Issue: 569, P. 114562 - 114562

Published: Sept. 21, 2024

Language: Английский

Citations

0
Insights into the Active Sites and Mechanism of Photochemical Synthesis of N-Benzyl-N-Methyl-1-Phenylmethanamine Via Coupling of Benzylamine, Benzaldehyde and Co2 Under Mild Conditions DOI
Suman L. Jain, Anil Malik, Nitish Saini

et al.

Published: Jan. 1, 2023

Herein, we report a combination of experimental and computational studies for the synthesis N-benzyl-N-methyl-1-phenylmethanamine via three component coupling benzylamine, benzaldehyde CO2 under light irradiation as model to understand reaction mechanism optimum conditions that can afford this efficiently. We performed systematic investigation using Density Functional Theory (DFT) revealed formation imine two intermediates (I & II) through with benzyl amine in presence excess amount phenyl saline. The Molecular electrostatic potential activation energy calculations depicted Intermediate I (formoxysilane) by insertion into Si-H bond silane hydrogen bonding. Furthermore, converted II reacting saline (PhSiH3), followed final methylated product C-N between carbon nitrogen group.

Language: Английский

Citations

0